
Background
Francisella tularensis is an intracellular, gram-negative bacterium that invades macrophages and initiates the human immune response.
Technology
Tularemia, commonly known as ?rabbit fever? can be communicated across several species including; rabbits, rodents and humans. The murine monoclonal antibody recognizes a native epitope of Francisella tularensis ?Live Vaccine Strain?; IgG monoclonal antibody clone 164 against a native epitope of Francisella tularensis protein, LpnA/Tu14.
Advantages
The antibody was developed from a mouse infected with F.tularensis live vaccine strain and not recombinant protein, therefore representing a natural antibody made by the mouse in defence of infection against the native F. tularensis protein.
Application
Western blot - ELISA - Immunoprecipitation - Immunofluorescence assays
Inventors
Jorge Benach, Professor, Molecular Genetics & Microbiology
Anne Savitt, Research Assistant Professor, Molecular Genetics & Microbiology
Licensing Potential
Licensing
Licensing Status
Available for license.
Licensing Contact
Valery Matthys, Licensing Associate, Intellectual Property Partners, valery.matthys@stonybrook.edu,
Patent Status
Tech Id
8098