Synthesis of coral-shaped gold nanoparticles for SERS sensing applications
This research describes a new method of aqueous synthesis of gold nanoparticles in the presence of cetyltrimethylammonium bromide and folic acid through a seed-mediated growth approach. These nanoparticles have a shape similar to corals, and therefore, we referred to them as 'gold nanocorals' (AuNCs). Specifically, AuNCs consist of a solid core surrounded densely by branches. The branches exhibit nanosized roughness that creates multiple plasmonic hot-spots that increase AuNCs' SERS activity. In this study, we demonstrated that at the fast scanning times necessary for biomedical applications, AuNCs wxhibit an analytical enhancement factor greatot than 10 3 and 7 times greater enhancement of the Raman signal compared to gold nanostars. AuNCs-based SERS substrates demonstrated a good ability to reproduce signals collected, and thereby confirmed AuNCs feasibility in generating reliable and sensitive SERS substrates.
*Darienzo R, Karius K, Obla N, Chang C, Mironava T. Mater. Res. Express 2018; 5:095003