Graduate Bulletin

Spring 2018

Faculty of the Molecular and Cellular Biology Graduate Program

Distinguished Professors

Benach, Jorge L.2, Ph.D., 1972, Rutgers University: Host response to bacterial infections.

Citovsky, Vitaly1, Ph.D., 1987, Hebrew University, Israel: Nuclear targeting and intercellular communication in plants.

Grollman, Arthur, P.4, M.D., 1959, John Hopkins University: DNA damage, mutagenesis and repair; chemical carcinogenesis.

Lennarz, William, J.1, Ph.D., 1959, University of Illinois: Biosynthesis and function of glycoproteins in cell-cell interactions.

London, Erwin1, Ph.D., 1979, Cornell University: Membrane protein structure/translocation/folding Structure and function of sphingolipid/cholesterol rafts in membranes.

Sternglanz, Rolf1, Ph.D., 1967, Harvard University: Chromatin structure and function in yeast;histone modifying enzymes.

Wimmer, Eckard2, Ph.D., 1962, University of Gottingen, Germany: RNA virus genetics, replication, and pathogenicity; cellular virus receptors; whole viral genome synthesis; development of novel vaccines.


Bingham, Paul M.1, Ph.D., 1979, Harvard University: Genetic control of development and gene expression in animals.

Bogenhagen, Daniel F.4, M.D., 1977, Stanford University: Mitochondrial DNA; Mitochondrial proteomics.

Brown, Deborah1, Ph.D., 1987, Stanford University: Cholesterol/sphingolipid-rich membrane domains; role in endocytosis.

Bynum, David R.1, Ph.D., 1981 Dartmouth College: Director, Long Island Group Advancing Science Education, Stony Brook University.

Chen, Wen-Tien8, Ph.D., 1979, Yale University: Proteases and integrins in cancer invasion, metastasis, and angiogenesis.

Dean, Neta1, Ph.D., 1988, University of California, Los Angeles: Protein glycosylation, fungal cell wall biosynthesis; fungal pathogenesis.

Demple, Bruce4, Ph.D., Defining new repair pathways for oxidative DNA damage in the nucleus and the mitochondria of mammalian cells.

Deutsch, Dale1, Ph.D., 1972, Purdue University: Metabolism and uptake of the endocannabinoids (anandamide and 2-AG).

Frohman, Michael A.4, M.D./Ph.D., 1986, University of Pennsylvania: Mammalian signal transduction, development, vesicular trafficking, mitochondrial fusion diabetes.

Furie, Martha5, Ph.D., 1980, Rockefeller University: Interactions among pathogenic bacteria, endothelium, and leukocytes.

Futcher, Bruce2, Ph.D., 1981 Oxford University; Cell cycle control, microarrays, genomics.

Gergen, J. Peter1, Ph.D., 1982, Brandeis University: Pattern information and the regulation of gene expression during Drosophiladevelopment.

Ghebrehiwet, Berhane8, D.V.M./D.Sc., 1974, University of Paris, France: Biochemistry; Role of complement C1q receptors during infection and inflammation.

Halegoua, Simon3, Ph.D., 1978, Stony Brook University: Control of the neuronal phenotype and survival by growth factors using biochemical, molecular and cell biological approaches.

Haltiwanger, Robert1, Ph.D., 1986, Duke University: Glycobiology; role of glycosylation in signal transduction and development. Hannun, Yusuf, 1,7, MD , 1, Bioactive lipids in cancer pathogenesis and therapeutics.

Hayman, Michael2, Ph.D., 1973, Institute for Medical Research, England: Viral/cellular oncogenes; differentiation of erythroid cells.

Hearing, Patrick2, Ph.D., 1980, Northwestern University: Adenovirus-host cell interactions, adenovirus assembly and vectors for gene therapy.

Hollingsworth, Nancy1, Ph.D., 1988, University of Washington, Seattle: Regulation of meiotic recombination in yeast. Katz, Eugene2, 14, Ph.D., 1969, University of Cambridge, England: Genetics/development in cellular slime molds.

Konopka, James2, Ph.D., 1985 University of California, Los Angeles: Signal transduction, morphogenesis, and genetics of pathogenic fungi.

Levine, Joel M.3, Ph.D., 1980, Washington University: Cell-surface molecules of the developing nervous system.

Lin, Richard6, M.D., 1988, University of California, San Francisco: Physiology of phosphoinositide 3-kinase signaling

Ma, Yupo12 M.D., Jinan University, Ph.D., University of South Alabama: Leukemic stem cells, stem cell therapy and tissue repair.

Mackow, Erich R.2, Ph.D., 1984, Temple University: Viral regulation of cell signaling responses. Hantavirus, Influenza, Dengue and Rotavirus pathogenesis.

Malbon, Craig C.4, Ph.D., 1976, Case Western Reserve University: Signal transduction and gene regulation in differentiation and development: Roles of G-proteins.

Marcu, Kenneth B.1, Ph.D., 1975, Stony Brook University: NF-kappaB kinase signaling in stress, immunity and cancer; mechanisms of action of AID in adaptive immune responses.

McLaughlin, Stuart6, Ph.D., 1968, University of British Columbia, Canada: Calcium/phospholipid second messenger system. Miller, Todd W.6, Ph.D., 1989, Rockefeller University: The regulation and substrate specificity of tyrosine kinases.

Moll, Ute M.5, M.D., 1985, Ulm, Germany: Function/regulation of the p53 gene family in apoptosis and cancer.

Neiman, Aaron1, Ph.D., 1994, University of California, San Francisco: Vesicle trafficking and intracellular signaling in yeast.

Obeid, Lina, 7, Ph.D Bioactive lipids in Inflammation, Aging and Cancer.

Powers, Scott13, Ph.D., 1982, Columbia University: Genetic basis of cancer.

Reich, Nancy L.2, Ph.D., 1983, Stony Brook University: Signal transduction and gene expression in response to cytokines and virus.

Scarlata, Suzanne6, Ph.D., 1984, University of Illinois: Structure/function studies of G proteins and effectors.

Schechter, Nisson1, Ph.D., 1971, Western Michigan University: Homeobox and filament proteins in neuronal differentiation, growth and regeneration.

Shroyer, Kenneth5, Ph.D. 1983, M.D. 1987, University of Colorado. Cancer biomarkers as diagnostic adjuncts in cervical pathology and cytopathology; cervical cancer and HPV.

Simon, Sanford R.1,5, Ph.D., 1967, Rockefeller University: Proteinases and their inhibitors in invasiveness inflammation and tumor metastasis; Inhibition of bacterial metalloproteinases.

Smith, Steven O.1, Ph.D., 1985, University of California, Berkeley: Structure and function of membrane proteins.

Steigbigel, Roy T.8, M.D., 1966, University of Rochester: Immune dysfunction induced by HIV infection.

Simmerling, Carlos9, Ph.D. 1994, University of Illinois at Chicago: Development of tools for efficient and simulation of chemical systems and using them to study the structure and dynamics of molecules involved in biological processes.

Thanassi, David G.2, Ph.D., 1995 University of California at Berkeley: Virulence factors of pathogenic bacteria.

Thomson-Carino5, Patricia, Ph.D., The evolution of molecular and cellular changes during the development of colorectal and breast cancer

Thomsen, Gerald H.1, Ph.D., 1988, Rockefeller University: Emproyic development mechanisms and their evolution.

Tsirka, Styliani-Anna4, Ph.D., 1989, University of Thessaloniki, Greece: Neuronal-microglial interactions in the physiology and pathology of the central nervous system.

Tonge, Peter J.4, Ph.D., 1986, University of Birmingham, England: Chemical biology and spectroscopy; Enzyme mechanisms, rational inhibitor design and antibacterial drug discovery; Fluorescent and light-activated proteins.

Van Nostrand, William E.17, Ph.D. 1985, University of California at Irvine: Molecular pathogenic mechanisms in cerebrovascular pathology of Alzheimer’s disease and related disorders.

White, Thomas6, Ph.D., 1994, Harvard University: Molecular biology and physiology of gap junction channels.

Wollmuth, Lonnie3, Ph.D., 1992 University of Washington: Molecular mechanisms regulating excitatory synaptic transmission in the brain.

Yang, Vincent W., Ph.D., Princeton University; 1984, M.D., Rutgers Robert Wood Johnson Medical School: Mammalian stem cell biology and oncognesis.

Associate Professors

Boon, Elizabeth M.9, Ph.D., 2003, California Institute of Technology: Nitric oxide signaling in bacteria.

Bowen, Mark6, Ph.D., 1998, University of Illinois, Chicago: Molecular recognition at the synapse.

Cao, Jian8, M.D., 1986, Zhengzhou University School of Medicine; M.S., 1992, Peking Union Medical College/Chinese Academy of Medical Sciences: Cancer invasion/metastasis and anti-cancer drug discovery.

Carpino, Nicholas6, Ph.D., 1997, Stony Brook University: Positive and negative regulation of T cell receptor signaling.

Carrico, Isaac9, Ph.D., 2003, California Institute of Technology: Site-specific protein labeling; glycoproteins.

Chen, Emily4, Ph.D., 2002, University of California, San Diego: identifying determinants of breast cancer metastasis and mass spectrometrybased proteomics.

Colognato, Holly4, Ph.D., 2000, Rutgers University: Exracellular matrix in the brain; roles during development and during neurodegeneration.

Czaplinski, Kevin1, Ph.D., 1999, UMDNJ-Robert Wood Johnson Medical School: Post transcriptional control of gene expression in the nervous system.

Fleit, Howard B.5, Ph.D., 1980, New York University: Leukocyte Fc receptors; macrophage differentiation.

Garcia-Diaz, Miguel4, Ph. D., 2003, UAM University (Madrid, Spain): DNA repair and mitochondrial gene expression.

Ghazizadeh, Soosan10, Ph.D., 1994, Stony Brook University: Epithelial stem cell biology; skin bioengineering and gene therapy.

Holdener, Bernadette1, Ph.D., 1990, University of Illinois: The role of protein folding and O-fucosylation during embryonic development and stem cell differentiation

Ju, Jingfang8, Ph.D., 1996, University of Southern California: The mechanism of translational control mediated by non-coding RNAs in cancer.

Karzai, Wali1, Ph.D. 1995, Johns Hopkins University: Post-transcriptional Regulation of Gene Expression

Kernan, Maurice3, Ph.D., 1990, University of Wisconsin: Genetics of touch and hearing in Drosophila; ciliogenesis and ciliarysignaling.

Kew, Richard R.5, Ph.D, 1986, Stony Brook University: Role of complement activation and leukocyte chemotaxis in inflammation.

Krug, Laurie6, Ph.D., 2001, Emory University: Virus-host interactions during chronic gammaherpesvirus infection.

Leatherwood, Janet2, Ph.D., 1993, Johns Hopkins University: Cell-cycle control and DNA replication; fission yeast molecular biology. Lyman, Harvard1, Ph.D., 1960, Brandeis University: Photocontrol of chloroplast development.

McKinnon, David3, Ph.D., 1987, John Curtin School of Medical Research, Australia: Molecular physiology of sympathetic neurons and cardiac muscle.

Moriya, Masaaki4, Ph.D. 1981, Nagoya University, Japan: Cellular responses to DNA damage.

Martinez, Luis A.5, PhD, understanding how alterations in the p53 gene contribute to the development of cancer.

Prives, Joav4, Ph.D., 1968, McGill University, Canada: Cytoskeletal membrane interactions in muscle cells.

Quitschke, Wolfgang7, Ph.D., 1983, Stony Brook University: Gene regulation of proteins associated with neurodegenerative diseases.

Rebecchi, Mario J.8, Ph.D., 1984, New York University: Phospholipases and signal transduction.

Schärer, Orlando D.4,9, Ph.D., 1996, Harvard University: Chemistry and biology of DNA damage and repair.

Seeliger, Markus4, Ph.D., 2003, Cambridge University: Function and mechanism of protein kinases and ubiquitin ligases.

Simmerling, Carlos9, Ph.D. 1994, University of Illinois at Chicago: Development of tools for efficient and simulation of chemical systems and using them to study the structure and dynamics of molecules involved in biological processes.

Sirotkin, Howard3, Ph.D., 1996, Albert Einstein College of Medicine: Vertebrate neural development and patterning.

Spector, Illan6, Ph.D., 1967, University of Paris, France: Neuronal differentiation and microfilaments.

Spitzer, Eric D.5, M.D./Ph.D., 1985, Johns Hopkins University: Molecular biology of Cryptococcus neoformans.

Takemaru, Ken-Ichi4, Ph.D., 1997, The Graduate University for Advanced Studies, Japan: Wnt signaling in development and disease. Thanassi, David G.2, Ph.D.,1995 University of California at Berkeley: Virulence factors of pathogenic bacteria.

Thomsen, Gerald H.1, Ph.D., 1988, Rockefeller University: Emproyic development mechanisms and their evolution.

Tsirka, Styliani-Anna4, Ph.D., 1989, University of Thessaloniki, Greece: Neuronal-microglial interactions in the physiology and pathology of the central nervous system.

van der Velden, Adrianus6, Ph.D., 2000, Oregon Health and Science University: The mammalian T cell response to Salmonella enterica serovar Typhimurium.

Wang, Hsien-yu6, Ph.D., 1989, Stony Brook University: Wnt/Frizzled and G-protein signal transduction in development. White, Thomas6, Ph.D., 1994, Harvard University: Molecular biology and physiology of gap junction channels.

Zieve, Gary5, Ph.D., 1977, Massachusetts Institute of Technology: Assembly/transport of snRNP particles.

Zong, Wei-Xing2, Ph.D., 1999, Univeristy of Medicine & Dentistry of New Jersey: Molecular regulation of apoptotic and necrotic cell death.

Assistant Professors

Aguirre, Adan9Adan4, Ph.D., 2002, Centro de Investigacion y de Estudios Avanzados IPN, Mexico: Endogenous NG2 progenitor cells as cell-based replacement for a variety of brain pathologies

Michael Airola1, Ph.D., Structural biology of lipid modifying enzymes

Nurit, Ballas 1, Ph.D., 1989, Hebrew University, Israel: The cellular and molecular mechanisms underlying the initiation and rescue of Rett syndrome.

Chan, Chia-Hsin9Hsin4, Ph.D. 2007, National Taiwan University: Molecular mechanisms of cancer development; cancer metabolism and stemness.

Chen, Jiang8, M.D., Ph.D., 1995, Henan Medical University, China; 2001, University of Heidelberg, Germany: Planar cell polarity and primary cilia in skin and hair follicle development and skin cancers.

French, Jarrod1, Ph.D., Structural Biology, Chemical Biology and Enzymology of Metabolic Pathways and Protein complexes

Gao, Liang, Ph.D., 2009, Purdue University: Optical imaging, fluorescence microscopy, analytical instrumentation. Glynn, Steven 1 Ph.DGlynn, Steven1, Ph.D., Structure and mechanism of protein-unfolding machines in mitochondria

Kaczocha, Martin, Ph.D., 2009, Stony Brook University: Endocannabinoids, lipid metabolism, inflammation, and pain.

Kim, Hyungjin4, Ph.D., Genome instability, Ubiquitin/SUMO Signaling, Cancer pathogenesis - Regulation of DNA repair in cancer susceptibility pathways.

Kumar, Pawan 2, Ph.D., Immunology, gut microbiota-immune cells interaction. Intestinal and autoimmune inflammation.

Levy, Sasha F. 41, Ph.D., 2005, University of California, Santa Barbara: Physical and quantitative biology.

Luk, Ed2Ed1, Ph.D., 2003, John Hopkins University: Chromosome biology and genome regulation.

Martin, Benjamin L.21, Ph.D., 2005, University of California, Berkeley: Stem cell maintenance and differentiation; developmental mechanisms of cancer pathogenesis.

Matus, David Q.21, Ph.D., 2006, University of Hawaii: Evolutionary, cellular, and developmental approaches to studying nematode uterine-vulval morphogenesis.

Seeliger, JessicaJessica4, Ph.D., 2007, Stanford University: Chemical biology, biochemistry, microbiology. Mechanisms of lipid biosynthesis and transport in bacterial pathogens; developing tools for inducible gene .

Sheridan, Brian 2, Ph.D., Mucosal Immunology, T cell memory, Vaccine design, Host-pathogen interactions

Sneider, Ashly, Ph.D., Bioactive lipids and dietary fatty acids in inflammation and cancer.

Tan, Dongyan3, Ph.D., Structure and function of macromolecules involved in epigenetic regulation; biophysical behavior of model lipid membranes. Primary appointment: Department of Pharmacological Sciencesgene expression.

Adjunct Faculty

Dunn, John, Microbiologist.13 Ph.D., 1970, Rutgers University: Structure/function of bacteriophage T7 RNA polymerase.

Hannon, Gregory15 Ph.D., 1992, Case Western Reserve University: Genetics of growth in mammalian cells and dsRNA-induced gene silencing.

Joshua-Tor, Leemo15 Ph.D., 1991, The Weizmann Institute of Science: Structural biology;                           X-ray crystallography; molecular reconginition; nucleic acid regulation; RNAi.

Krainer, Adrian 15 Ph.D., 1986, Harvard University: mRNA splicing; gene expression; RNA-protein interaction. Lazebnik, Yuri, Professor.15 Ph.D., 1986, St. Petersburg State University, Russia: Molecular mechanisms of apoptosis.

Lowe, Scott, Professor.15 Ph.D. Massachusetts Institute of Technology: Modulation of apoptosis; chemosensitivity; senescence by cancer genes. Martienssen, Robert, Professor.15 Ph.D., Cambridge University: Plant genetics; transposons; development; gene regulation; DNA methylation.

Mills, Alea, A., Associate Professor.15 Ph.D., 1997 University of California: Cancer; development; aging; senescence; epigenetics.

Muthuswamy, Senthil, K., Assistant Professor15, Ph.D., 1995 McMaster University: Understanding cancer initiation using three-dimensional epithelial structures.

Setlow, Richard, Professor.1,13 Ph.D., 1947, Yale University: DNA damage and repair; carcinogenesis and mutagenesis in fish, light-induced malignant melanoma.

Spector, David L., Director of Research & Professor.15 Ph.D., 1980, Rutgers University: Spatial organization of gene expression.

Stenlund, Arne, Associate Professor.15 Ph.D., 1984, Uppsala University, Sweden: DNA replication of papillomaviruses.

Stillman, Bruce, President & Professor.15 Ph.D., 1979, Australian National University: DNA replication and chromatin assembly in human and yeast cells.

Studier, William, Professor.1,13 Ph.D., 1963, California Institute of Technoloy: Molecular genetics of phage T7: recombinant protein productions. Tansey, William P., Professor.15 Ph.D., 1991, University of Sydney, Australia: Regulation of oncoprotein stability.

Tonks, Nicholas, Professor.15 Ph.D., 1985, University of Dundee, Scotland: Characterization of protein tyrosine phosphatases.

Trotman, Lloyd C., Associate Professor, Ph.D., 2001, University of Zurich: Cancer modeling and treatment; senescence and tumor progression; cancer visualization; PTEN regulation.

Vakoc, Christopher, Assistant Professor.615 M.D., Ph.D., 2007, University of Pennsylvania: chromatin regulators and oncogenic signal transduction cascades.

Van Aelst, Linda, Associate Professor.15 Ph.D., 1991, University of Leuven, Belgium: Role of ras in mammalian cell transformation. Wigler, Michael, Professor.15 Ph.D., 1978, Columbia University: Genomics and cancer.

Wigler, Michael, Professor.15 Ph.D., 1978, Columbia University: Genomics and cancer.


Number of teaching, graduate, and research assistantships, fall 2011-12: 95

1)  Department of Biochemistry and Cell Biology

2)  Department of Molecular Genetics and Microbiology

3)  Department of Neurobiology and Behavior

4)  Department of Pharmacological Sciences

5)  Department of Pathology

6)  Department of Physiology and Biophysics

7)  Department of Psychiatry

8)  Department of Medicine

9)  Department of Chemistry

10)  Department of Oral Biology and Pathology

11)  Department of Obstetrics and Gynecology

12)  Department of Anatomical Sciences

13)  Brookhaven National Laboratory

14)  Recipient of the State University Chancellor’s Award for Excellence in Teaching, 1975

15)  Cold Spring Harbor Laboratory

16)  Department of Applied Math and Statistics

17)  Department of Neurosurgery



NOTE: The course descriptions for this program can be found in the corresponding program PDF or at COURSE SEARCH.