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AGEP-T FRAME Fellow: Moises Guardado



Moises Guardado

Graduate Student, Stony Brook University


Specialty: Cancer Chemotherapeutics & Cancer Metabolism

AGEP-T FRAME Research Mentors: Dr. Paul Bingham, Dr. Zuzana Zachar                   

Email: Moises.Guardado@stonybrook.edu


was born in El Salvador and came to the US during high school. After some time I made my way from Suffolk Community College to Stony Brook University to get a B.S in Biochemistry. I continued on to obtain an M.S in Biochemistry and Cell Biology at Stony Brook, and sedimented my status as a seawolf (admittedly not a sports fan) now pursuing a PhD in Genetics at Stony Brook. I have been part of the CIE as a BD, W. Burghardt Turner, and AGEP-T FRAME fellow.

Seminar Topic: Probing the metabolic state of cancer cell and its role in metastasis.

Description: The ability of cancer cells to migrate from the initial tumor to distant sites (metastasis) is one the most deleterious aspects of cancer progression and prognosis. One of the hallmarks of metastasis is the transition from stationary differentiated (epithelial) cells to motile stromal-like (mesenchymal) cells, this has been termed Epithelial to Mesenchymal Transition (EMT). The contribution of the metabolic state of the cells to the EMT is poorly understood. The microenvironment and its effects to the metabolic state of cells plays an important role in the cells' ability on invade and travel to distant sites.