Steele, T.E and
Glynn, S.E. Mitochondrial AAA proteases: a stairway to degradation. (2019).
Mitochondrion. 49, 121-127.
Puchades, C.*, Ding, B.*, Song, A., Wiseman, R.L., Lander, G.C.,
Glynn, S.E. Unique structural features of the mitochondrial AAA+ protease AFG3L2 reveal the molecular
basis for activity in health and disease. (2019).
Molecular Cell. 75, 1073-1085. *co-first authors
Elmes, M.W., Prentis, L.E., McGoldrick. L.L., Giuliano, C.J., Sweeney, J.M., Joseph,
O.M., Che, J., Carbonetti, G.S., Studholme, K., Deutsch, D.G., Rizzo, R.C.,
Glynn, S.E., Kaczocha, M. (2019). FABP1 controls hepatic transport and biotransformation of D9-THC.
Scientific Reports,
Ding, B., Martin, D.W., Rampello, A.J.,
Glynn, S.E. (2018). Dissecting Substrate Specificities of the Mitochondrial AFG3L2 Protease.
Biochemistry. 57, 4225-4235. 9, 7588.
Puchades, C., Rampello, A.J., Shin, M., Giuliano, C.J., Wiseman, R.L.,
Glynn, S.E., Lander, G.C. (2017). Structure of the mitochondrial inner membrane AAA+ protease
YME1 gives insight into substrate processing.
Science, 358, 6363.
Glynn, S.E. (2017). Multifunctional mitochondrial AAA proteases. Frontiers in Molecular Biosciences.
4:34.
Baytshtok V., Chen J.,
Glynn S.E., Nager A.R., Grant R.A., Baker T.A. and Sauer R.T. (2017). Covalently linked HslU
hexamers support a probabilistic mechanism that links ATP hydrolysis to protein unfolding
and translocation. Journal of Biological Chemistry. 292, 56965-5704.
Rampello, A.J. and
Glynn, S.E. (in press). Identification of a degradation signal within substrates of the mitochondrial
i-AAA protease. Journal of Molecular Biology.
Shi H., Rampello A.J.,
Glynn S.E. (2016). Engineered AAA+ proteases reveal principles of proteolysis at the mitochondrial
inner membrane. Nat. Commun., 7, 13301.
Glynn S.E., Chien P. (2016). Sending protein aggregates into a downward spiral. Nat. Struct.
Mol. Biol., 23, 769-70.
Sirrs S., van Karnebeek C.D., Peng X., Shyr C., Tarailo-Graovac M., Mandal R., Testa
D., Dubin D., Carbonetti G.,
Glynn S.E., Sayson B., Robinson W.P., Han B., Wishart D., Ross C.J., Wasserman W.W., Hurwitz
T.A., Sinclair G., Kaczocha M. (2015). Defects in fatty acid amide hydrolase 2 in
a male with neurologic and psychiatric symptoms. Orphanet J Rare Dis., 28, 10-38.
Stinson BM, Nager AR,
Glynn SE, Schmitz KR, Baker TA, Sauer RT. (2013). Nucleotide binding and conformational switching
in the hexameric ring of a AAA+ machine. Cell, 153, 628-39.
Glynn, S.E., Nager, A.R., Baker, T.A. and Sauer, R.T. (2012). Dynamic and static components power
unfolding in topologically closed rings of a AAA+ proteolytic machine. Nat. Struct.
Mol. Biol., 19, 616-622.
Glynn, S.E., Martin, A., Nager, A.R., Baker, T.A. and Sauer R.T. (2009). Structures of asymmetric
ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machine.
Cell, 139, 744-756.
Glynn S.E., Baker P.J., Sedelnikova S.E., Davies C.L., Eadsforth T.C., Levy C.W., Rodgers H.F.,
Blackburn G.M., Hawkes T.R., Viner R. and Rice D.W. (2005). Structure and mechanism
of imidazole-glycerol phosphate dehydratase., Structure,13, 1807-1817.
Glynn, S.E., Baker, P.J., Sedelnikova, S.E., Levy, C.W., Rodgers, H.F., Blank, J.,Hawkes, T.R.
and Rice, D.W. (2005). Purification, crystallization and preliminary crystallographic
analysis of Arabidopsis thaliana imidazoleglycerol-phosphate dehydratase. Acta Crystallogr.
Sect. F, 61, 776-778.
Hartley, A.,
Glynn, S.E., Barynin, V., Baker, P.J., Sedelnikova, S.E., Verhees, C.H., de Geus, D., van der
Oost, J., Timson, D.J., Reece, R.J., Rice, D.W. (2004). Substrate specificity and
mechanism from the structure of Pyrococcus furiosus galactokinase. J. Mol. Biol.,
337, 387-398.
De Geus, D., Hartley, A., Sedelnikova, S.E.,
Glynn, S.E., Baker, P.J., Verhees, C.H., van der Oost, J. and Rice, D.W. (2003). Cloning, purification,
crystallization and preliminary crystallographic analysis of galactokinase from Pyrococcus
furiosus. Acta Crystallogr. Sect D, 59, 1819-1821.
|