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Ken A. Dill Professor. Director of the Laufer Center for Physical & Quantitative Biology. Statistical
physics of biological molecules and cells. We model proteins, water, cell networks,
dynamics of small systems, and we develop methods for computer-based drug discovery.
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Dale Drueckhammer Professor. Computer-based design and synthesis of receptors and sensors for biomolecules.
Design and synthesis of enzyme inhibitors. Enzyme reaction mechanisms
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Frank Johnson Professor. Synthesis of viral enzyme inhibitors. Chemical aspects of genetic toxicology.
New organo-alkali synthetic chemi
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Jeffrey Lipshultz Assistant Professor. Organic and organometallic photochemistry for development of catalytic reaction platforms
aimed at valorization of feedstock chemicals and derivatization of bioactive molecules.
Selective protein and peptide functionalization.
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Iwao Ojima Distinguished Professor. Design, synthesis, and structure-activity relationships of
medicinally-active compounds, especially for the drug design and discovery of anticancer
agents and antimicrobials. Development of new and efficient methods for the synthesis
of biologically active compounds of medicinal interests.
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Nicole Sampson Distinguished Professor. Bioorganic chemistry and mechanistic enzymology. Investigation
of the structure and function of cholesterol oxidase protein-membrane interactions,
and its relationship to Mycobacterium tuberculosis pathogenesis. Synthesis of peptides
and polymers to probe the role of ADAM proteins in mammalian fertilization.
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Peter Tonge Distinguished Professor. Biological chemistry and enzymology. Quantitating substrate
strain in enzyme-catalyzed reactions using vibrational and NMR spectroscopies. Rational
drug design. Pathogenesis of Mycobacterium tuberculosis. Structure-function studies
of fluorescent proteins.
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