Browsing: Medicine

By genetically manipulating and removing the most common mutant form of the p53 gene that promotes colorectal cancer in humans, an international team of scientists demonstrated that this therapy reduces tumor growth and tissue invasion. Led by Ute Moll, MD, Professor and cancer biologist in the Department of Pathology at Stony Brook University School of Medicine, the findings are published in Cancer Cell. Specific ‘hotspot’ mutations of p53 have recently been recognized as strong promoters of cancer in humans. About 60 percent of colorectal cancers harbor p53 mutations. The challenge for scientists has been discovering whether and which mutant forms of p53…

Stony Brook University, iCell Gene Therapeutics and the University of Louisville have received Food and Drug Administration (FDA) clearance for an Investigational New Drug (IND) for the treatment of relapsed and refractory T-cell leukemia and lymphoma. The approach is the first to use chimeric antigen receptor engineered T-cells directed against the target protein CD4 (CD4CAR). Together, Stony Brook University, the University of Louisville, and iCell Gene Therapeutics expect the first in-human Phase I clinical trial to begin accruing patients before the end of 2018. “We are excited to partner with the University of Louisville and iCell Gene Therapeutics to offer this…

Luigi Pesce Ibarra, a doctoral candidate in Health and Rehabilitation Sciences with a concentration in Rehabilitation and Movement Sciences, shares his experience as an intern. Before departing Long Island for my 2018 summer internship at Stony Brook University’s Office of Federal Relations located off of Capitol Hill, I could not fully imagine the unique experience that awaited me when I stepped off the train at Union Station in Washington, DC. As a STEM PhD student focusing on Health and Rehabilitation Sciences, I have always been interested in federal policy and funding related to scientific research. Working with Stony Brook’s Director of…

Infertility treatments, such as in-vitro fertilization (IVF), are stressful experiences for women that can take large emotional tolls, especially when the treatment fails. At a time when extra support is needed, infertile women often report that family and friends urge them to “just relax” so they can conceive, causing women to feel as if their mental state is to blame for treatment failures. But a new study reveals evidence that women’s emotional state does not have a strong connection with the success of infertility treatment. Co-authored by Marci Lobel, PhD, Professor of Psychology and Jennifer Nicoloro SantaBarbara, MSW, MA,  and colleagues at…

The School of Social Welfare’s MSW and BSW programs have received reaccreditation from the Council on Social Work Education. “The reaccreditation process occurs every eight years, requiring the writing of a document which carefully assesses our processes and learning outcomes with students, our mission and goals, curriculum, admissions and student services, faculty, administration and resources, and diversity,” said Dean Jacqueline Mondros, D.S.W. The process also includes site visits and review by the Commission on Accreditation. According to Dean Mondros, a revamped MSW curriculum, with second year-specializations, will be in place next fall. “We think that the specializations will help graduates…

Keratin 17 (K17), a protein that promotes cancer, may prove to be a key target gene in the battle against pancreatic cancer. New research involving K17 as a therapeutic target against this lethal disease is being conducted by Kenneth Shroyer, MD, PhD, the Marvin Kuschner Professor and Chair of Pathology at Stony Brook Medicine, and Luisa Escobar-Hoyos, PhD, Assistant Professor and Co-Director of the Pathology Translational Research Lab. The Pancreatic Cancer Action Network (PanCAN) awarded Drs. Shroyer and Escobar-Hoyas a $500,000 grant to carry out this research. This is the first time a PanCAN grant has been awarded to Stony Brook University. The…

Kristina Gonzalez witnessed first-hand the birth of a newborn boy this spring when the high school senior shadowed Brian Hunt, MD, an assistant professor in the Department of Obstetrics/Gynecology at Stony Brook Medicine. “When I was with him, his patient went into labor and I got to see the baby being born,” said Kristina, who graduated this month from Longwood High School on Long Island. “It was an intense experience. I’d never seen anything like that in real life before and it opened my eyes to the possibility that I could have a career path in labor and delivery.” Her…

Some students enter the medical field inspired by television shows such as “Grey’s Anatomy.” Others are called by a personal experience. Such was the case for Alessandra Riccio ’18, who lost her cousin, Kristin Molini, at the age of 25 after a seven-year battle with a gastrointestinal disease that resulted in a five-organ transplant. “I was 10 years old at the time and she was in and out of hospitals and constantly going to the doctor,” said Alessandra. “She was on a J-tube to drain her intestines and I specifically remember a moment when she wanted me in the room…

Stony Brook University has been awarded $175,000 to open a state-of-the art infectious disease laboratory, which will have an insectary dedicated solely for work on ticks.  The funding is part of a package approved by the New York State Senate aimed at fighting Lyme and other tick-borne diseases (TBDs) throughout the state.The new funding will help support a wide variety of local investments identified by the Senate’s Task Force on Lyme and Tick-Borne Diseases to increase education, research, prevention, and treatment options, and combat the ongoing increase in TBDs throughout New York. The laboratory will be open to Stony Brook scientists and…

On a Wednesday morning at the Long Island State Veterans Home (LISVH) in Stony Brook, resident Al Anderson was feeling agitated. His wife was in the hospital, and not being there for her stirred up waves of emotion in the Vietnam veteran. Like many others who have served our country, Anderson now lives with anxiety, depression and post-traumatic stress disorder (PTSD). That day’s outcome would be different, however, thanks to a groundbreaking new initiative at the home, a major teaching affiliate of Stony Brook Medicine. Anderson would be among the first at the LISVH to try out their recently-acquired virtual…

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