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2015 Publications 

Chahales P and DG Thanassi. 2015. A more flexible lipoprotein sorting pathway. J. Bacteriol. 197:1702-4.

Chahales P and DG Thanassi. 2015. Structure, function, and assembly of adhesive organelles by uropathogenic bacteria. Microbiol. Spectr. 3(5). doi: 10.1128/microbiolspec.UTI-0018-2013.

Chung LK and JB Bliska. 2015. Yersinia versus host immunity: how a pathogen evades or triggers a protective response. Curr. Opin. Microbiol. 29:56-62.

Dalrymple NA, Cimica V and ER Mackow. 2015. Dengue virus NS proteins inhibit RIG-I/MAVS signaling by blocking TBK1/IRF3 phosphorylation: Dengue vrus serotype 1 NS4A is a unique interferon-regulating virulence determinant. MBio. 6(3):e00553-15.

Lee S, Wang W, Lee Y, and NS Sampson. 2015. Cyclic acetals as cleavable linkers for affinity capture. Org. Biomol. Chem. 13:8445-52.

Lu R, Schmitz W and NS Sampson. 2015. α-Methyl acyl CoA racemase provides Mycobacterium tuberculosis catabolic access to cholesterol esters. Biochemistry. 54:5669-72.

Mackow ER, Gorbunova EE and IN Gavrilovskaya. 2015. Endothelial cell dysfunction in viral hemorrhage and edema. Front. Microbiol. 5:733.

Obar JJ and BS Sheridan. 2015. Tracking cytotoxic potential in vivo. Cell. Mol. Immunol. 12:505-7.

Tan L, Li G, Parker KA, and NS Sampson. 2015. Ru-Catalyzed Isomerization Provides Access to Alternating Copolymers via Ring-Opening Metathesis Polymerization. Macromolecules. 48:4793-4800.

Toledo A, Pérez A, Coleman JL, and JL Benach. 2015. The lipid raft proteome of Borrelia burgdorferi. Proteomics. 15:3662-3675.

Toledo A, Monzón JD, Coleman JL, Garcia-Monco JC, and JL Benach. 2015. Hypercholesterolemia and ApoE deficiency result in severe infection with Lyme disease and relapsing-fever Borrelia. Proc. Natl. Acad. Sci. U. S. A. 112:5491-5496.

Touchette MH, Bommineni GR, Delle Bovi RJ, Gadbery JE, Nicora CD, Shukla AK, Kyle JE, Metz TO, Martin DW, Sampson NS, Miller WT, Tonge PJ, and JC Seeliger. 2015. Diacyltransferase activity and chain length specificity of Mycobacterium tuberculosis PapA5 in the synthesis of alkyl β-diol lipids. Biochemistry. 54:5457-68.

Touchette MH, Holsclaw CM, Previti ML, Solomon VC, Leary JA, Bertozzi CR, and JC Seeliger. 2015. The rv1184c locus encodes Chp2, an acyltransferase in Mycobacterium tuberculosis polyacyltrehalose lipid biosynthesis. J. Bacteriol. 197:201-10.

Van Vlack ER and JC Seeliger. 2015. Using riboswitches to regulate gene expression and define gene function in mycobacteria. Methods Enzymol. 550:251-65.

Wang H, Liu L, Lu Y, Pan P, Hooker JM, Fowler JS and PJ Tonge. 2015. Radiolabelling and positron emission tomography of PT70, a time-dependent inhibitor of InhA, the Mycobacterium tuberculosis enoyl-ACP reductase. Bioorg. Med. Chem. Lett. 25:4782-6.

Werneburg GT, Henderson NS, Portnoy EB, Sarowar S, Hultgren SJ, Li H, and DG Thanassi. 2015. The pilus usher controls protein interactions via domain masking and is functional as an oligomer. Nat. Struct. Mol. Biol. 22:540-6.

Yang M, Lu R, Guja KE, Wipperman MF, St Clair JR, Bonds AC, Garcia-Diaz M, and NS Sampson. 2015. Unraveling cholesterol catabolism in Mycobacterium tuberculosis: ChsE4-ChsE5 α2β2 acyl-CoA dehydrogenase initiates β-oxidation of 3-oxo-cholest-4-en-26-oyl CoA. A. C. S. Infect. Dis. 1:110-125

Yu W, Neckles C, Chang A, Bommineni GR, Spagnuolo L, Zhang Z, Liu N, Lai C, Truglio J, and PJ Tonge. 2015. A [(32)P]NAD(+)-based method to identify and quantitate long residence time enoyl-acyl carrier protein reductase inhibitors. Anal. Biochem. 474:40-9.

Zhang Y, Tam JW, Mena P, van der Velden AW, and JB Bliska. 2015. CCR2+ inflammatory dendritic cells and translocation of antigen by type III secretion are required for the exceptionally large CD8+ T cell response to the protective YopE69-77 epitope during Yersinia infection. PLoS Pathog. 11(10):e1005167.