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YEAR 7+
Jennifer Park
My research project aims to lay the foundation for targeting TIM gain-of-function as a way to sensitize cancer cells to oncogene-induced DNA replication stress. Our goal is to provide mechanistic insight into how deprotection of stalled forks potentiates oncogene-induced senescence (OIS) and how pre-malignant cells under replication stress overcome OIS and establish oncogenic transformation
Advisor: Hyungjin Kim
YEAR 6
Jay Gupta
Inhibiting FABP5 to reduce Nociceptor Hyperexcitability and Spontaneous Pain induced by Spinal Cord Injury
Advisor: Michelino Puopolo
Kathryn Malone
Assessing the effect of importing alpha localization on breast cancer migration and metastasis
Advisor: Christopher Brownlee
Andrew Resnick
Studying the role and function of Neutral Sphingomyelinase 2 in Breast Cancer
Advisor: Christopher Clarke
Zijian Shao
Dystrophins in Oligodendrocytes: New Insight into Brain Phenotypes in Duchenne Muscular Dystrophy
Advisor: Holly Colognato
Isaiah Taylor
Elucidating the effects of microgravity on skeletal homeostasis
Advisor: David Komatsu
YEAR 5
Gabriel Brill
I am studying the lipid mediated affects of IAPP on pancreatic beta cell insulin secretion and pancreatic beta cell toxicity
Advisor: Dan Raleigh
Arafat Khan
The role of DNA replication proteins in coordinating DNA damage responses and cellular senescence mechanisms when challenged with cytotoxic chemotherapy agents.
Advisor: Hyungjin Kim
Rideeta Raquib
Investigating how diverse membranes impact diacylglycerol O-acyltransferase 2 (DGAT2) activity and structurally characterizing a critical substrate donor enzyme in a unique bacterial sphingolipid pathway
Advisor: Michael Airola
Nathaniel Sweet
I am studying how diapause programs suspend developmental processes with no adverse affect on life
Advisor: Chi-Kuo Hu
Tuba Thakir
Studying how tumor-derived PTHrP–induced hypercalcemia drives cardiac dysfunction and arrhythmias in cancer cachexia
Advisor: Tobias Janowitz
YEAR 4
Javier Anduaga
Small and large molecule drug discovery for protein tyrosine phosphatases in metabolic disease, cancer, and neurological and neurodevelopmental diorders
Advisor: Nicholas Tonks
Jack Bauer
Yarrowia lipolytica origin licensing: structural biology, biochemistry, binding/kinetics
Advisor: Lemor Joshua-Tor
William Noah Brett
I have two research projects : 1) Investigating the role of cell cycle transcription factors in multiciliogenesis, and 2) Determining the role of DNA damage checkpoint proteins in multiciliogenesis
Advisor: Ute Moll
Adriana DiBua
Characterization of novel astrocyte subtype in HIV-induced neuropathic pain
Advisor: Shao-Jun Tang
Mark Maurelli
Niacin as an analgesic against nucleoside reverse transcriptase inhibitor (NRTI)-induced pain
Advisor: Shao-Jun Tang
Cuilee Sha
Necrotizing enterocolitis is a gastrointestinal disease of prematurity that results in neurodevelopmental delay and impairments in surviving patients. My research project uses both in vivo and in vitro models to elucidate key molecular and cellular factors that link the gut and brain in this devastating condition
Advisor: Helen Hsieh
YEAR 3
Ana Candia Flores
AMPK role in regulating oligodendrocyte myelination and differentiation
Advisor: Holly Colognato
Julia Gattozzi
Dissecting cellular heterogeneity and mechanisms of treatment resistance in castration resistance prostate cancer
Advisor: Flaminia Talos
Chelsea Kirkland
Leveraging DNABERT for Cancer Genomics: A Deep Learning Approach to Uncovering Disrupted Gene Regulation in Colorectal Cancer
Advisor: Ramana Davuluri
Matthew Licht
Understanding the mechanisms of drug resistance, discovering drugs capable of overcoming resistance, and building tools to accomplish the former tasks
Advisor: Ivet Bahar
Ruby Pan
Investigating the role of CCDC186 in neurodevelopmental epilepsy
Advisor: Ken-ichi Takemaru
Laurel Schappell
Features and consequence of microglial phagocytosis of neutrophils in ischemic stroke
Advisor: Neil Nadkarni
YEAR 2
Salma Balogun
Studying alternative polyadenylation (APA) in podocyte injury and glomerular disease, focusing on kidney-specific genes and the therapeutic modulation of APA isoforms using antisense oligonucleotides.
Advisor: Shipra Agrawal
Brian Farrell
Abl Kinase Allosteric Resistance Mechanisms
Advisor: Markus Seeliger
Michael Fiore
Characterization of specific disease associated variants (DAVs) in the C- Terminal domain of the GluN2B subunit of N-methyl-D-aspartate (NMDA) receptors
Advisor: Lonnie Wollmuth
Sabrina Hafeez
Elucidating the role of NMDA receptors on the development of neural crest cells.
Advisor: Benjamin Martin
Rulan Jiang
Structural and Functional study of INO80 chromatin remodeler in DNA damage response
Advisor: Dongyan Tan
Natalie Lo
My project studies how genotoxic anti-cancer therapies trigger DNA replication fork instability to modulate cell fate from therapy-induced senescence towards cell death in the context of ovarian cancer
Advisor: Hyungjin Kim
Alexander Rhee
William Sander
Early epigenetic reprogramming primes the emergence of revival stem cells following intestinal injury
Advisor: Agnieska Bialkowska
Yushan Wang
Determining Chronic Arsenic Exposure Links to Brain Vascular Damage and Dementia
Advisor: Ke-Jian Liu
YEAR 1
Labiba Aziz
Allison Galante
Structure of peptide-NMDAR interaction in alzheimer's disease
Advisor: Hiro Furukawa
David Guber
Minxin Huang
Jaden Jimenez
Raisa Karim
characterizing the role of Klf5 in DSS-induced colitis (inflammation and recovery) using a VillinCreERT2 Klf5 fl/+ mouse model
Advisor: Agnieska Bialkowska
Yuxuan Lin
Investigating the role of TH in Pituitary Stem Cell Differentiation
Advisor: Leonard Cheung
Aaron Lyons
Shreya Madan
Abigail Murthy
Stilianos Papazahariou
Identifying epigenetic lesions in IDH-mutant gliomas
Advisor: Gilbert Rahme
Andrew Smith
Jasmine Stansil
Advisor: Shao-Jun Tang
Katelyn Thompson
Naomi Young
- MS students
