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A comparison
of flow through monoleaflet and bileaflet mechanical heart valves utilizing in
vitro Digital Particle Imaging Velocimetry and Computational Fluid Dynamics Jonathan Birnbaum, Great Neck North High School, Great Neck; Yared Alemu, Sagi Raz, Danny Bluestein, Department of Biomedical Engineering, Stony Brook University | |||
Although
Mechanical Heart Valves (MHVs) are unrivaled in terms of durability, their success
is still limited due to thromboembolic, or clot inducing, complications. It is
hypothesized that thromboembolic complications are initiated and maintained mostly
by the non-physiologic flow patterns through the valve that induce platelet activation
and aggregate them in the shed vortices generated in the valve's wake to produce
small blood clots (thromboemboli). The popular bileaflet design has recently come
under scrutiny for its relatively high rates of thromboembolic complications,
leading to a renewed interest in the slightly older monoleaflet design. In this
study, the leading St. Jude Medical bileaflet MHV was compared with a Medtronic
Hall monoleaflet design. A non-invasive in vitro technique, Digital Particle Imaging
Velocimetry (DPIV), was utilized to measure two dimensional displacement and velocity
vector fields of fluid moving distal to a valve in a recirculation flow loop driven
by peristaltic and pulsatile flow pumps. Computational Fluid Dynamics (CFD) was
also employed in two dimensional geometries of the two valves to compare with
the DPIV results. The results of the measured flow fields indicate high levels
of shear stresses in the bileaflet valve design, generated by the jets during
flow passage through the valve major and minor orifices, indicative of flow areas
where platelet activation may occur. Distinct shed vortices were measured in the
wake of the bileaflet valve, and a large recirculation zone characterized the
flow field distal to the monoleaflet valve. Shear stress history of distinct particle
trajectories were computed in both the CFD and DPIV, and are to be quantified
in order to predict platelet activation levels within 'hot spot' regions in the
valve flow fields. A novel approach was also applied for the DPIV measurements
to construct a three dimensional presentation of the flow fields past the valves.
Ultimately, results of this study may contribute to the continuous design modifications
of the MHVs with the intent of minimizing post operation complications. | ||||
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