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Nanoparticle Sensor Having a Nanofibrous Membrane Scaffold
Novel nanoparticle sensor with applications in sweat detection for medical monitoring.
Header image is purely illustrative. Source: Kullez/Flickr,, CC BY 2.0.


Perspiration contains useful medical information on physical conditions for those living in environments with high temperatures, or for those who engage in physical activity for extended periods of time. Because of this, there has been an increase in demand for the development of wearable sweat sensors. Progress has been made thus far, but challenges are present, such as lack of multifunctionality, biocompatibility, and flexibility. Also, they're high-cost and have insufficient sensitivity.


This technology consists of assembling functional nanoparticles within nanofibrous membranes in order to construct composite materials having adjustable, multifunctional, and flexible properties. One implementation describes a nanocomposite scaffold derived from the assembly of gold nanoparticles in a nanofibrous membrane with multiple layers. This happens through controlled interactions. The preferred embodiment is a three layer nanofiber membrane including cellulose nanofibers, cross-linked polyethylene glycol diacrylate, and nonwoven polyethylene terephthalate.


Sensors can be made for specific substances (i.e. ions, solutes, reagents) - Flexible, multifunctional, tunable, and biocompatible - device flexibility and wearability - Low-cost manufacturing


-Biological fluid sensors -Biomarker secretion sensors -Permeation of water


Benjamin Hsiao, Distinguished Professor, Chemistry
Chuan-Jian Zhong, ,
Mark Poliks, ,

Licensing Potential

Development partner,Commercial partner,Licensing

Licensing Status

Available for licensing.

Licensing Contact

Donna Tumminello, Assistant Director, Intellectual Property Partners,, 6316324163

Patent Status

Patent application submitted

Tech Id