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Monoclonal Antibody, Anti Ft LVS LpnA/Tu14 Clone 164
An intracellular bacterium that can initiate the human response to Tularemia
Source: Gavin Allanwood, unsplash.com/photos/hcxqLJjI99E, Unsplash Licence

Background

Francisella tularensis is an intracellular, gram-negative bacterium that invades macrophages and initiates the human immune response.

Technology

Tularemia, commonly known as ?rabbit fever? can be communicated across several species including; rabbits, rodents and humans. The murine monoclonal antibody recognizes a native epitope of Francisella tularensis ?Live Vaccine Strain?; IgG monoclonal antibody clone 164 against a native epitope of Francisella tularensis protein, LpnA/Tu14.

Advantages

The antibody was developed from a mouse infected with F.tularensis live vaccine strain and not recombinant protein, therefore representing a natural antibody made by the mouse in defence of infection against the native F. tularensis protein.

Application

Western blot - ELISA - Immunoprecipitation - Immunofluorescence assays

Inventors

Jorge Benach, Professor, Molecular Genetics & Microbiology
Anne Savitt, Research Assistant Professor, Molecular Genetics & Microbiology

Licensing Potential

Licensing

Licensing Status

Available for license.

Licensing Contact

Valery Matthys, Licensing Associate, Intellectual Property Partners, valery.matthys@stonybrook.edu,

Patent Status

 

 

Tech Id

8098