All laboratory procedures require a safety protocol or Standard Operating Procedure (SOP). Such procedures must include materials hazards, information of equipment used, safety controls (i.e. engineering controls, PPE) required, emergency procedures, disposal of waste, and precautions for handling materials.
- SOPs must be reviewed annually
- SOPs must be review under the following circumstances:
- Reagents in protocol are removed or substituted
- Quantity of a chemical is changed by ≥ 25%
- Failure of equipment (e.g. fume hood, clamp, instrumentation)
- Unexpected test results, determine how new results affect safety procedures
- When laboratory workers become ill, detect chemical odor, suspect exposure, or expect safeguard failure