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Faculty

  • Alphabetical

    Faculty

    Michael AirolaAssistant Professor, Structural biology of lipid modifying enzymes

    Elizabeth Boon,  Professor, Chemistry,  Nitric oxide signaling bacteria and regulation of biofilm formation

    Mark Bowen, Professor, Physiology and Biophysics,  Single molecule spectroscopy; Coordination of post-synaptic glutamate receptor signaling by the MAGUK family of scaffolds

    Ivet Bahar, Professor, molecular systems biology, modeling and simulations of structural dynamics and interactions, design of modulators of function, applications to complex diseases

    Isaac Carrico, Professor, Chemistry, Chemical biology

    Saikat Chowdhury,  Assistant Professor, Cytoskeletal dynamics and regulation, cryo-electron microscopy and cell biology

    Ken Dill,  Professor, Laufer Center,  Computer modeling of protein molecules and theory and principles of the machine mechanisms and evolution of cells

    Miguel-Garcia Diaz, Associate Professor, Pharmacology, Mechanisms of mitochondrial gene expression

    J. Peter Gergen , Professor, Regulation of gene expression during Drosophila development

    David Green, Professor,  Applied Math and Statistics,  How can macromolecular interactions be engineered in a rational manner to have the desired effects in a complex environment, such as a living organism?

    Steven Glynn, Associate Professor, Structure and mechanism of protein-unfolding machines in mitochondria

    Kathryn Gunn, Assistant Professor, Biochemistry and Cell Biology, Studying the regulation of pancreatic enzymes through quaternary structure using cryoEM and cryoET

    Yusuf A. Hannun,  Professor, Medicine, Bioactive lipids in cancer pathogenesis and therapeutics

    Bernadette Holdener, Associate Professor, Understanding how defects in glycosylation lead to birth defects

    Nancy M. Hollingsworth, Distinguished Teaching Professor, Chromosome behavior in yeast meiosis

    Chi-Kuo Hu, Assistant Professor, biology of dormancy during development and aging, with the African killifish as the main research organism.

    Wali Karzai,  Professor, Structure and function of RNA-binding proteins and biochemical studies of the SmpB.tmRNA quality control system.

    Martin Kaczocha Assistant Professor, Anesthesiology, Role of fatty acid binding proteins in pain, inflammation, and related pathophysiologies: Endocannabinoid pharmacology and development of novel therapeutics.

    Chang-Jun Liu, Brookhaven National Lab, Flavinoid/isoflavinoid & Plant cell wall pathways, Protein engineering

    Qun Liu, Brookhaven National Lab,  Structural biology of membrane proteins and host-pathogen interactions, cellular structure biology.

    Erwin London, Distinguished Professor,  Structure, organization, and function of membrane proteins and membrane lipids.

    Ed Luk,  Assistant Professor, Chromosome biology and genome regulation

    Benjamin Martin, Associate Professor, Stem cell maintenance and differentiation, Developmental mechanisms of cancer pathogenesis

    David Q. Matus, Assistant ProfessorCell cycle regulation of morphogenesis and cell invasive behavior

    Lisa Miller, Brookhaven National Lab, Study of the chemical makeup of cells and tissues using synchrotron-based infrared and x-ray imaging

    Todd Miller, Professor and Chair, Physiology and Biohysics, Signal transduction by tyrosine kinases 

    Aaron Neiman, Professor and Chair Biochemistry, The cell biology of sporulation in yeast

    Dada Pisconti , Associate Professor, Muscle stem cells; muscle development, regeneration and aging; muscular dystrophy; extracellular matrix; biology of proteoglycans.

    Robert Rizzo, Professor, Applied Math and Statistics, Structure-based drug design using computational methods; docking, molecular dynamics, virtual screening

    Nicole Sampson, Professor, Chemistry, Chemical biology, enzymology and metabolomics

    Jorg Schwender, Brookhaven National Lab, Metabolic flux analysis, central carbon metabolism pathways

    Jessica Seeliger, Associate Professor, Pharmacology, Infectious disease, tuberculosis, lipid biosynthesis, membrane biology, enzymology

    Markus  Seeliger, Associate Professor, Pharmacology,  Mechanism of protein kinases and ubiquitin ligases in cancer and aging

    Eugene Serebryany, Assistant Professor, Physiology and Biophysics and the Laufer Center, Protein folding, misfolding, aggregation, and conformation-phenotype relationships; disulfide bonds and protein chemistry; single-molecule protein sequencing; protein and peptide libraries.

    John Shanklin, Brookhaven National Laboratory, Lipid modifying enzymes, Protein engineering, Plant oils

    Carlos Simmerling, Professor, Chemistry, Computational structural biology: to accurately simulate known properties of molecules, assist in the refinement and interpretation of experimental data and predict the results of future experiments

    Steven O. Smith, Professor, Structure and function of membrane proteins

    Stuti Sharma, Mechanisms of membrane transporters using cryo-electron microscopy and biochemical tools

    Dongyan Tan, Assistant Professor, Pharmacology,  Structure and function of macromolecules involved in epigenetic regulation of gene expression

    Gerald Thomsen, Professor, Mechanisms of cell fate determination and embryonic development

    Peter Tonge, Professor, Chemistry,  How proteins control and modulate the properties of small molecule ligands

    Jin Wang, Professor, Chemistry,   Biomolecular folding and recognition, especially protein folding and protein-protein/protein-DNA interactions

    Lonnie Wollmuth Professor, Neurobiology,   Fundamental mechanisms underlying the operation of ionotropic glutamate receptors, ligand-gated ion channels that mediate fast cell-to-cell signaling in the nervous system 

  • Biochemistry

    Biochemistry

    Michael AirolaAssistant Professor, Biochemistry Structural biology of lipid modifying enzymes

    Elizabeth Boon,  Professor, Chemistry,  Nitric oxide signaling bacteria and regulation of biofilm formation

    Mark Bowen, Professor, Physiology and Biohysics,  Single molecule spectroscopy; Coordination of post-synaptic glutamate receptor signaling by the MAGUK family of scaffolds

    Isaac Carrico, Professor, Chemistry, Chemical biology

    Saikat Chowdhury, Biochemistry,  Cytoskeletal dynamics and regulation

    Miguel-Garcia Diaz, Professor, Pharmacology,  Mechanisms of mitochondrial gene expression

    J. Peter Gergen , Professor, Regulation of gene expression during Drosophila development

    Steven Glynn, Associate Professor, Structure and mechanism of protein-unfolding machines in mitochondria

    Kathryn Gunn, Assistant Professor, Biochemistry and Cell Biology, Studying the regulation of pancreatic enzymes through quaternary structure using cryoEM and cryoET

    Yusuf A. Hannun,  Professor, Medicine, Bioactive lipids in cancer pathogenesis and therapeutics

    Bernadette Holdener, Associate Professor, Understanding how defects in glycosylation lead to birth defects

    Nancy M. Hollingsworth, Distinguished Teaching Professor, Chromosome behavior in yeast meiosis

    Chi-Kuo Hu, Assistant Professor, biology of dormancy during development and aging, with the African killifish as the main research organism.

    Wali Karzai,  Professor, Structure and function of RNA-binding proteins and biochemical studies of the SmpB.tmRNA quality control system.

    Martin Kaczocha Assistant Professor, Anesthesiology, Role of fatty acid binding proteins in pain, inflammation, and related pathophysiologies: Endocannabinoid pharmacology and development of novel therapeutics.

    Chang-Jun Liu, Brookhaven National Lab, Flavinoid/isoflavinoid & Plant cell wall pathways, Protein engineering

    Erwin London, Distinguished Professor,  Structure, organization, and function of membrane proteins and membrane lipids.

    Ed Luk,  Assistant Professor, Chromosome biology and genome regulation

    Benjamin Martin, Associate Professor, Stem cell maintenance and differentiation, Developmental mechanisms of cancer pathogenesis

    David Q. Matus, Assistant ProfessorCell cycle regulation of morphogenesis and cell invasive behavior

    Todd Miller, Professor and Chair, Physiology and Biohysics, Signal transduction by tyrosine kinases 

    Aaron Neiman, Professor and Chair, The cell biology of sporulation in yeast

    Dada Pisconti ,Associate Professor, Muscle stem cells; muscle development, regeneration and aging; muscular dystrophy; extracellular matrix; biology of proteoglycans.

    Nicole Sampson, Professor, Chemistry, Chemical biology, enzymology and metabolomics

    Jorg Schwender, Brookhaven National Lab, Metabolic flux analysis, central carbon metabolism pathways

    Jessica Seeliger, Associate Professor, Pharmacology, Infectious disease, tuberculosis, lipid biosynthesis, membrane biology, enzymology

    Markus  Seeliger, Associate Professor, Pharmacology,  Mechanism of protein kinases and ubiquitin ligases in cancer and aging

    Eugene Serebryany, Assistant Professor, Physiology and Biophysics and the Laufer Center, Protein folding, misfolding, aggregation, and conformation-phenotype relationships; disulfide bonds and protein chemistry; single-molecule protein sequencing; protein and peptide libraries.

    John Shanklin, Brookhaven National Laboratory, Lipid modifying enzymes, Protein engineering, Plant oils

    Sanford Simon, Professor, Extracellular degradation by neutrophil proteases.

    Steven O. Smith, Professor, Structure and function of membrane proteins

    Stuti Sharma, Mechanisms of membrane transporters using cryo-electron microscopy and biochemical tools

    Dongyan Tan, Assistant Professor, Pharmacology,  Structure and function of macromolecules involved in epigenetic regulation of gene expression

    Gerald Thomsen, Professor, Mechanisms of cell fate determination and embryonic development

    Peter Tonge, Professor, Chemistry,  How proteins control and modulate the properties of small molecule ligands

    Lonnie Wollmuth Professor, Neurobiology,   Fundamental mechanisms underlying the operation of ionotropic glutamate receptors, ligand-gated ion channels that mediate fast cell-to-cell signaling in the nervous system 

  • Computational Biology

    Computational Biology 

    Ivet Bahar,Professor, molecular systems biology, modeling and simulations of structural dynamics and interactions, design of modulators of function, applications to complex diseases

    Ken Dill,  Professor, Laufer Center,  Computer modeling of protein molecules and theory and principles of the machine mechanisms and evolution of cells

    David Green, Professor, Applied Math and Statistics,  How can macromolecular interactions be engineered in a rational manner to have the desired effects in a complex environment, such as a living organism?

    Robert Rizzo, Professor, Applied Math and Statistics, Structure-based drug design using computational methods; docking, molecular dynamics, virtual screening

    Markus  Seeliger, Associate Professor, Pharmacology,  Mechanism of protein kinases and ubiquitin ligases in cancer and aging

    Carlos Simmerling, Professor, Chemistry, Computational structural biology: to accurately simulate known properties of molecules, assist in the refinement and interpretation of experimental data and predict the results of future experiments

    Jin Wang, Professor, Chemistry,   Biomolecular folding and recognition, especially protein folding and protein-protein/protein-DNA interactions

  • Structural Biology

     Structural Biology

    Michael AirolaAssistant Professor, Biochemistry Structural biology of lipid modifying enzymes

    Elizabeth Boon,  Professor, Chemistry,  Nitric oxide signaling bacteria and regulation of biofilm formation

    Mark Bowen, Professor, Physiology and Biohysics,  Single molecule spectroscopy; Coordination of post-synaptic glutamate receptor signaling by the MAGUK family of scaffolds

    Saikat Chowdhury, Biochemistry,  Cytoskeletal dynamics and regulation

    Ken Dill,  Professor, Laufer Center,  Computer modeling of protein molecules and theory and principles of the machine mechanisms and evolution of cells

    Miguel-Garcia Diaz, Associate Professor, Pharmacology,  Mechanisms of mitochondrial gene expression

    Steven Glynn, Associate Professor, Structure and mechanism of protein-unfolding machines in mitochondria

    Kathryn Gunn, Assistant Professor, Biochemistry and Cell Biology, Studying the regulation of pancreatic enzymes through quaternary structure using cryoEM and cryoET

    Qun Liu, Brookhaven National Lab,  Structural biology of membrane proteins and host-pathogen interactions, cellular structural biology.

    Lisa Miller, Brookhaven National Lab, Study of the chemical makeup of cells and tissues using synchrotron-based infrared and x-ray imaging

    Markus  Seeliger, Associate Professor, Pharmacology,  Mechanism of protein kinases and ubiquitin ligases in cancer and aging

    Eugene Serebryany, Assistant Professor, Physiology and Biophysics and the Laufer Center, Protein folding, misfolding, aggregation, and conformation-phenotype relationships; disulfide bonds and protein chemistry; single-molecule protein sequencing; protein and peptide libraries.

    John Shanklin, Brookhaven National Laboratory, Lipid modifying enzymes, Protein engineering, Plant oils

    Steven O. Smith, Professor, Structure and function of membrane proteins

    Dongyan Tan, Assistant Professor, Pharmacology,  Structure and function of macromolecules involved in epigenetic regulation of gene expression

    Peter Tonge, Professor, Chemistry,  How proteins control and modulate the properties of small molecule ligands

    Jin Wang, Professor, Chemistry,   Biomolecular folding and recognition, especially protein folding and protein-protein/protein-DNA interactions

  • Membrane Biology

    Membrane Biology

    Michael AirolaAssistant Professor, Biochemistry Structural biology of lipid modifying enzymes

    Saikat Chowdhury, Biochemistry,  Cytoskeletal dynamics and regulation

    Steven Glynn, Associate Professor, Structure and mechanism of protein-unfolding machines in mitochondria

    Yusuf A. Hannun,  Professor, Medicine, Bioactive lipids in cancer pathogenesis and therapeutics

    Martin Kaczocha Assistant Professor, Anesthesiology, Role of fatty acid binding proteins in pain, inflammation, and related pathophysiologies: Endocannabinoid pharmacology and development of novel therapeutics.

    Qun Liu, Brookhaven National Lab,  Structural biology of membrane proteins in cell death and stress; technology development for X-ray crystallography and cryo-EM.

    Erwin London, Distinguished Professor,  Structure, organization, and function of membrane proteins and membrane lipids

    Aaron Neiman, Professor and Chair, The cell biology of sporulation in yeast

    Jessica Seeliger, Associate Professor, Pharmacology, Infectious disease, tuberculosis, lipid biosynthesis, membrane biology, enzymology

    Markus  Seeliger, Associate Professor, Pharmacology,  Mechanism of protein kinases and ubiquitin ligases in cancer and aging

    John Shanklin, Brookhaven National Laboratory, Lipid modifying enzymes, Protein engineering, Plant oils

    Steven O. Smith, Professor, Structure and function of membrane and amyloid proteins

    Lonnie Wollmuth Professor, Neurobiology,   Fundamental mechanisms underlying the operation of ionotropic glutamate receptors, ligand-gated ion channels that mediate fast cell-to-cell signaling in the nervous system 

  • Neurobiology

    Neurobiology

    Saikat Chowdhury, Biochemistry,  Cytoskeletal dynamics and regulation, cryo-electron microscopy and cell biology

    Steven O. Smith, Professor, Structure and function of membrane and amyloid proteins

    Martin Kaczocha Assistant Professor, Anesthesiology, Role of fatty acid binding proteins in pain, inflammation, and related pathophysiologies: Endocannabinoid pharmacology and development of novel therapeutics.

    Lonnie Wollmuth Professor, Neurobiology,   Fundamental mechanisms underlying the operation of ionotropic glutamate receptors, ligand-gated ion channels that mediate fast cell-to-cell signaling in the nervous system 

  • Drug Design and Development

    Drug Design and Development


    Michael AirolaAssistant Professor, Biochemistry Structural biology of lipid modifying enzymes

    Elizabeth Boon,  Professor, Chemistry,  Nitric oxide signaling bacteria and regulation of biofilm formation

    Yusuf A. Hannun,  Professor, Medicine, Bioactive lipids in cancer pathogenesis and therapeutics

    Martin Kaczocha Assistant Professor, Anesthesiology, Role of fatty acid binding proteins in pain, inflammation, and related pathophysiologies: Endocannabinoid pharmacology and development of novel therapeutics.

    Robert Rizzo, Professor, Applied Math and Statistics, Structure-based drug design using computational methods; docking, molecular dynamics, virtual screening

    Nicole Sampson, Professor, Chemistry, Chemical biology, enzymology and metabolomics

    Markus  Seeliger, Associate Professor, Pharmacology,  Mechanism of protein kinases and ubiquitin ligases in cancer and aging

    Jessica Seeliger, Associate Professor, Pharmacology, Infectious disease, tuberculosis, lipid biosynthesis, membrane biology, enzymology

    Eugene Serebryany, Assistant Professor and Biophysics and the Laufer Center, Protein folding, misfolding, aggregation, and conformation-phenotype relationships; disulfide bonds and protein chemistry; single-molecule protein sequencing; protein and peptide libraries.

    Carlos Simmerling, Professor, Chemistry, Computational structural biology: to accurately simulate known properties of molecules, assist in the refinement and interpretation of experimental data and predict the results of future experiments

    Peter Tonge, Professor, Chemistry,  How proteins control and modulate the properties of small molecule ligands

     

  • Chemical Biology

    Chemical Biology


    Elizabeth Boon,  Professor, Chemistry,  Nitric oxide signaling bacteria and regulation of biofilm formation

    Isaac Carrico, Professor, Chemistry, Chemical biology

    Dada Pisconti, Associate Professor, Muscle stem cells; muscle development, regeneration and aging; muscular dystrophy; extracellular matrix; biology of proteoglycans.

    Nicole Sampson, Professor, Chemistry, Chemical biology, enzymology and metabolomics

    Markus  Seeliger, Associate Professor, Pharmacology,  Mechanism of protein kinases and ubiquitin ligases in cancer and aging

    Jessica Seeliger, Associate Professor, Pharmacology, Infectious disease, tuberculosis, lipid biosynthesis, membrane biology, enzymology

    Eugene Serebryany, Assistant Professor, Physiology and Biophysics and the Laufer Center, Protein folding, misfolding, aggregation, and conformation-phenotype relationships; disulfide bonds and protein chemistry; single-molecule protein sequencing; protein and peptide libraries.

    Peter Tonge, Professor, Chemistry,  How proteins control and modulate the properties of small molecule ligands

     

  • Cancer Biology

     Cancer Biology

    Miguel-Garcia Diaz, Associate Professor, Pharmacology,  Mechanisms of mitochondrial gene expression

    Yusuf A. Hannun,  Professor, Medicine, Bioactive lipids in cancer pathogenesis and therapeutics

    Benjamin Martin, Associate Professor, Stem cell maintenance and differentiation, Developmental mechanisms of cancer pathogenesis 

    David Q. Matus, Assistant ProfessorCell cycle regulation of morphogenesis and cell invasive behavior

    Markus  Seeliger, Associate Professor, Pharmacology,  Mechanism of protein kinases and ubiquitin ligases in cancer and aging

     

  • Cell Biology

    Cell Biology 

    Saikat Chowdhury, Biochemistry,  Cytoskeletal dynamics and regulation, cryo-electron microscopy and cell biology

    Kathryn Gunn, Assistant Professor, Biochemistry and Cell Biology, Studying the regulation of pancreatic enzymes through quaternary structure using cryoEM and cryoET

    Bernadette Holdener, Associate Professor, Understanding how defects in glycosylation lead to birth defects

    Martin Kaczocha Assistant Professor, Anesthesiology, Role of fatty acid binding proteins in pain, inflammation, and related pathophysiologies: Endocannabinoid pharmacology and development of novel therapeutics

    David Q. Matus, Assistant ProfessorCell cycle regulation of morphogenesis and cell invasive behavior

    Erwin London, Distinguished Professor,  Structure, organization, and function of membrane proteins and membrane lipids

    Benjamin Martin, Associate Professor, Stem cell maintenance and differentiation, Developmental mechanisms of cancer pathogenesis

    Aaron Neiman, Professor and Chair, The cell biology of sporulation in yeast

    Dada Pisconti Associate Professor, Muscle stem cells; muscle development, regeneration and aging; muscular dystrophy; extracellular matrix; biology of proteoglycans.