| Immune Activation and Myocardial Recovery in Peripartum Cardiomyopathy |
2009-09-30T00:00:00 |
2013-12-31T00:00:00 |
University of Pittsburgh |
Nonfederal |
1400 |
Closed |
| A Multi-Center, Placebo-Controlled, Study to Evaluate the Safety of GSK716155 and
its Effects on Myocardial Metabolism, Myocardial Function, and Exercise Capacity in
Patients with NYHA Class II/III Congestive Heart Failure
|
2011-05-10T00:00:00 |
2013-06-15T00:00:00 |
GlaxoSmithKline |
Nonfederal |
52263.4 |
Closed |
| The Balance Study: Treatment of Hyponatremia Based on Lixivaptan in NYHA Class III/IV
Cardiac Patient Evaluation
|
2008-04-23T00:00:00 |
2011-12-02T00:00:00 |
Cardiokine Biopharma, LLC |
Nonfederal |
13530 |
Closed |
| A Randomized, Double-Blind, Placebo-Controlled, Multiple-Dose Study to Evaluate the
Effects of Alagebrium on Exercise in Subjects with Diastolic Heart Failure
|
2008-10-24T00:00:00 |
2010-10-08T00:00:00 |
Synvista Therapeutics Incorporated |
Nonfederal |
3300 |
Closed |
| A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the
Effect of Intravenous BG9928 on Body Weight in Subjects with Acute Decompensated Heart
Failure and Renal Insufficiency
|
2009-04-30T00:00:00 |
2011-02-11T00:00:00 |
Biogen Idec |
Nonfederal |
5000 |
Closed |
| SITE 1055: Double-Blinded, Placebo-Controlled, Multicenter Acute Study of Clinical
Effectiveness of Nesiritide in Subjects with Decompensated Heart Failure
|
2008-05-22T00:00:00 |
2012-01-13T00:00:00 |
Scios Incorporated |
Nonfederal |
140500 |
Closed |
| Pre-Determine: Biologic Markers and MRI SCD Cohort Study |
2012-07-01T00:00:00 |
2015-01-06T00:00:00 |
Brigham and Womens Hospital |
Nonfederal |
300 |
Closed |
| Management of Patients with Acutely Decompensated Heart Failure |
2012-05-14T00:00:00 |
2014-05-02T00:00:00 |
OptumHealth Care Solutions Incorporated |
Nonfederal |
37800 |
Closed |
| Cyclin Dependent Kinase G in Cardiac Development |
2006-09-01T00:00:00 |
2009-03-31T00:00:00 |
National Heart Lung and Blood Institute |
Federal |
761150.48 |
Closed |
| Solvay Pharma: A Double-Blind, Placebo-Controlled, Randomized, Multi-Center, Dose-Finding
Study of SLV320, a Selective A1 Adenosine Receptor Antagonist, to Evaluate the Effect
on Renal Function and Safety in Subjects Hospitalized.....
|
2009-09-10T00:00:00 |
2010-07-08T00:00:00 |
Quintiles Incorporated |
Nonfederal |
3000 |
Closed |
| A Phase II/III, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study to
Evaluate the Efficacy and Safety of Relaxin in Subjects with Acute Heart Failure
|
2010-08-30T00:00:00 |
2013-07-30T00:00:00 |
Corthera Incorporated |
Nonfederal |
5500 |
Closed |
| MIRACLE EF Study: Cardiac Resynchronization Therapy in Heart Failure |
2013-01-23T00:00:00 |
2015-04-28T00:00:00 |
Medtronic Incorporated |
Nonfederal |
12266 |
Closed |
| Cardiorentis: Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled
Trial to Evaluate the Efficacy and Safety of Ularitide (Urodilatin) Intravenous Infusion
in Patients Suffering from Acute Decompensated Heart Failure
|
2013-03-18T00:00:00 |
2015-05-20T00:00:00 |
Quintiles Incorporated |
Nonfederal |
5875 |
Closed |
| Phosphodiesterase Type 5 Inhibition with Tadalafil Changes Outcomes in Heart Failure
(PITCH-HF)
|
2013-12-02T00:00:00 |
2015-05-05T00:00:00 |
New England Research Institute |
Nonfederal |
2500 |
Closed |
| INTERVENE-HF Integrated Diagnostics Driven Diuretic & Chronic Medication Management
for Heart Failure
|
2016-08-02T00:00:00 |
2017-08-02T00:00:00 |
Medtronic Incorporated |
Nonfederal |
1428 |
Approved |
| Entresto (LCZ696) In Hospitalized Advanced Heart Failure (LIFE Study) |
2017-02-28T00:00:00 |
2018-10-31T00:00:00 |
Duke University |
Nonfederal |
1 |
Approved |
| Multicenter, Randomized, Double-Blind, Parallel Group, Active-Controlled Study to
Evaluate the Efficacy and Safety of Both Aliskiren Monotherapy and Aliskiren/Enalapril
Combination Therapy Compared to Enalapril Monotherapy, on Morbidity...
|
2009-11-10T00:00:00 |
2017-05-31T00:00:00 |
Novartis Pharmaceuticals Corporation |
Nonfederal |
56869.41 |
Closed |
| RiboCor: A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate D-Ribose
for the Treatment of Congestive Heart Failure
|
2013-09-24T00:00:00 |
2017-03-31T00:00:00 |
Integrium LLC |
Nonfederal |
6448.58 |
Closed |
| A Phase IIa, Single-Blind, Placebo-Controlled, Crossover, Multi-Center, Randomized
Study to Assess The Safety, Tolerability, and Preliminary Efficacy of a Single Intravenous
Dose of Ischemia-Tolerant Allogeneic Mesenchymal Bone Marrow....
|
2015-02-27T00:00:00 |
2017-12-05T00:00:00 |
CardioCell Limited Liability Company |
Nonfederal |
236993.25 |
Approved |
| ATHENA: Aldosterone Targeted Neurohormonal Combined with Natriuresis Therapy-HF |
2015-02-06T00:00:00 |
2017-04-30T00:00:00 |
Duke University |
Nonfederal |
27185 |
Closed |
| INcrease Of VAgal TonE in chronic Heart Failure (INOVATE-HF) |
2013-09-09T00:00:00 |
2017-05-01T00:00:00 |
BioControl Medical Incorporated |
Nonfederal |
31071.8 |
Approved |
| A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study to Evaluate
the Efficacy, Safety and Tolerability of Serelaxin When Added to Standard Therapy
in Acute Heart Failure Patients
|
2014-01-28T00:00:00 |
2018-11-26T00:00:00 |
Novartis Pharmaceuticals Corporation |
Nonfederal |
66726.61 |
Approved |
| International Registry to Assess mEdical Practice with IOngitudinal Observation for
Treatment of Heart Failure (Report-HF)
|
2015-10-20T00:00:00 |
2018-05-24T00:00:00 |
Novartis Pharmaceuticals Corporation |
Nonfederal |
55603.5 |
Approved |
| Observational Registry of Treatment Patterns in U.S. Heart Failure Patients with Reduced
Ejection Fraction
|
2016-10-25T00:00:00 |
2018-09-27T00:00:00 |
Novartis Pharmaceuticals Corporation |
Nonfederal |
22440 |
Approved |
| Phase II Trial to Study Efficacy Safety Pharmacokinetic & Pharmacodynamic Effects
of the Oral Partial Adenosine A1 Receptor Agonist Neladenoson Bialanate over 20 weeks
in Patients with Chronic Heart Failure with Reduced Ejection Fraction
|
2017-04-25T00:00:00 |
2018-04-11T00:00:00 |
Bayer Healthcare Pharmaceuticals Incorporated |
Nonfederal |
20065.2 |
Approved |
| A Randomized Parallel-Group, Placebo-Controlled, Double-Blind, Event-Driven, Multi-Center
Pivotal Phase III Clinical Outcome Trial of Efficacy and Safety of the Oral sGC Stimulator
Vericiguat in Subjects With Heart Failure With Reduced...
|
2017-05-16T00:00:00 |
2018-02-21T00:00:00 |
Merck Sharp and Dohme Corporation |
Nonfederal |
10937 |
Approved |
| Prevention of Non-Surgical Bleeding by Management of HeartMate II Patients without
Antiplatelet Therapy
|
2017-06-07T00:00:00 |
2018-03-08T00:00:00 |
St. Jude Medical Incorporated |
Nonfederal |
15180 |
Approved |
| Quintiles: A Phase III Randomized, Double-Blind Trial to Evaluate Efficacy and Safety
of Once Daily Empagliflozin 10 mg Compared to Placebo, in Patients with Chronic Heart
Failure with Preserved Ejection Fraction (HFpEF)
|
2017-11-02T00:00:00 |
2018-09-19T00:00:00 |
Boehringer Ingelheim Pharmaceutical |
Nonfederal |
7875 |
Approved |
| Quintiles: A Phase III Randomized, Double-Blind Trial to Evaluate Efficacy and Safety
of Once Daily Empagliflozin 10mg Compared to Placebo in Patients with Chronic Heart
Failure with Reduced Ejection Fraction (HFrEF)
|
2017-12-28T00:00:00 |
2018-10-20T00:00:00 |
Boehringer Ingelheim Pharmaceutical |
Nonfederal |
1 |
Approved |
