Browsing: Research

Esther Sans Takeuchi, PhD, the William and Jane Knapp Endowed Chair in Energy and the Environment, a Distinguished Professor of Chemistry in the College of Arts & Sciences and in Materials Science and Chemical Engineering in the College of Engineering and Applied Sciences at Stony Brook University, Chief Scientist of the Energy Sciences Directorate at Brookhaven National Laboratory and the holder of more than 150 patents has been named a finalist for the European Inventor Award. The European Patent Office (EPO) selected Professor Takeuchi as a finalist in the category of “Non-EPO countries.” The winners of the EPO’s 2018 innovation prize will be announced at a…

An international team of scientists including David Q. Matus, PhD, and Benjamin L. Martin, PhD, in the Department of Biochemistry and Cell Biology and Stony Brook University Cancer Center researchers,  have developed a new cell imaging technology combining lattice light sheet microscopy (LLSM) and adaptive optics (AO) to create high-resolution “movies” of cells in their 3D environment that also captures subcellular processes. Published in Science, the research reveals a technology that shows the phenotypic diversity within cells across different organisms and developmental stages and in conditions such as mitosis, immune processes and in metastases. The AO-LLSM technique offers scientists investigating cancer and other…

By using computed tomography colonography (CTC), also known as virtual colonoscopy, to image many types of polyps, and matching those images to detailed gene expression data of those polyps, researchers may be able to determine what types of polyps will turn into cancer and which may not. The work is a research collaboration between Stony Brook University, led by Jerome Liang, PhD, and the University of Wisconsin School of Medicine and Public Health, led by Perry J. Pickhardt, MD, and  is supported by a new $3 million grant from the National Institutes of Health (NIH). The project, titled “Radiogenomics of Colorectal…

A new technology employing endocannabinoids for pain relief, developed by Stony Brook University researchers affiliated with the Institute of Chemical Biology and Drug Discovery (ICB & DD), has been licensed to Artelo Biosciences, Inc. Endocannabinoids are natural marijuana-like substances in the body and have potential as the basis for new medicines. Artelo has an exclusive license with the Research Foundation for the State University of New York to the intellectual property portfolio of FABP inhibitors for the modulation of the endocannabinoid system for the treatment of pain, inflammation and cancer. Fatty Acid Binding Proteins have been identified as intracellular transporters for the endocannabinoid…

The Microscopy Society of America (MSA) has selected Yimei Zhu — a Stony Brook University adjunct professor and a senior physicist at the U.S. Department of Energy’s Brookhaven National Laboratory (BNL) — to receive the 2018 Distinguished Scientist Award for physical sciences. This award annually recognizes two senior scientists, one in the physical sciences and the other in biological sciences, for their long-standing record of achievement in the field of microscopy and microanalysis. “I am extremely humbled by this recognition, the highest honor of the society, and to be selected among the most distinguished scientists in the field worldwide,” said Zhu,…

As the nation celebrates another Earth Day and Stony Brook pays homage to the planet with  programming aimed at spreading the green gospel to campus and community, Stony Brook students are fanning out with individual and collective projects that make a difference. Graduate student Lisa Herbert studies trace metals such as iron, manganese, nickel, cobalt and arsenic that are released into the Arctic Ocean by melting glaciers. Another graduate student, Lisa Prowant is working closer to home by charting the whereabouts of a Long Island inhabitant whose numbers are declining, the Eastern box turtle. And undergraduate Shauna Wright ’18 is part…

Stony Brook Medicine’s researchers and clinicians are leaders in their fields. They also are leading the way for students and junior faculty, by example and through teaching and mentorship. We asked six accomplished women to share their career journeys with us. Latha Chandran, MD, MPH When Dr. Chandran first began to attend meetings in her chosen profession of academic medicine, she sometimes was the only woman in the room – and even more frequently the only woman of color. Now, as Stony Brook University School of Medicine’s Vice Dean for Academic and Faculty Affairs, she is a strong voice for…

By combining data on pathology images of 13 types of cancer and correlating that with clinical and genomic data, a Stony Brook University-led team of researchers are able to identify tumor-infiltrating lymphocytes (TILs), called TIL maps, which will enable cancer specialists to generate tumor-immune information from routinely gathered pathology slides. Published in Cell Reports, the paper details how TIL maps are related to the molecular characterization of tumors and patient survival. The method may provide a foundation on how to better diagnose and create a treatment plan for cancers that are responsive to immune-based anti-cancer therapy, such as melanoma, lung, bladder,…

An exciting collaboration between Stony Brook University and the BeLocal organization has spawned the BeLocal-bridge project, a student initiative aimed at designing and building a badly needed bridge in Madagascar. The project’s team leader is Johnny Donza, a senior majoring in Civil Engineering in the College of Engineering and Applied Sciences. Together with his fellow Civil Engineering team members Manuela Corcho, Luke Papazian and Yuxin Xia  – all working under the direction of Prof. Harold Walker – Johnny has devoted much of his time over the past year to an innovative bamboo bridge design, already proposed for use in actual construction this summer in Madagascar. “For…

Professor Robert Patro of the Department of Computer Science has received a 2018 National Science Foundation (NSF) CAREER award for his research proposal, A Comprehensive and Lightweight Framework for Transcriptome Analysis. In layman’s terms, this project focuses on the field of RNA (ribonucleic acid) research and how to analyze sequencing data pertaining to it. In addition to performing various other functions in the cell, RNA acts as a messenger molecule, carrying instructions from DNA and acting as a template for protein synthesis. “As a researcher at an institution focused on developing engineering-driven solutions in medical research, his proposed project supports not only the mission…

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