Ken A. Dill
Professor. Director of the Laufer Center for Physical & Quantitative Biology. Statistical physics of biological molecules and cells. We model proteins, water, cell networks, dynamics of small systems, and we develop methods for computer-based drug discovery.

Dale Drueckhammer
Professor. Computer-based design and synthesis of receptors and sensors for biomolecules. Design and synthesis of enzyme inhibitors. Enzyme reaction mechanisms

Frank Johnson
Professor. Synthesis of viral enzyme inhibitors. Chemical aspects of genetic toxicology. New organo-alkali synthetic chemi

Jeffrey Lipshultz
Assistant Professor. Organic and organometallic photochemistry for development of catalytic reaction platforms aimed at valorization of feedstock chemicals and derivatization of bioactive molecules. Selective protein and peptide functionalization.

Iwao Ojima
Distinguished Professor. Design, synthesis, and structure-activity relationships of medicinally-active compounds, especially for the drug design and discovery of anticancer agents and antimicrobials. Development of new and efficient methods for the synthesis of biologically active compounds of medicinal interests.

Nicole Sampson
Distinguished Professor. Bioorganic chemistry and mechanistic enzymology. Investigation of the structure and function of cholesterol oxidase protein-membrane interactions, and its relationship to Mycobacterium tuberculosis pathogenesis. Synthesis of peptides and polymers to probe the role of ADAM proteins in mammalian fertilization.

Peter Tonge
Distinguished Professor. Biological chemistry and enzymology. Quantitating substrate strain in enzyme-catalyzed reactions using vibrational and NMR spectroscopies. Rational drug design. Pathogenesis of Mycobacterium tuberculosis. Structure-function studies of fluorescent proteins.