Skip Navigation
Back to Search Innovations
Enzymatic Capsulotomy for Shoulder Adhesive Capsulitis
A minimally invasive collagenase injection method for treating frozen shoulder that is cost-effective
Source: Jesper Aggergaard,, Unsplash Licence


Adhesive capsulitis of the shoulder, more commonly known as frozen shoulder, results in painful limitation of shoulder motion. It can arise idiopathically or after trauma. The current standard of care is a long course of painful physical therapy to restore shoulder motion. Failing that, patients? often undergo surgical procedures, such as manipulation under general anesthesia, arthroscopy, or even open shoulder surgery.


Patients suffering from frozen shoulder may be able to avoid a long course of painful physical therapy, manipulation under general anesthesia, arthroscopy or open shoulder surgery. Instead, researchers from Stony Brook University have invented a less invasive and more cost-effective collagenase injection, or short series of collagenase injections, which may provide relief from this painful and debilitating condition in a timelier manner.


Less invasive - More cost-effective - Quicker relief


Treatment of frozen shoulder


Marie Badalamente, Professor, Orthopaedics
Edward Wang, Associate Professor, Orthopedics

Licensing Potential


Licensing Status

Exclusive License - All Fields.

Licensing Contact

Donna Tumminello, Assistant Director, Intellectual Property Partners,, 6316324163

Patent Status


Undergoing FDA approval. PCT Publication No. US 2015-0174216.

Tech Id