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Engineering Earlier Diagnosis of Heart Trouble An exciting partnership among researchers in Mechanical Engineering, Cardiothoracic Surgery and Biomedical Engineering has begun to develop new tools to detect regional changes in the heart up to three times more accurately than the current preferred technique. The researchers are applying computer-aided speckle interferometry, which permits whole field high spatial resolution measurement, to determine surface deformation and myocardial function, particularly the presence of regional ischemia, or an imbalance between oxygen demand and oxygen supply within the heart muscle, in the arrested and beating heart. Regional ischemia in the heart leads to regions of dysfunction, and the frequency of ischemic heart disease parallels and is at least as prevalent as coronary artery disease (CAD), the single most common cause of death in the United States, with a rate of almost 1 death per minute. The researchers, Fu-Pen Chiang, Chair of Mechanical Engineering; Irvin Krukenkamp, Chief of Cardiothoracic Surgery and co-director of University Hospital and Medical Center's Heart Hospital; and Glenn Gaudette, Evren Azeloglu, Lukasz Oleszak, and Adam Saltman, Biomedical Engineering, have published lead articles in Cardiovascular Engineering and the Annals of Biomedical Engineering describing their work, whose results had a spatial resolution three orders of magnitude higher than the current 'gold standard' technique. Profs. Chiang and Krukenkamp are receiving support from the National Science Foundation for this work, on which a paper was presented last week at the 25th annual meeting of the IEEE Engineering in Medicine and Biology Society. Since 'silent' ischemia is by definition difficult to detect, continued improvement of the new methodology could lead to earlier diagnosis. Prof. Chiang has published over 300 papers in 32 different journals and his research has been continuously funded for the last 34 years. He has been elected a Fellow of both the Optical Society of America and the Society for Experimental Mechanics, which also gave him its most prestigious prize, the Lazan Award, for "outstanding and original contributions to experimental mechanics" (optical metrology). |
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Stony Brook Home | VP for Research | Specialized Research Facilities | Centers for Molecular Medicine | GCRC | NSF MRSEC in Polymers at Engineered Interfaces | NSF MRSEC in Thermal Spray Research | NYS Center for Advanced Technology in Medical Biotechnology | NYS Center for Advanced Technology in Sensor Systems College of Arts and Sciences | College of Engineering and Applied Sciences | Graduate School | University Hospital and Medical Center | School of Medicine | Brookhaven National Laboratory |
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