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Daniel Klein, Ph.D.


State University of New York at Buffalo (1983)
Distinguished Professor, Clinical Psychology

Klein

Contact:

daniel.klein@stonybrook.edu
Office: Psychology A-338
Phone: (631) 632-7859

Visit Lab Website

Visit Temperament Study Website

Dr. Klein plans to admit a new graduate student pending approval of funding.

Research Interests:

Dr. Klein is interested in developmental psychopathology and adult psychopathology, particularly mood disorders in children, adolescents, and adults. His research explores the intergenerational transmission of depression; the roles of temperament and emotional reactivity, and early adversity in the development and course of mood disorders; the long-term course and continuity of mood disorders; the classification of mood disorders; comorbidity between depression and other disorders; and the psychotherapeutic and psychopharmacological treatment of depressive disorders.

Current Research:  

Dr. Klein is currently directing a longitudinal study of the role of early temperament and emotional style in the development of later mood and anxiety disorders in a large community sample of children. The children were assessed at ages 3, 6, 9, and 12, and an assessment at age 15 is currently underway. The study uses multiple measurement strategies to assess potential risk, protective, mediating, and moderating factors in multiple domains, including child emotional reactivity and regulation, executive functioning, psychopathology, psychophysiological and behavioral measures of biases in processing emotional information, susceptibility genes, stress and pubertal hormones, parenting, environmental and family stress, and parental personality and psychopathology. In addition, resting state and task-related functional magnetic resonance imaging (fMRI) measures were collected on a subset of the larger sample. 

Dr. Klein is also continuing to work with data sets from several past studies, including several multi-site clinical trials of the treatment of chronically depressed adults; a family and follow-up study of chronically depressed adult outpatients; and a family and follow-up study of a large community sample of adolescents. 

Recent Publications: 

In press

Beauchaine, T. P., Klein, D. N., Knapton, E. & Zisner, A. R. (in press). Anhedonia in depression: Assessment, mechanisms, and therapeutics. In J. Quevedo, A. F. Carvalho, & C. A. Zarate (Eds.),  Neurobiology of Depression . Elsevier. 
 
B ufferd, S.J., Dougherty, L.R., Olino, T.M., Dyson, M.W., Carlson, G.A., & Klein, D.N. (in press). Temperament distinguishes persistent from remitted anxiety disorders across early childhood.  Journal of Clinical Child and Adolescent Psychology .
 
Dougherty, L.R., Klein, D.N., & Olino, T.M. (in press). Depression in children and adolescents.    In J. Hunsley & E. Mash (Eds.),  A Guide to Assessments that Work  (2 nd  ed.). New York: Oxford University Press.
 
Farmer, R.F., Seeley, J.R., Gau, J.M., Klein, D.N., Merikangas, K.R., Kosty, D.B., Duncan, S.C., & Lewinsohn, P.M. (in press). Clinical features in probands associated with an increased risk for alcohol use disorders in family members.  Psychology of Addictive Behaviors .
 
Finsaas, M.C., Bufferd, S.M., Dougherty, L.R., Carlson, G.A., & Klein, D.N. (in press).  Preschool psychiatric disorders: Homotypic and heterotypic continuity through middle childhood and early adolescence.   Psychological Medicine .
 
Finsaas, M.C., Kessel, E.M., Dougherty, L.R., Bufferd, S.J., Danzig, A.P., Davila, J., Carlson, G.A., & Klein, D.N. (in press). Early childhood psychopathology prospectively predicts social functioning in early adolescence.  Journal of Clinical Child and Adolescent Psychology .
 
Frost, A., Kessel, E., Black, S., Goldstein, B., Bernard, K., & Klein, D.N. (in press). Homotypic and heterotypic continuity of internalizing and externalizing symptoms from age 3 to age 12: The moderating role of diurnal cortisol.  Development and Psychopathology. 
 
Furukawa, T.A., Efthimiou, O., Weitz, E.S., Cipriani, A., Keller, M.B., Kocsis, J.H., Klein, D,N., Michalak, J., Salanti, G., Cuijpers, P., & Schramm, E. (in press). Cognitive-behavioral analysis system of psychotherapy (CBASP), drug, or their combination for persistent depressive disorder: Personalizing the treatment choice using individual participant data network meta-regression.  Psychotherapy and Psychosomatics .
 
Goldstein. B.L., Shankman, S.A., Kujawa, A., Torpey-Newman, D.C., Dyson, M.W., Olino, T.M., & Klein, D.N. (in press). Positive and negative emotionality at age 3 predict change in EEG asymmetries across early childhood.  Journal of Abnormal Child Psychology .
 
Hausman, E.M., Kotov, R., Perlman, G., Hajcak, G., Kessel, E.M., & Klein, D.N. (in press). Prospective predictors of first onsets of depressive disorders in adolescent females with anxiety disorders.  Journal of Affective Disorders.
 
Klein, D.N., Finsaas, M.C., Goldstein, B.L., Kessel, E.M., Kopala-Sibley, D., & Kotov, R. (in press). Personality and depression. In V. Zeigler-Hill & T.K. Shackelford (Eds.),  The SAGE Handbook of Personality and Individual Differences. Los Angeles: Sage. 
 
Klein, D.N., & Mumper, E. (in press). Behavioral inhibition as a precursor to psychopathology. In  Behavioral Inhibition: Integrating Theory, Research, and Clinical Perspectives , K. Perez-Edgar and & N.A. Fox (Eds.). New York: Springer.
 
Kopala-Sibley, D.C., Cyr, M., Finsaas, M.C., Orawe, J., Huang, A., Tottenham, N., & Klein, D.N. (in press). Early childhood parenting predicts late childhood brain functional connectivity during emotion perception and reward.  Child Development .
 
Kopala-Sibley, D.C., Olino, T., Durbin, E., Dyson, M.W., & Klein, D.N. (in press). The stability of temperament from early childhood to early adolescence: A multi-method, multi-informant examination.  European Journal of Personality .
 
Kujawa, A., Carroll, A., Mukherjeea, D., Mumper, E., Kessel, E., Olino, T., Hajcak, G., & Klein, D.N. (in press). A longitudinal examination of event-related potentials sensitive to monetary reward and loss feedback from late childhood to middle adolescence. International Journal of Psychophysiology.
 
Kujawa, A., Hajcak, G., & Klein, D.N. (in press). Reduced reward responsiveness moderates the effect of maternal depression on depressive symptoms in offspring: Evidence across levels of analysis.  Journal of Child Psychology and Psychiatry. 
 
Meyer, A., Nelson, B., Perlman, G., Klein, D.N., & Kotov, R. (in press). A neural biomarker, the error-related negativity, predicts the new onset of generalized anxiety disorder in a large sample of adolescent females.  Journal of Child Psychology and Psychiatry.
 
Nelson, B.D., Kessel, E.M., Klein, D.N., & Shankman, SA. (in press). Depression symptom dimensions and asymmetrical cortical activity while anticipating reward.  Psychophysiology.
 
Olino, T.M., Benini, L., Icenogle, G., Wilson, S., Klein, D.N., Seeley, J.R., & Lewinsohn, P.M. (in press). Is the assessment of personality comparable in persons who have and have not experienced depressive, anxiety, and substance use disorders? An examination of measurement invariance.  Assessment.
 
Olino, T.M., Bufferd, S.J., Dougherty, L.R., Dyson, M.W., Carlson, G.A., & Klein, D.N.  (in press). The development of latent dimensions of psychopathology across early childhood: Stability of dimensions and moderators of change.  Journal of Abnormal Child Psychology.
 
Olino, T.M., Finsaas, M., Dougherty, L., & Klein, D.N. (in press). Is parent-child disagreement on child anxiety explained by differences in measurement properties? An examination of measurement invariance across informants and time.  Frontiers in Psychology: Quantitative Psychology and Measurement. 
 
Perlman, G., Gromatsky, M., Salis, K.L. Klein, D.N., & Kotov, R. (in press). Personality correlates of self-injury in adolescent girls: Disentangling the effects of lifetime psychopathology.  Journal of Abnormal Child Psychology.
 
Schweizer, T., Olino, T.M., Dyson, M.W., Laptook, R.S., & Klein, D.N. (in press). Developmental origins of rumination in middle childhood: The roles of early temperament and positive parenting.  Journal of Clinical Child and Adolescent Psychology. 
 
Shankman, S.A., Funkhouser, C.J., Klein, D.N., Davila, J., Lerner, D., & Hee, D. (In press). Reliability and validity of severity dimensions of psychopathology assessed using the Structured Clinical Interview for DSM-5 (SCID).  International Journal of Methods of Psychiatric Research.
 
Speed, B.C., Nelson, B.D., Levinson, A.R., Perlman, G., Klein, D.N., Kotov, R., & Hajcak, G. (in press). Personality and electrocortical response to monetary rewards in adolescent girls.  Biological Psychology.

  2018

Black, S.R., Lerner, M.D., Shirtcliff, E.A., & Klein, D.N. (2018). Patterns of neuroendocrine coupling in 9-year-old children: Effects of body-mass index and life stress.  Biological Psychology 132 , 252-259.

Carlson, G.A., & Klein, D.N. (in press). Frying pan to fire? Commentary on Practitioner Review: Definition, recognition and treatment challenges of irritability in young people.  Journal of Child Psychology and Psychiatry, 59 , 740-743.

Goldstein, B.L., Kotov, R., Perlman, G., Watson, D., & Klein, D.N. (2018). Trait and facet-level predictors of first-onset depressive and anxiety disorders in a community sample of adolescent girls.  Psychological Medicine 48 , 1282-1290.

Kessel, E.M., Nelson, B.D., Kujawa, A., Hajcak, G., Bromet, E., Kotov, R., Carlson, G.A. & Klein, D.N. (2018). Hurricane Sandy-related stress exposure alters the development of neural reactivity to negative stimuli in children.  Child Development, 89 , 339-348.

Kryski, K.R., Olino, T.M., Dyson, M.W., Durbin, C.E., Klein, D.N., & Hayden, E.P. (2018). Associations between observed temperament in preschoolers and parent psychopathology.  Personality and Mental Health 12 , 131-144.

McDonough-Caplan, H., Klein, D.N., & Beauchaine, T.P. (2018). Patterns of growth in depression and conduct problems from elementary school to adolescence among highly vulnerable children and their peers.  Journal of Abnormal Psychology, 127 , 326-337.

Meyer, A., Hajcak, G., Hayden, E., Sheikh, H.I., Singh, S.M., & Klein, D.N. (2018). A genetic variant BDNF polymorphism interacts with hostile parenting to predict error-related brain activity in children and thereby risk for internalizing disorders.  Development and Psychopathology, 30 , 125-141.

Meyer, A., Hajcak, G., Torpey-Newman, D., Kujawa, A., Olino, T.M., Dyson, M., & Klein, D.N. (2018). Early temperamental fearfulness and the developmental trajectory of error-related brain activity.  Developmental Psychobiology, 60 , 224-231.

Nelson, B.D., Infantolino, Z.P., Klein, D.N., Perlman, G., Kotov, R., & Hajcak, G.  (2018). Time-frequency reward-related delta prospectively predicts adolescent-onset depression.  Biological Psychiatry:   Cognitive Neuroscience and Neuroimaging, 3 , 41-49.

Vandermeer, M.R., Sheikh, H.I., Singh, S.S., Klein, D.N., Olino, T.M., Dyson, M.W., Bufferd, S.J., & Hayden, E.P. (2018). The BDNF gene val66met polymorphism and behavioural inhibition in early childhood.  Social Development, 27 , 543-554.

2017

Barrios, C.S., Bufferd, S.J., Klein, D.N., & Dougherty, L.R. (2017). The interaction between parenting and children’s cortisol reactivity at age three predicts increases in children’s internalizing and externalizing symptoms at age six.  Development and Psychopathology, 29 , 1319-1331.

Beauchaine, T.P., & Klein, D.N. (2017). Developmental psychopathology and the Diagnostic and Statistical Manual of Mental Disorders. In T.P. Beauchaine and S.P. Hinshaw (Eds.),  Child and adolescent psychopathology , 3rd ed (pp. 33-67). Hoboken, New Jersey: John Wiley & Sons. 

Craighead, W.E., Klein, D.N., Gillespie, C.F., Ritschel, L.A., & Phillips, K.E. (2017). Depressive disorders. In W.E. Craighead, D.J. Miklowitz, and L.W. Craighead (Eds.),  Psychopathology: History, theory, and diagnosis , 3rd ed (pp. 262-316). Hoboken, N.J.: John Wiley & Sons.

Delaparte. L., Yeh, F.C., Adams, P., Malchow, A., Trivedi, M., Oquendo, M., Deckersbach, T., Ogden, T., Pizzagalli, D., Fava, M., Cooper, C., McInnis, M., Kurian, B., Weissman, M., McGrath, P., Klein, D., Parsey, R., & DeLorenzo, C. (2017). A comparison of structural connectivity in anxious depression versus non-anxious depression.  Journal of Psychiatric Research, 89 , 38-47.

Dougherty, L.R., Barrios, C.S., Carlson, G.A., & Klein, D.N. (2017). Predictors of later psychopathology in young children with disruptive mood dysregulation disorder (DMDD).  Journal of Child and Adolescent Psychopharmacology, 27 , 396-402.

Ethridge, P., Kujawa, A., Dirks, M.A., Arfer, K.B., Kessel, E.M., Klein, D.N., & Weinberg, A. (2017). Neural responses to social and monetary reward in early adolescence and emerging adulthood.  Psychophysiology, 54 , 1786-1799.

Goldstein, B.L., Perlman, G., Kotov, R., Broderick, J.E., Liud, K., Ruggero, C., & Klein, D.N. (2017). Etiologic specificity of waking cortisol: Links with maternal history of depression and anxiety in adolescent girls.  Journal of Affective Disorders, 208 , 103-109.

Gromatsky, M., Waszczuk, M., Perlman, G., Salis, K., Klein, D. N., & Kotov, R. (2017). The role of parental psychopathology and personality in adolescent non-suicidal self-injury.  Journal of Psychiatric Research 85 , 15-23.

Jin, J., Narayanan, A., Perlman, G., Luking, K., DeLorenzo, C., Hajcak, G., Klein, D.N., Kotov, R., & Mohanty, A. (2017). Orbitofrontal cortex activity and connectivity predict future depression symptoms in adolescence.  Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 2 , 610-618.

Kann, S.J., O’Rawe, J.F., Huang, A.S., Klein, D.N., & Leung, H.-C. (2017). Preschool negative affect impacts activity and connectivity of the fusiform face area and amygdala in later childhood.  Social, Cognitive, and Affective Neuroscience, 12 , 1511-1519.

Kessel, E.M., Allmann, A.E.S., Goldstein, B., Finsaas, M., Dougherty, L.R., Bufferd, S., Carlson, G.A., & Klein, D.N. (2017). Predictors, correlates, and outcomes of childhood primary enuresis.  Journal of the American Academy of Child and Adolescent Psychiatry, 56 , 250-257.

Kessel, E.M., Kujawa, A.J., Dougherty, L.R., Hajcak, G., Carlson, G.A., & Klein, D.N. (2017). Neurophysiological processing of emotion in children of mothers with a history of depression: The moderating role of preschool persistent irritability.  Journal of Abnormal Child Psychology, 45, 1599-1608

Kessel, E.M., Kujawa, A.G., Goldstein, B.L., Hajcak, G., Bufferd, S.J., Dyson, M.D., & Klein, D.N. (2017). Behavioral observations of positive and negative valence systems in early childhood predict physiological measures of emotional processing three years later.  Journal of Affective Disorders, 216, 70-77

Klein, D.N., & Black, S. R. (2017). Persistent depressive disorder.  In R.J. DeRubeis & D.R. Strunk (Eds.),  Oxford Handbook of Mood Disorders (pp. 227-237). New York: Oxford University Press.

Klein, D.N., & Finsaas, M.C. (2017). The Stony Brook Temperament Study: Early antecedents and pathways to emotional disorders.  Child Development Perspectives, 11, 257-263.

Klein, D.N., Goldstein, B.L., & Finsaas, M. (2017).  Depressive disorders.  In T.P. Beauchaine and S.P. Hinshaw (Eds.),  Child and Adolescent Psychopathology, 3rd ed. (pp. 610-641). Hoboken, New Jersey: John Wiley & Sons. 

Kopala-Sibley, D.C., Dougherty, L.R., Dyson, M.W., Laptook, R.S., Olino, T.M., Bufferd, S.J., & Klein, D.N. (2017). Early childhood cortisol reactivity moderates the effects of parenting on the development of children’s temperament in early childhood.  Developmental Science, 20(3).

Kopala‐Sibley, D. C., Hayden, E. P., Singh, S. M., Sheikh, H. I., Kryski, K. R., & Klein, D. N. (2017). Gene‐environment correlations in the cross‐generational transmission of parenting: Grandparenting moderates the effect of child 5‐HTTLPR genotype on mothers' parenting.  Social Development, 26, 724-739.

Kopala-Sibley, D.C., Jelinek, C., Allmann, A.E.S., & Klein, D.N. (2017). Parental depressive history, parenting styles, and child psychopathology over six years: The contribution of each parent’s depressive history to the other’s parenting styles.  Development and Psychopathology, 29, 1469-1482.

Kopala-Sibley, D.C., & Klein, D.N. (2017). Depressive disorders: Presentation, classification, developmental trajectories, and course. In N. Cohen (Ed).  Public Health Perspectives on Depressive Disorders (pp. 13-39).  Baltimore: Johns Hopkins University Press.

Kopala-Sibley, D.C., & Klein, D.N. (2017). Distinguishing types of social withdrawal in children: Internalizing and externalizing outcomes of conflicted shyness versus social disinterest across childhood.  Journal of Research in Personality, 67, 27-35.

Kopala-Sibley, D.C., Klein, D.N., Perlman, G., & Kotov, R. (2017). Self-criticism and dependency in female adolescents: Prediction of first onsets and disentangling the relationships between personality, life stress, and internalizing psychopathology.  Journal of Abnormal Psychology, 126, 1029-1043.

Kotelnikova, Y., Olino, T.M., Klein, D.N., Mackrell, S.V.M., & Hayden, E.P. (2017). Higher- and lower-order factor analyses of the Temperament in Middle Childhood Questionnaire.  Assessment, 24, 1050-1061.  

Kujawa, J., Kessel, E., Carroll, A., Arfer, K., & Klein, D.N. (2017). Social processing in early adolescence: Associations between neurophysiological, self-report, and behavioral measures.  Biological Psychology128, 55-62.

Laws, H. B., Constantino, M. J., Sayer, A. G., Klein, D. N., Kocsis, J. H., Manber, R., Markowitz, J.C., Rothbaum, B. O., Steidtmann, D., Thase, M. E., & Arnow, B. A. (2017). Convergence in patient-therapist therapeutic alliance ratings and its relation to outcome in chronic depression treatment.  Psychotherapy Research, 27(4).

Le, T.M., Borghi, J.A., Kujawa, A.J., Klein, D.N., & Leung, H.-C. (2017). Alterations in visual cortical activation and connectivity with prefrontal cortex during working memory updating in major depressive disorder.  Neuroimage: Clinical14, 43-53

Mackin, D. M., Perlman, G., Davila, J., Kotov, R., & Klein, D. N. (2017). Social support buffers the effect of interpersonal life stress on suicidal ideation and self-injury during adolescence.  Psychological Medicine, 47, 1149-1161.

Meyer, A., Danielson, C., Danzig, A.P., Bhatia, V., Black, S.R., Bromet, E., Carlson, G.A., Hajcak, G., Kotov, R., & Klein, D.N. (2017). Neural biomarker and early temperament predict increased internalizing symptoms after a natural disaster.  Journal of the American Academy of Child and Adolescent Psychiatry, 56, 410–416

Meyer, A., Hajcak, G., Glenn, C.R., Kujawa, A.J., & Klein, D.N. (2017). Error-related brain activity is related to aversive potentiation of the startle response in children.  Emotion, 17, 487-496.

Parisette, A., Bufferd, S.J., & Klein, D.N. (2017). Parental predictors of children’s shame and guilt at age 6 in a multi-method, longitudinal study.  Journal of Clinical Child and Adolescent Psychology, 46, 721-731.

Qiu, T., Klonsky, E. D., & Klein, D. N. (2017). Hopelessness predicts suicide ideation but not attempts: A 10‐year longitudinal study.  Suicide and Life-Threatening Behavior, 47, 718-722.

Rappaport, B. I., Pagliaccio, D., Pine, D. S., Klein, D. N., Jarcho, J. M. (2017). Discriminant validity, diagnostic utility, and parent-child agreement on the Screen for Child Anxiety Related Emotional Disorders (SCARED) in treatment- and non-treatment-seeking youth.  Journal of Anxiety Disorders, 51, 22-31.

Schuler, K. L., Ruggero, C. J., Goldstein, B., Perlman, G., Klein, D., & Kotov, R. (2017). Diurnal cortisol interacts with stressful events to prospectively predict depressive symptoms in adolescent girls.  Journal of Adolescent Health, 61, 767-772.

Shankman, S.A., Gorka, S.M., Katz, A.C., Klein, D.N., Markowitz, J.C., Arnow, B.A., Manber, R., Rothbaum, B.O., Thase, M.E., Schatzberg, A.F., Keller, M.B., Trivedi, M.H., & Kocsis, J.H. (2017). Side effects to antidepressant treatment in patients with depression and comorbid panic disorder.  Journal of Clinical Psychiatry, 78, 433-440.

Stumper, A., Danzig, A.P., Dyson, M.W., Olino, T.M., Carlson, G.A., & Klein, D.N. (2017). Parents’ behavioral inhibition moderates association of preschoolers’ BI with risk for age 9 anxiety disorders.  Journal of Affective Disorders210, 35-42.

2016

Allmann, A., Kopala-Sibley, D.C., Klein, D.N. (2016). Preschoolers’ psychopathology and temperament predict mothers’ later mood disorders. Journal of Abnormal Child Psychology, 44, 421-432. 

Carlson, G.A., Danzig, A.P., Dougherty, L.R., Bufferd, S.J., & Klein, D.N. (2016). Loss of temper and irritability: The relationship to tantrums in a community and clinical sample. Journal of Child and Adolescent Psychopharmacology, 26, 114-122. 

Constantino, M. J., Laws, H. B., Coyne, A. E., Greenberg, R. P., Klein, D. N., Manber, R., ... & Arnow, B. A. (2016). Change in patients’ interpersonal impacts as a mediator of the alliance-outcome association in treatment for chronic depression. Journal of Consulting and Clinical Psychology, 84, 1135-1144. 

Dougherty, L. R., Smith, V. C., Bufferd, S. J., Kessel, E. M. Carlson, G. A., & Klein, D. N. (2016). Disruptive mood dysregulation disorder at the age of 6 years and clinical and functional outcomes 3 years later. Psychological Medicine, 46, 1103-1114. 

Furukawa, T.A., Schramm, E., Weitz, E.S., Salanti, G., Efthimiou, O., Michalak, J., Watanabe, N., Cipriani, A., Keller, M.B., Kocsis, J.H., Klein, D,N., & Cuijpers, P. (2016). Cognitive-Behavioral Analysis System of Psychotherapy (CBASP), drug or their combination: Differential therapeutics for persistent depressive disorder: A study protocol of an individual participant data network meta-analysis. BMJ Open, 6, e011769. 

Goldstein, B.L., Shankman, S.A., Kujawa, A.J., & Klein, D.N. (2016). Developmental changes in electroencephalographic frontal asymmetry in young children at risk for depression. Journal of Child Psychology and Psychiatry, 57, 1075-1082. 

Huang, A., Klein, D.N., & Leung, H.-C. (2016). Load-related brain activity predicts spatial working memory performance in children aged 9-12. Developmental Cognitive Neuroscience, 17, 1-9. 

Johnson, V. C., Olino, T. M., Klein, D. N., Dyson, M. W., Bufferd, S. J., Durbin, C. E., Dougherty, L.R., & Hayden, E. P. (2016). A longitudinal investigation of predictors of the stability of behavioural inhibition in early childhood. Journal of Research in Personality, 63, 51-61. 

Kessel, E.M., Dougherty, L.R., Kujawa, A.J., Hajcak, G., Carlson, G.R., & Klein, D.N. (2016). Longitudinal associations between preschool Disruptive Mood Dysregulation Disorder symptoms and neural reactivity to monetary reward during preadolescence. Journal of Child and Adolescent Psychopharmacology, 26, 131-137. 

Kessel, E.M., & Klein, D.N. (2016). Depressivity and anhedonia. In V. Zeigler-Hill & D. K. Marcus (Eds.), The dark side of personality (pp.307-324). Washington, DC: American Psychological Association. 

Kessel, E. M., Meyer, A., Hajcak, G., Dougherty, L. R., Torpey-Newman, D. C., Carlson, G. A., & Klein, D. N. (2016). Transdiagnostic factors and pathways to multifinality: The error-related negativity predicts whether preschool irritability is associated with internalizing versus externalizing symptoms at age 9. Development and Psychopathology, 28, 913-926. 

Klein, D.N., & Kotov, R. (2016). Persistence of depression in a 10-year prospective study: Evidence for a qualitatively distinct subtype. Journal of Abnormal Psychology, 125, 337-348. 

Kopala-Sibley, D.C., Danzig, A.P., Kotov, R., Bromet, E.J., Carlson, G.A., Olino, T.M., Bhatia, V., Black, S.R., & Klein, D.N. (2016). Negative emotionality and its facets moderate the effects of exposure to Hurricane Sandy on children's post-disaster depression and anxiety symptoms. Journal of Abnormal Psychology, 125, 471-481.

Kopala-Sibley, D.C., Kotov, R., Bromet, E.J., Carlson, G.A., Danzig, A.P., Black, S.R., & Klein, D.N. (2016). Personality diatheses and Hurricane Sandy: Effects on post-disaster depression. Psychological Medicine, 4, 865-875. 

Kotelnikova, Y., Olino, T.M., Klein, D.N., Kryski, K.R., & Hayden, E.P. (2016). Higher- and lower-order factor analyses of the Children’s Behavior Questionnaire in early and middle childhood. Psychological Assessment, 28, 92-108. 

Kujawa, A., Hajcak, G., Danzig, A.P., Black, S.R., Bromet, E.J., Carlson, G.A., Kotov, R., & Klein. D. N. (2016). Neural reactivity to emotional stimuli prospectively predicts the impact of a natural disaster on psychiatric symptoms in children . Biological Psychiatry, 80, 381–389. 

Liu, K., Ruggero, C.J., Goldstein, B., Klein, D.N., Perlman, G., Broderick, J., & Kotov, R. (2016). Elevated cortisol in adolescent offspring of parents with posttraumatic stress disorder. Journal of Anxiety Disorders, 40, 37-43 . 

McCullough, Jr., J.P., Clark, S.W., Klein, D.N., & First, M.B. (2016). A procedure to graph the quality of psychosocial functioning affected by symptom severity. American Journal of Psychotherapy, 70, 222-231. 

McCullough, Jr., J.P., Clark, S.W., Klein, D.N., & First, M.B. (2016). Introducing a clinical course graphing scale for DSM-5 disorders. American Journal of Psychotherapy, 70, 383-392  

Nelson, B. D., Perlman, G., Klein, D. N., Kotov, R., & Hajcak, G. (2016). Blunted neural response to rewards as a prospective predictor of the development of depression in adolescent girls. American Journal of Psychiatry, 173, 1223-1230. 

Salis, K. L., Bernard, K., Black, S. R., Dougherty, L. R., & Klein, D. (2016). Examining the concurrent and longitudinal relationship between diurnal cortisol rhythms and conduct problems during childhood. Psychoneuroendocrinology, 71, 147-154. 

Speed, B.C., Nelson, B.D., Auerbach, R.P., Klein, D.N., & Hajcak, G. (2016). Depression risk and electrocortical reactivity during self-referential emotional processing in 8-14 year old girls. Journal of Abnormal Psychology, 125, 607-619. 

Weinberg, A., Meyer, A., Hale-Rude, E., Perlman, G., Kotov, R., Klein, D.N., & Proudfit, G. (2016). Error-related negativity and sustained threat: Conceptual framework and empirical evaluation in an adolescent sample. Psychophysiology, 53, 372-385.

Current Research Support:

National Institute of Mental Health (RO1 MH 069942), "Temperamental emotionality in preschoolers and depression risk."
2004 - 2019. $6,789,330 (direct costs)
Principal Investigator (Co-Is: Gabrielle Carlson, Greg Hajcak, Joanne Davila, Thomas Olino)  

National Institute of Mental Health Grant R56 (MH117116) “Gene expression and vulnerability to depression." 
2018-2020.  $940,865 (direct costs)
Multiple Principal Investigators (Klein and Kotov)

National Institute of Occupational Safety and Health (U02 OH011321), “Personality-informed care model for 9/11-related comorbid conditions.”
2016-2021. $2,283,267 (direct costs)
Co-Investigator (PI: Roman Kotov) 

National Institute of Mental Health (R21 MH108766) “Targeting biomarkers of risk for depression and anxiety through a parenting intervention”
2016-2018.  $275,000 (direct costs).
Co-Investigator (PIs: Kristin Bernard and Greg Hajcak). 

National Institute of Mental Health (RO1 MH 097767), “Trajectories of reward sensitivity and depression across adolescence”.
2018-2022. $2,588,487 (direct costs)
Co-Investigator (PI: Brady Nelson) 

National Institute of Mental Health (R21 MH111999), “Role of Top-down factors in threat perception in anxiety”.
2017-2019 .  $275,000 (direct costs)
Co-Investigator (PI: Aprajita Mohanty)

National Institute of Mental Health (R03 MH110637), “A developmental exploration of the RDoC social processes domain: Mapping brain-behavior trajectories“.
2016-2018.   $100,000 (direct costs)
Co-Investigator (PI: Andrew Belden)

Primary Mentor on Graduate Fellowship Awards:

National Institute of Mental Health Predoctoral National Research Service Award to Ellen M. Kessel

National Science Foundation Graduate Research Fellowship to Megan Finsaas 

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