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Wei Yin, Ph.D.

Associate Professor
Undergraduate Program Director

Research Focus

Wei YinCardiovascular disease is the leading cause of death in the United Sates, and coronary artery disease is the most common type of cardiovascular disease. Shear stress induced by blood flow plays an important role in the initiation and development of atherosclerosis, the major reason for coronary artery disease. Circulating platelets and vascular endothelial cells are very sensitive to their mechanical environment; any change can affect their functions and interactions significantly. My major research interest is to investigate how altered blood flow and stress distribution affect platelet and endothelial cell behavior and lead to cardiovascular disease initiation. Computational fluid dynamics modeling, along with in vitro and ex vivo experiments, are carried out to study platelet and endothelial cell responses under physiologically relevant dynamic conditions. Biomarkers associated with platelet and endothelial cell activation are of special interest to us. We also work on numerical models to describe platelet coagulation kinetics and platelet adhesion to injured blood vessel wall under dynamic flow conditions.

Area of Interest

  • Cardiovascular dynamics and computational fluid dynamics
  • Platelet and endothelial cell functions under physiological and pathological flow conditions
  • Cardiovascular disease related inflammatory responses, especially complement activation
  • Effects of secondhand smoke on the development of cardiovascular diseases
  • Biomarker identification in cardiovascular diseases
  • Biomedical applications of aerogels

Education

  • M.S. Biomedical Engineering, 2001, The University of Akron, Akron, OH
  • Ph.D. Biomedical Engineering, 2004, Stony Brook University, Stony Brook, NY

Professional Experience

  • 2005 - 2007: Post-doctoral research fellow, Department of Pathology, Weill Medical College of Cornell University, New York, NY
  • 2007 - 2013: Assistant Professor, School of Mechanical and Aerospace Engineering, Oklahoma State University, Stillwater, Oklahoma
  • 2013 - 2016: Assistant Professor, Department of Biomedical Engineering, Stony Brook University, Stony Brook, NY
  • 2016 - current: Associate Professor, Department of Biomedical Engineering, Stony Brook University, Stony Brook, NY

Courses Taught

  • BME 430 - Quantitative Human Physiology (SBU)
  • BME 440 – Biomedical Engineering Design (SBU)
  • BME 441 - Senior Design Project in Biomedical Engineering (SBU)
  • BME 501 - Engineering Principles in Cell BIology (SBU)
  • ENGR 1111 – Introduction to Engineering (OSU)
  • MAE 3013 – Engineering Analysis (OSU)
  • MAE 3113 – Measurements and Instrumentation (OSU)
  • MAE 3723 – Dynamic Systems (OSU)
  • MAE 4623 – Biomechanics (OSU)
  • MAE 5013 – Basic Physiology for Engineers (OSU)
  • MAE 5053 – Advanced Engineering Statistics and Design of Experiments (OSU)
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