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Christian Ruiz

Christian Ruiz

PhD candidate in the Genetics Program

' Metabolic Signatures Associated with KRAS driven Lung Cancer'

Synopsis: Non-small-cell lung cancer (NSCLC) is the leading cause of cancer related deaths in the world. Oncogenic KRAS are one of the most common mutations in NSCLC cancer, with approximately 40% of lung tumors containing KRAS mutations. In addition, KRAS mutations predict a poor outcome and a poor response to conventional therapy as well as targeted therapy. As such, it is essential we continue to understand the consequences of these mutations. Cancer cells require extensive metabolic reprogramming in order to provide the biomass needed to sustain their proliferative state. Recent studies highlight a role for KRASmut in driving altered cancer metabolism as part of its mechanism of action. The goal of my thesis is to identify metabolic signatures associated with oncogenic events such as KRAS. The long-term goal of my studies is to help develop more effective treatment for KRASmut driven NSCLC.

Biography: Chrisitan was born in Pereira, Colombia and came to the US when he was a toddler and was raised in New York. He received a bachelor's degree in engineering from The City College of New York. Christian is currently a fifth-year PhD candidate in the Genetics Program here at Stony Brook University. He was a REU in Nanotechnology summer research intern and a Bridge to the Doctorate Fellow. 

MONday, APRIL 9, 2018 at 12:30 PM




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