Faculty

• Alphabetical

  Faculty

  Michael Airola, Assistant Professor, Biochemistry,  Structural biology of lipid modifying enzymes

  Mark Bowen, Professor, Physiology and Biohysics,  Single molecule spectroscopy; Coordination of post-synaptic glutamate receptor signaling by the MAGUK family of scaffolds

   

  Saikat Chowdhury, Biochemistry,  Cytoskeletal dynamics and regulation

  Carlos de los Santos, Professor, Pharmacology, Determination of the solution structure DNA molecules damaged by endogenous and exogenous agents

  Ken Dill,  Professor, Laufer Center,  Computer modeling of protein molecules and theory and principles of the machine mechanisms and evolution of cells

  Dale Deutsch, Professor, The uptake of anandamide and 2-AG (the endocannabinoids) and the neurobiochemistry and cell biology of the enzymes involved in their metabolism

  Jarrod B. French, Assistant Professor, Structure, function and mechanism of proteins and protein complexes involved in human nucleotide metabolism.

  Miguel-Garcia Diaz, Professor, Pharmacology, How deficiencies in mitochondrial gene expression cause multiple human pathologies

  J. Peter Gergen , Professor, Regulation of gene expression during Drosophila development

  David Green, Professor, Applied Math and Statistics,  How can macromolecular interactions be engineered in a rational manner to have the desired effects in a complex environment, such as a living organism?

  Steven Glynn, Associate Professor, Structure and mechanism of protein-unfolding machines in mitochondria

  Yusuf A. Hannun,  Professor, Medicine, Bioactive lipids in cancer pathogenesis and therapeutics

  Bernadette Holdener, Associate Professor, Understanding how defects in glycosylation lead to birth defects

  Nancy M. Hollingsworth, Distinguished Teaching Professor, Chromosome behavior in yeast meiosis

  Wali Karzai,  Professor, Structure and function of RNA-binding proteins and biochemical studies of the SmpB.tmRNA quality control system.

  Martin Kaczocha,  Assistant Professor, Anesthesiology, Role of fatty acid binding proteins in pain, inflammation, and related pathophysiologies: Endocannabinoid pharmacology and development of novel therapeutics.

  Chang-Jun Liu, Brookhaven National Lab, Flavinoid/isoflavinoid & Plant cell wall pathways, Protein engineering

  Erwin London, Distinguished Professor,  Structure, organization, and function of membrane proteins and membrane lipids.

  Ed Luk,  Assistant Professor, Chromosome biology and genome regulation

  Benjamin Martin, Associate Professor, Stem cell maintenance and differentiation, Developmental mechanisms of cancer pathogenesis

  David Q. Matus, Assistant Professor, Cell cycle regulation of morphogenesis and cell invasive behavior

  Lisa Miller, Brookhaven National Lab, Study of the chemical makeup of cells and tissues using synchrotron-based infrared and x-ray imaging

  Aaron Neiman, Professor and Chair, The cell biology of sporulation in yeast

  Lina Obeid, Professor, Medicine, Bioactive lipids in Inflammation, aging and cancer

  Daniel Raleigh, Professor, Chemistry, Protein folding, protein structure and the mechanism of amyloid formation

  Robert Rizzo, Professor, Applied Math and Statistics, Structure-based drug design using computational methods; docking, molecular dynamics, virtual screening

  Adam Rosebrock, Assistant Professor, Pathology, Regulation of central carbon metabolism during cell growth and division. Development of big data approaches for mass spectrometry metabolomic data

  Nicole Sampson, Professor, Chemistry, Protein structure and protein function and synthesizing chemical tools to probe and control biological function

  Jorg Schwender, Brookhaven National Lab, Metabolic flux analysis, central carbon metabolism pathways

  Jessica Seeliger, Professor, Pharmacology, Infectious disease, tuberculosis, lipid biosynthesis, membrane biology, enzymology

  Markus  Seeliger, Professor, Pharmacology,  Mechanism of protein kinases and ubiquitin ligases in cancer and aging

  John Shanklin, Brookhaven National Laboratory, Lipid modifying enzymes, Protein engineering, Plant oils

  Carlos Simmerling, Professor, Chemistry, Computational structural biology: to accurately simulate known properties of molecules, assist in the refinement and interpretation of experimental data and predict the results of future experiments

  Sanford Simon, Professor, Extracellular degradation by neutrophil proteases.

  Steven O. Smith, Professor, Structure and function of membrane proteins

  Swaminathan Subramanyam, Brookhaven National Lab, Toxins, Rational drug design, Databases, Structural genomics 

  Dongyan Tan, Assistant Professor, Pharmacology,  Structure and function of macromolecules involved in epigenetic regulation of gene expression

  Gerald Thomsen, Professor, Mechanisms of cell fate determination and embryonic development

  Peter Tonge, Professor, Chemistry,  How proteins control and modulate the properties of small molecule ligands

  Jin Wang, Professor, Chemistry,   Biomolecular folding and recognition, especially protein folding and protein-protein/protein-DNA interactions

  Lonnie Wollmuth,  Professor, Neurobiology,   Fundamental mechanisms underlying the operation of ionotropic glutamate receptors, ligand-gated ion channels that mediate fast cell-to-cell signaling in the nervous system 

• X-ray Crystallography

  Biochemistry

  Michael Airola, Assistant Professor, Biochemistry Structural biology of lipid modifying enzymes

  Elizabeth Boon,  Professor, Chemistry,  Nitric oxide signaling bacteria and regulation of biofilm formation

  Mark Bowen, Professor, Physiology and Biohysics,  Single molecule spectroscopy; Coordination of post-synaptic glutamate receptor signaling by the MAGUK family of scaffolds

  Deborah Brown, Professor, Biochemistry, Cholestrol/sphingolipid-rich domains in membrane signaling

  Isaac Carrico, Professor, Chemistry, Chemical biology

  Saikat Chowdhury, Biochemistry,  Cytoskeletal dynamics and regulation

  Dale Deutsch, Professor, The uptake of anandamide and 2-AG (the endocannabinoids) and the neurobiochemistry and cell biology of the enzymes involved in their metabolism

  Jarrod B. French, Assistant Professor, Structure, function and mechanism of proteins and protein complexes involved in human nucleotide metabolism.

  Miguel-Garcia Diaz, Professor, Pharmacology, How deficiencies in mitochondrial gene expression cause multiple human pathologies

  J. Peter Gergen , Professor, Regulation of gene expression during Drosophila development

  Steven Glynn, Associate Professor, Structure and mechanism of protein-unfolding machines in mitochondria

  Yusuf A. Hannun,  Professor, Medicine, Bioactive lipids in cancer pathogenesis and therapeutics

  Bernadette Holdener, Associate Professor, Understanding how defects in glycosylation lead to birth defects

  Nancy M. Hollingsworth, Distinguished Teaching Professor, Chromosome behavior in yeast meiosis

  Wali Karzai,  Professor, Structure and function of RNA-binding proteins and biochemical studies of the SmpB.tmRNA quality control system.

  Martin Kaczocha,  Assistant Professor, Anesthesiology, Role of fatty acid binding proteins in pain, inflammation, and related pathophysiologies: Endocannabinoid pharmacology and development of novel therapeutics.

  Chang-Jun Liu, Brookhaven National Lab, Flavinoid/isoflavinoid & Plant cell wall pathways, Protein engineering

  Erwin London, Distinguished Professor,  Structure, organization, and function of membrane proteins and membrane lipids.

  Ed Luk,  Assistant Professor, Chromosome biology and genome regulation

  Benjamin Martin, Associate Professor, Stem cell maintenance and differentiation, Developmental mechanisms of cancer pathogenesis

  David Q. Matus, Assistant Professor, Cell cycle regulation of morphogenesis and cell invasive behavior

  Aaron Neiman, Professor and Chair, The cell biology of sporulation in yeast

  Lina Obeid, Professor, Medicine, Bioactive lipids in Inflammation, aging and cancer

  Daniel Raleigh, Professor, Chemistry, Protein folding, protein structure and the mechanism of amyloid formation

  Adam Rosebrock, Assistant Professor, Pathology, Regulation of central carbon metabolism during cell growth and division. Development of big data approaches for mass spectrometry metabolomic data

  Nicole Sampson, Professor, Chemistry, Protein structure and protein function and synthesizing chemical tools to probe and control biological function

  Jorg Schwender, Brookhaven National Lab, Metabolic flux analysis, central carbon metabolism pathways

  Jessica Seeliger, Professor, Pharmacology, Infectious disease, tuberculosis, lipid biosynthesis, membrane biology, enzymology

  Markus  Seeliger, Professor, Pharmacology,  Mechanism of protein kinases and ubiquitin ligases in cancer and aging

  John Shanklin, Brookhaven National Laboratory, Lipid modifying enzymes, Protein engineering, Plant oils

  Sanford Simon, Professor, Extracellular degradation by neutrophil proteases.

  Steven O. Smith, Professor, Structure and function of membrane proteins

  Dongyan Tan, Assistant Professor, Pharmacology,  Structure and function of macromolecules involved in epigenetic regulation of gene expression

  Gerald Thomsen, Professor, Mechanisms of cell fate determination and embryonic development

  Peter Tonge, Professor, Chemistry,  How proteins control and modulate the properties of small molecule ligands

  Lonnie Wollmuth,  Professor, Neurobiology,   Fundamental mechanisms underlying the operation of ionotropic glutamate receptors, ligand-gated ion channels that mediate fast cell-to-cell signaling in the nervous system 

• Computational Biology

  Computational Biology 

  Ken Dill,  Professor, Laufer Center,  Computer modeling of protein molecules and theory and principles of the machine mechanisms and evolution of cells

  David Green, Professor, Applied Math and Statistics,  How can macromolecular interactions be engineered in a rational manner to have the desired effects in a complex environment, such as a living organism?

  Robert Rizzo, Professor, Applied Math and Statistics, Structure-based drug design using computational methods; docking, molecular dynamics, virtual screening

  Markus  Seeliger, Professor, Pharmacology,  Mechanism of protein kinases and ubiquitin ligases in cancer and aging

  Carlos Simmerling, Professor, Chemistry, Computational structural biology: to accurately simulate known properties of molecules, assist in the refinement and interpretation of experimental data and predict the results of future experiments

  Jin Wang, Professor, Chemistry,   Biomolecular folding and recognition, especially protein folding and protein-protein/protein-DNA interactions

• NMR Spectroscopy

   Structural Biology

  Michael Airola, Assistant Professor, Biochemistry Structural biology of lipid modifying enzymes

  Elizabeth Boon,  Professor, Chemistry,  Nitric oxide signaling bacteria and regulation of biofilm formation

  Mark Bowen, Professor, Physiology and Biohysics,  Single molecule spectroscopy; Coordination of post-synaptic glutamate receptor signaling by the MAGUK family of scaffolds

  Saikat Chowdhury, Biochemistry,  Cytoskeletal dynamics and regulation

  Ken Dill,  Professor, Laufer Center,  Computer modeling of protein molecules and theory and principles of the machine mechanisms and evolution of cells

  Jarrod B. French, Assistant Professor, Structure, function and mechanism of proteins and protein complexes involved in human nucleotide metabolism.

  Miguel-Garcia Diaz, Professor, Pharmacology, How deficiencies in mitochondrial gene expression cause multiple human pathologies

  Steven Glynn, Associate Professor, Structure and mechanism of protein-unfolding machines in mitochondria

  Lisa Miller, Brookhaven National Lab, Study of the chemical makeup of cells and tissues using synchrotron-based infrared and x-ray imaging

  Daniel Raleigh, Professor, Chemistry, Protein folding, protein structure and the mechanism of amyloid formation

  Adam Rosebrock, Assistant Professor, Pathology, Regulation of central carbon metabolism during cell growth and division. Development of big data approaches for mass spectrometry metabolomic dat

  Markus  Seeliger, Professor, Pharmacology,  Mechanism of protein kinases and ubiquitin ligases in cancer and aging

  John Shanklin, Brookhaven National Laboratory, Lipid modifying enzymes, Protein engineering, Plant oils

  Steven O. Smith, Professor, Structure and function of membrane proteins

  Swaminathan Subramanyam, Brookhaven National Lab, Toxins, Rational drug design, Databases, Structural genomics 

  Dongyan Tan, Assistant Professor, Pharmacology,  Structure and function of macromolecules involved in epigenetic regulation of gene expression

  Peter Tonge, Professor, Chemistry,  How proteins control and modulate the properties of small molecule ligands

  Jin Wang, Professor, Chemistry,   Biomolecular folding and recognition, especially protein folding and protein-protein/protein-DNA interactions

• Electron Cryo-Microscopy

  Membrane Biology

  Michael Airola, Assistant Professor, Biochemistry Structural biology of lipid modifying enzymes

  Deborah Brown, Professor, Biochemistry, Cholestrol/sphingolipid-rich domains in membrane signaling

  Saikat Chowdhury, Biochemistry,  Cytoskeletal dynamics and regulation

  Dale Deutsch, Professor, The uptake of anandamide and 2-AG (the endocannabinoids) and the neurobiochemistry and cell biology of the enzymes involved in their metabolism

  Jarrod B. French, Assistant Professor, Structure, function and mechanism of proteins and protein complexes involved in human nucleotide metabolism.

  Steven Glynn, Associate Professor, Structure and mechanism of protein-unfolding machines in mitochondria

  Yusuf A. Hannun,  Professor, Medicine, Bioactive lipids in cancer pathogenesis and therapeutics

  Martin Kaczocha,  Assistant Professor, Anesthesiology, Role of fatty acid binding proteins in pain, inflammation, and related pathophysiologies: Endocannabinoid pharmacology and development of novel therapeutics.

  Erwin London, Distinguished Professor,  Structure, organization, and function of membrane proteins and membrane lipids.

  Lina Obeid, Professor, Medicine, Bioactive lipids in Inflammation, aging and cancer

  Daniel Raleigh, Professor, Chemistry, Protein folding, protein structure and the mechanism of amyloid formation

  Jessica Seeliger, Professor, Pharmacology, Infectious disease, tuberculosis, lipid biosynthesis, membrane biology, enzymology

  Markus  Seeliger, Professor, Pharmacology,  Mechanism of protein kinases and ubiquitin ligases in cancer and aging

  John Shanklin, Brookhaven National Laboratory, Lipid modifying enzymes, Protein engineering, Plant oils

  Steven O. Smith, Professor, Structure and function of membrane and amyloid proteins

  Swaminathan Subramanyam, Brookhaven National Lab, Toxins, Rational drug design, Databases, Structural genomics 

  Lonnie Wollmuth,  Professor, Neurobiology,   Fundamental mechanisms underlying the operation of ionotropic glutamate receptors, ligand-gated ion channels that mediate fast cell-to-cell signaling in the nervous system 

• Neurobiology

  Neurobiology

  Steven O. Smith, Professor, Structure and function of membrane and amyloid proteins

  Lonnie Wollmuth,  Professor, Neurobiology,   Fundamental mechanisms underlying the operation of ionotropic glutamate receptors, ligand-gated ion channels that mediate fast cell-to-cell signaling in the nervous system 

• Drug Design and Development

  Drug Design and Development

  
  

  Michael Airola, Assistant Professor, Biochemistry Structural biology of lipid modifying enzymes

  Elizabeth Boon,  Professor, Chemistry,  Nitric oxide signaling bacteria and regulation of biofilm formation

  Dale Deutsch, Professor, The uptake of anandamide and 2-AG (the endocannabinoids) and the neurobiochemistry and cell biology of the enzymes involved in their metabolism

  Jarrod B. French, Assistant Professor, Structure, function and mechanism of proteins and protein complexes involved in human nucleotide metabolism.

  Yusuf A. Hannun,  Professor, Medicine, Bioactive lipids in cancer pathogenesis and therapeutics

  Martin Kaczocha,  Assistant Professor, Anesthesiology, Role of fatty acid binding proteins in pain, inflammation, and related pathophysiologies: Endocannabinoid pharmacology and development of novel therapeutics.

  Daniel Raleigh, Professor, Chemistry, Protein folding, protein structure and the mechanism of amyloid formation

  Robert Rizzo, Professor, Applied Math and Statistics, Structure-based drug design using computational methods; docking, molecular dynamics, virtual screening

  Carlos Simmerling, Professor, Chemistry, Computational structural biology: to accurately simulate known properties of molecules, assist in the refinement and interpretation of experimental data and predict the results of future experiments

  Peter Tonge, Professor, Chemistry,  How proteins control and modulate the properties of small molecule ligands

   

• Chemical Biology

  Chemical Biology

  
  

  Elizabeth Boon,  Professor, Chemistry,  Nitric oxide signaling bacteria and regulation of biofilm formation

  Isaac Carrico, Professor, Chemistry, Chemical biology

  Peter Tonge, Professor, Chemistry,  How proteins control and modulate the properties of small molecule ligands

  
  

   

• To be defined
   

   

• To be defined