AGEP-T FRAME Fellow: Jinelle Wint
Graduate Student, Stony Brook University
Department of Molecular & Cellular Biology
AGEP-T FRAME Research Mentor: Dr. Howard Sirotkin
I am originally from Ft. Lauderdale, FL. I received my B.S. in Biology and Studio Art from the University of Miami. As a master's student, I worked with Dr. J. Peter Gergen conducting research that focuses on gene transcription in Drosophila embryogenesis. In my free time, I enjoy traveling, photography and ceramics. I was admitted into the Molecular and Cellular Biology Doctoral Program in the Fall of 2014.
Seminar Title: Zebrafish as a model for Parkinson's Disease
Description: Parkinson's disease is estimated to affect over 1 million people in the US. The disease's more notable symptoms are degenerative motor functions. About 10-15% of those affected have certain inherited genetic mutations that can often lead to the disease. One of these mutated proteins is called Leucine Repeat Rich Kinase 2 or LRRK2. I'm using CRISPR/Cas 9 to knockout this gene in the zebrafish to explore the mechanisms of the mutation.