Maricedes Acosta-Martinez

Research Description: Neuroendocrinology, Neuroinflammation, and Placenta Physiology

Michael Airola

Research Description: The Airola lab studies the molecular details of lipid metabolism and transport and seeks to develop new pharmacological tools that inhibit lipid-modifying enzymes for the treatment of cancer and fungal disease

Ivet Bahar

Research Description: Our lab is interested in computer-aided design and development of small molecule modulators of protein function including orthosteric and allosteric drugs, and in modeling biomolecular interactions and their systemic effects at multiple scales.

Samuel Becker

Research Description: HOLD

Elizabeth Boon

Research Description: Chemical Biology, Enzymology, Bioinorganic Chemistry, and Spectroscopy

Mark Bowen

Research Description: Neurobiology. Protein supertertiary structure. Fluorescence microscopy .

Eric Brouzes

Research Description: Analyzing heterogeneity of cancer tissues

Christopher Brownlee

Research Description: Molecular mechanisms of spindle orientation, ciliogenesis, polarity, cytokinesis and axonogenesis

Nicholas Carpino

Research Description: Regulation of host responses to pathogen infection

Isaac Carrico

Research Description: Chemical Biology, Bioorganic Chemistry and Protein Engineering

Fei Chen

Research Description: Environmental risk factors in carcinogenesis with emphasis on metabolic and epigenetic reprograms during malignant transformation of the cells.

Leonard Cheung

Research Description: Pituitary function in physiology, aging, and disease

Jun Chung

Research Description: Mechanism of cancer invasion and metastasis

Chris Clarke

Research Description: Sphingolipid metabolism and signaling in tumorigenesis.

Holly Colognato

Research Description: Extracellular matrix in the brain: roles during development and during neurodegeneration

Zhaoqing Cong

Research Description: Bio-hybrid microrobotics and nanoscale drug delivery platforms for urological malignancies

Mehdi Damaghi

Research Description: Tumor evolution and adaptation in their microenvironment using spatial single cell technologies

Bruce Demple

Research Description: Cellular Systems to Counteract Oxidative Damage

Congwu Du

Research Description: In vivo optical imaging of neuronal-glio-vascular interactions and the effects of drug-elicited brain functional changes

Joshua Dubnau

Research Description: The effects of healthy aging on brain function, and on the mechanisms of age related neurodegenerative disorders. We specialize in the impacts of retrotransposons and endogenous retroviruses as drivers of aging and neurodegeneration, with a particular emphasis on signaling between glia and neurons. Our model organism of choice is the fruit fly, Drosophila, mainly because flies rule.

Grigori Enikolopov

Research Description: Stem cells; neurogenesis; imaging; signal transduction

Michael Frohman

Research Description: Lipid Signaling: Roles in mitochondrial biology, spermatogenesis, diabetes, immune function, the CNS, platelet activation, and cancer; - Imaging Pancreatic β-cells using metabolomics and MRI

Shaoyu Ge

Research Description: To examine the functional integration of new neurons into brain circuits

Steven Glynn

Research Description: X-ray crystallography, mechanistic biochemistry and protein design techniques to uncover the operating principles of energy-dependent proteolytic machines in mitochondria

Yusuf Hannun

Research Description: Lipid mediators of cancer cell signaling

Galadriel Hovel-Miner

Research Description: Discovery of novel genes and pathways associated with drug resistance in trypanosomatid parasites

Helen Hsieh

Research Description: Necrotizing Enterocolitis (NEC) and Neurodevelopment: the Role of Inflammation in Brain Development

Chi-Kuo Hu

Research Description: We study the biology of dormancy and its interaction with development and aging, using an intriguing research organism of the African killifish.

Leemor Joshua-Tor

Research Description: Structural Biology of gene expression, DNA replication, and small RNA biology

Martin Kaczocha

Research Description: Neuroscience, acute and chronic pain, drug development, lipid signaling

Hyungjin Kim

Research Description: DNA damage repair and cancer therapeutics; mechanisms of cancer drug actions and therapy response

Research Description: Biotechnology, Biology

Pawan Kumar

Research Description: IL-17 and IL-22 mediated intestinal mucosal host defense

Scott Laughlin

Research Description: Chemical Biology & Neuroscience

Feng-Qian Li

Research Description: Signaling: Cell Signaling, Cancer, Stem cells, Protein trafficking and Disease

Ke Jian (Jim) Liu

Research Description: Molecular mechanisms of metal carcinogenesis; DNA repair and somatic mutations

Yue Liu

Research Description: Organelle architecture; centrosomes and cilia biology; heart and brain development; infection and inflammation

Ed Luk

Research Description: How cells organize chromatin structure to accommodate and control gene expression

Michael Mak

Research Description: Mechanobiology and biophysics in cancer and development; biofabrication of ultra-realistic tissues and organoids for disease modeling and regeneration; computational modeling and biophysical informatics

Sandeep Mallipattu

Research Description: Our research program focuses on investigating the molecular mechanisms involved in the development and progression of kidney disease.

Peng Mao

Research Description: DNA repair and cancer mutations

Benjamin Martin

Research Description: Molecular basis of stem cell development and cancer pathogenesis

Luis Martinez

Research Description: p53 alterations in cancer

David McKinnon

Research Description: Molecular Physiology of Neuronal Firing Properties

Lisa Miller

Research Description: The chemical makeup of tissue in disease using high-resolution infrared and x-ray imaging

W. (Todd) Miller

Research Description: Signal transduction by tyrosine kinases

Jyoti Misra

Research Description: Growth regulation by the Hippo Signaling pathway in development and cancer

Ute Moll

Research Description: Tumor Suppressor Gene Research: Mechanism of p53 Inactivation

David Montrose

Research Description: Colon cancer, inflammatory bowel disease, microbiota, metabolism

Neil Nadkarni

Research Description: The NVITe lab seeks to understand relationships between various components of innate immunity and cerebrovascular dynamics in both preclinical and clinical stroke.

Dada Pisconti

Research Description: HOLD

Joshua Plotkin

Research Description: Striatal microcircuitry underlying normal behavior and disorders such as OCD

Edwin Pratt

Research Description: The Pratt Lab applies theranostic agents in combination to identify and treat various cancers including endometrial, ovarian and pancreatic, while determining points of resistance new theranostic agents

Michelino Puopolo

Research Description: Ion channels and neuronal excitability; mechanisms of pain

Gilbert Rahme

Research Description: Cancer epigenetics with a focus on brain tumors

Nancy Reich

Research Description: Signal Transduction and Activation of Gene Expression by Cytokines & Cellular Defense Responses to Viral Infection

Robert Rizzo

Research Description: Computational Research Projects in Cancer, HIV\AIDS, Influenza, and Method Development

Camila Dos Santos

Research Description: Epigenetic dependencies of normal and malignant breast development, with a focus on understanding paths to prevent cancer development and to attenuate the aggressiveness of already established cancer

Jessica Seeliger

Research Description: Membrane biosynthesis, structure & behavior in bacterial pathogenesis

Markus Seeliger

Research Description: Molecular Mechanism of Protein Kinase and Ubiquitin Ligase signaling in Cancer and Aging

Eugene Serbryany

Research Description: Protein misfolding and aggregation; protein and peptide libraries and sequencing; non-native protein conformations as novel drug targets or antigens

Roger Sher

Research Description: My research is committed to studying the complexity inherent in biological systems for the purpose of improving human health, focusing on Amyotrophic Lateral Sclerosis, Alzheimer's Disease, and neurodegenerative diseases

Mario Shields

Research Description: The mechanisms of development and progression of diseases affecting the exocrine pancreas, such as pancreatitis and pancreatic cancer

Kenneth Shroyer

Research Description: The molecular characterization of benign, premalignant, and malignant lesions of the female genital tract

Carlos Simmerling

Research Description: Computational Structural Biology

Ken-Ichi Takemaru

Research Description: Cell Signaling and Ciliogenesis in Mammalian Development, Health and Disease

Flaminia Talos

Research Description: Specification and clonal fate analysis of prostate epithelial cells in organogenesis and cancer

Dongyan Tan

Research Description: Structure and function of macromolecules in epigenetic regulation

Shao-Jun Tang

Research Description: Neuron-glia interaction in pain pathogenesis induced by opioids, HIV, or antiretroviral drugs

Gerald Thomsen

Research Description: Vertebrate Embryonic Development

Peter Tonge

Research Description: Chemical biology, pharmacology, mechanism of drug action, anticancer and antibacterial drug discovery, positron emission tomography (PET) imaging

Styliani-Anna (Stella) Tsirka

Research Description: Neuro-immune interactions: Cross-talk between the nervous and immune systems in health and disease

David Tuveson

Research Description: Pancreatic cancer, experimental therapeutics, diagnostics, mouse models, cancer genetics

Adrianus Van Der Velden

Research Description: The mammalian T cell response to Salmonella enterica serovar Typhimurium

Charles Vorkas

Research Description: Innate lymphocyte biology of infectious diseases and cancer; Mycobacterium tuberculosis, tick-borne diseases, and hematologic malignancies

Ledong Wan

Research Description: RNA Metabolism, Pancreatic Cancer, Inflammation

Zhishan Wang

Research Description: Environmental carcinogenesis, Cancer biology and Cancer therapy

Ryan Williams

Research Description: The Williams Translational Nanomedicine Lab synthesizes and tests nanoparticles to treat kidney diseases and for onboard diagnostics

Lonnie Wollmuth

Research Description: Molecular Mechanisms of Synaptic Function in the Brain

Chengfeng Yang

Research Description: RNA dysfunction in carcinogenesis and resistance to cancer therapies

Haojun Yang

Research Description: Investigating how nutrient signaling interfaces with mRNA translational control to uncover fundamental mechanisms of metabolic regulation and identify novel therapeutic targets for metabolic disease, cancer, and aging

Qiuhua Yang

Research Description: Metabolic and immune regulation of retinal degeneration

Vincent Yang

Research Description: Identifying the causes and treatment of gastrointestinal malignancies

Wei Yang

Research Description: Harnessing the power of multi-level proteomics to understand and prevent cancer metastasis

Huichun Zhan

Research Description: Pathogenesis and treatment of myeloproliferative neoplasms

Sufeng Zhang

Research Description: Engineering biomaterials and nanotherapeutics for gut inflammation targeting, mucosal healing, and immune modulation in inflammatory diseases

Michael Airola

Research Description: The Airola lab studies the molecular details of lipid metabolism and transport and seeks to develop new pharmacological tools that inhibit lipid-modifying enzymes for the treatment of cancer and fungal disease

Eric Brouzes

Research Description: Analyzing heterogeneity of cancer tissues

Christopher Brownlee

Research Description: Molecular mechanisms of spindle orientation, ciliogenesis, polarity, cytokinesis and axonogenesis

Fei Chen

Research Description: Environmental risk factors in carcinogenesis with emphasis on metabolic and epigenetic reprograms during malignant transformation of the cells.

Jun Chung

Research Description: Mechanism of cancer invasion and metastasis

Chris Clarke

Research Description: Sphingolipid metabolism and signaling in tumorigenesis.

Mehdi Damaghi

Research Description: Tumor evolution and adaptation in their microenvironment using spatial single cell technologies

Bruce Demple

Research Description: Cellular Systems to Counteract Oxidative Damage

Michael Frohman

Research Description: Lipid Signaling: Roles in mitochondrial biology, spermatogenesis, diabetes, immune function, the CNS, platelet activation, and cancer; - Imaging Pancreatic β-cells using metabolomics and MRI

Yusuf Hannun

Research Description: Lipid mediators of cancer cell signaling

Hyungjin Kim

Research Description: DNA damage repair and cancer therapeutics; mechanisms of cancer drug actions and therapy response

Feng-Qian Li

Research Description: Signaling: Cell Signaling, Cancer, Stem cells, Protein trafficking and Disease

Richard Lin

Research Description: Intracellular signaling molecules that regulate cell growth

Ke Jian (Jim) Liu

Research Description: Molecular mechanisms of metal carcinogenesis; DNA repair and somatic mutations

Ed Luk

Research Description: How cells organize chromatin structure to accommodate and control gene expression

Yupo Ma

Research Description: Leukemic Stem Cells; Stem Cell Therapy

Cungui Mao

Research Description: Bioactive sphingolipids in cell growth, differentiation, apoptosis, and autophagy

Peng Mao

Research Description: DNA repair and cancer mutations

Benjamin Martin

Research Description: Molecular basis of stem cell development and cancer pathogenesis

Luis Martinez

Research Description: p53 alterations in cancer

W. (Todd) Miller

Research Description: Signal transduction by tyrosine kinases

Jyoti Misra

Research Description: Growth regulation by the Hippo Signaling pathway in development and cancer

Ute Moll

Research Description: Tumor Suppressor Gene Research: Mechanism of p53 Inactivation

David Montrose

Research Description: Colon cancer, inflammatory bowel disease, microbiota, metabolism

Gilbert Rahme

Research Description: Cancer epigenetics with a focus on brain tumors

Robert Rizzo

Research Description: Computational Research Projects in Cancer, HIV\AIDS, Influenza, and Method Development

Camila Dos Santos

Research Description: Epigenetic dependencies of normal and malignant breast development, with a focus on understanding paths to prevent cancer development and to attenuate the aggressiveness of already established cancer

Markus Seeliger

Research Description: Molecular Mechanism of Protein Kinase and Ubiquitin Ligase signaling in Cancer and Aging

Mario Shields

Research Description: The mechanisms of development and progression of diseases affecting the exocrine pancreas, such as pancreatitis and pancreatic cancer

Kenneth Shroyer

Research Description: The molecular characterization of benign, premalignant, and malignant lesions of the female genital tract

Flaminia Talos

Research Description: Specification and clonal fate analysis of prostate epithelial cells in organogenesis and cancer

Dongyan Tan

Research Description: Structure and function of macromolecules in epigenetic regulation

Peter Tonge

Research Description: Chemical biology, pharmacology, mechanism of drug action, anticancer and antibacterial drug discovery, positron emission tomography (PET) imaging

David Tuveson

Research Description: Pancreatic cancer, experimental therapeutics, diagnostics, mouse models, cancer genetics

Charles Vorkas

Research Description: Innate lymphocyte biology of infectious diseases and cancer; Mycobacterium tuberculosis, tick-borne diseases, and hematologic malignancies

Ledong Wan

Research Description: RNA Metabolism, Pancreatic Cancer, Inflammation

Chengfeng Yang

Research Description: RNA dysfunction in carcinogenesis and resistance to cancer therapies

Vincent Yang

Research Description: Identifying the causes and treatment of gastrointestinal malignancies

Wei Yang

Research Description: Harnessing the power of multi-level proteomics to understand and prevent cancer metastasis

Elizabeth Boon

Research Description: Chemical Biology, Enzymology, Bioinorganic Chemistry, and Spectroscopy

Christopher Brownlee

Research Description: Molecular mechanisms of spindle orientation, ciliogenesis, polarity, cytokinesis and axonogenesis

Isaac Carrico

Research Description: Chemical Biology, Bioorganic Chemistry and Protein Engineering

Bruce Demple

Research Description: Cellular Systems to Counteract Oxidative Damage

Miguel Garcia-Diaz

Research Description: Mechanisms of mitochondrial gene expression/Mechanisms of DNA synthesis and repair

Galadriel Hovel-Miner

Research Description: Discovery of novel genes and pathways associated with drug resistance in trypanosomatid parasites

Scott Laughlin

Research Description: Chemical Biology & Neuroscience

Jessica Seeliger

Research Description: Membrane biosynthesis, structure & behavior in bacterial pathogenesis

Markus Seeliger

Research Description: Molecular Mechanism of Protein Kinase and Ubiquitin Ligase signaling in Cancer and Aging

Peter Tonge

Research Description: Chemical biology, pharmacology, mechanism of drug action, anticancer and antibacterial drug discovery, positron emission tomography (PET) imaging

Michael Mak

Research Description: Mechanobiology and biophysics in cancer and development; biofabrication of ultra-realistic tissues and organoids for disease modeling and regeneration; computational modeling and biophysical informatics

Robert Rizzo

Research Description: Computational Research Projects in Cancer, HIV\AIDS, Influenza, and Method Development

Camila Dos Santos

Research Description: Epigenetic dependencies of normal and malignant breast development, with a focus on understanding paths to prevent cancer development and to attenuate the aggressiveness of already established cancer

Eugene Serbryany

Research Description: Protein misfolding and aggregation; protein and peptide libraries and sequencing; non-native protein conformations as novel drug targets or antigens

Carlos Simmerling

Research Description: Computational Structural Biology

Bruce Demple

Research Description: Cellular Systems to Counteract Oxidative Damage

Miguel Garcia-Diaz

Research Description: Mechanisms of mitochondrial gene expression/Mechanisms of DNA synthesis and repair

Galadriel Hovel-Miner

Research Description: Discovery of novel genes and pathways associated with drug resistance in trypanosomatid parasites

Hyungjin Kim

Research Description: DNA damage repair and cancer therapeutics; mechanisms of cancer drug actions and therapy response

Ke Jian (Jim) Liu

Research Description: Molecular mechanisms of metal carcinogenesis; DNA repair and somatic mutations

Peng Mao

Research Description: DNA repair and cancer mutations

Carlos Simmerling

Research Description: Computational Structural Biology

Zhishan Wang

Research Description: Environmental carcinogenesis, Cancer biology and Cancer therapy

Maricedes Acosta-Martinez

Research Description: Neuroendocrinology, Neuroinflammation, and Placenta Physiology

Mark Bowen

Research Description: Neurobiology. Protein supertertiary structure. Fluorescence microscopy .

Christopher Brownlee

Research Description: Molecular mechanisms of spindle orientation, ciliogenesis, polarity, cytokinesis and axonogenesis

Holly Colognato

Research Description: Extracellular matrix in the brain: roles during development and during neurodegeneration

Joshua Dubnau

Research Description: The effects of healthy aging on brain function, and on the mechanisms of age related neurodegenerative disorders. We specialize in the impacts of retrotransposons and endogenous retroviruses as drivers of aging and neurodegeneration, with a particular emphasis on signaling between glia and neurons. Our model organism of choice is the fruit fly, Drosophila, mainly because flies rule.

Grigori Enikolopov

Research Description: Stem cells; neurogenesis; imaging; signal transduction

Shaoyu Ge

Research Description: To examine the functional integration of new neurons into brain circuits

Helen Hsieh

Research Description: Necrotizing Enterocolitis (NEC) and Neurodevelopment: the Role of Inflammation in Brain Development

Martin Kaczocha

Research Description: Neuroscience, acute and chronic pain, drug development, lipid signaling

Scott Laughlin

Research Description: Chemical Biology & Neuroscience

David McKinnon

Research Description: Molecular Physiology of Neuronal Firing Properties

Neil Nadkarni

Research Description: The NVITe lab seeks to understand relationships between various components of innate immunity and cerebrovascular dynamics in both preclinical and clinical stroke.

Joshua Plotkin

Research Description: Striatal microcircuitry underlying normal behavior and disorders such as OCD

Michelino Puopolo

Research Description: Ion channels and neuronal excitability; mechanisms of pain

Gilbert Rahme

Research Description: Cancer epigenetics with a focus on brain tumors

Roger Sher

Research Description: My research is committed to studying the complexity inherent in biological systems for the purpose of improving human health, focusing on Amyotrophic Lateral Sclerosis, Alzheimer's Disease, and neurodegenerative diseases

Shao-Jun Tang

Research Description: Neuron-glia interaction in pain pathogenesis induced by opioids, HIV, or antiretroviral drugs

Styliani-Anna (Stella) Tsirka

Research Description: Neuro-immune interactions: Cross-talk between the nervous and immune systems in health and disease

Lonnie Wollmuth

Research Description: Molecular Mechanisms of Synaptic Function in the Brain

Qiuhua Yang

Research Description: Metabolic and immune regulation of retinal degeneration

Elizabeth Boon

Research Description: Chemical Biology, Enzymology, Bioinorganic Chemistry, and Spectroscopy

Mark Bowen

Research Description: Neurobiology. Protein supertertiary structure. Fluorescence microscopy .

Christopher Brownlee

Research Description: Molecular mechanisms of spindle orientation, ciliogenesis, polarity, cytokinesis and axonogenesis

Nicholas Carpino

Research Description: Regulation of host responses to pathogen infection

Leonard Cheung

Research Description: Pituitary function in physiology, aging, and disease

Holly Colognato

Research Description: Extracellular matrix in the brain: roles during development and during neurodegeneration

Michael Frohman

Research Description: Lipid Signaling: Roles in mitochondrial biology, spermatogenesis, diabetes, immune function, the CNS, platelet activation, and cancer; - Imaging Pancreatic β-cells using metabolomics and MRI

Chi-Kuo Hu

Research Description: We study the biology of dormancy and its interaction with development and aging, using an intriguing research organism of the African killifish.

Michael Mak

Research Description: Mechanobiology and biophysics in cancer and development; biofabrication of ultra-realistic tissues and organoids for disease modeling and regeneration; computational modeling and biophysical informatics

Sandeep Mallipattu

Research Description: Our research program focuses on investigating the molecular mechanisms involved in the development and progression of kidney disease.

W. (Todd) Miller

Research Description: Signal transduction by tyrosine kinases

Joshua Plotkin

Research Description: Striatal microcircuitry underlying normal behavior and disorders such as OCD

Mario Shields

Research Description: The mechanisms of development and progression of diseases affecting the exocrine pancreas, such as pancreatitis and pancreatic cancer

Ken-Ichi Takemaru

Research Description: Cell Signaling and Ciliogenesis in Mammalian Development, Health and Disease

Qiuhua Yang

Research Description: Metabolic and immune regulation of retinal degeneration

Ivet Bahar

Research Description: Our lab is interested in computer-aided design and development of small molecule modulators of protein function including orthosteric and allosteric drugs, and in modeling biomolecular interactions and their systemic effects at multiple scales.

Elizabeth Boon

Research Description: Chemical Biology, Enzymology, Bioinorganic Chemistry, and Spectroscopy

Mark Bowen

Research Description: Neurobiology. Protein supertertiary structure. Fluorescence microscopy .

Steven Glynn

Research Description: X-ray crystallography, mechanistic biochemistry and protein design techniques to uncover the operating principles of energy-dependent proteolytic machines in mitochondria

Leemor Joshua-Tor

Research Description: Structural Biology of gene expression, DNA replication, and small RNA biology

Wali Karzai

Research Description: Biochemistry and Structural biology of RNA-Protein Interactions, Translational Control of Gene Expression, and Drug Discovery

Lisa Miller

Research Description: The chemical makeup of tissue in disease using high-resolution infrared and x-ray imaging

W. (Todd) Miller

Research Description: Signal transduction by tyrosine kinases

Robert Rizzo

Research Description: Computational Research Projects in Cancer, HIV\AIDS, Influenza, and Method Development

Markus Seeliger

Research Description: Molecular Mechanism of Protein Kinase and Ubiquitin Ligase signaling in Cancer and Aging

Eugene Serbryany

Research Description: Protein misfolding and aggregation; protein and peptide libraries and sequencing; non-native protein conformations as novel drug targets or antigens

Carlos Simmerling

Research Description: Computational Structural Biology

Dongyan Tan

Research Description: Structure and function of macromolecules in epigenetic regulation