BNL Van Survey

Thank you to all who responded to the BNL Van Service Survey. Your input is currently under consideration.

Essential Policy and Procedure Updates

New F&A (Indirect Cost) Rates

The Department of Health and Human Services (DHHS) has approved Facilities and Administrative Cost (Indirect Cost) rates for the University, for the next few years, covering the period 7/1/07-6/30/11. The revised rate structure is described below. Effective for all proposals due 11/12/07 and thereafter, these are the appropriate rates to use when submitting new proposals through The Research Foundation of SUNY. If the beginning of the budget period falls outside of the Research Foundation's fiscal year (7/1/-6/30), the F&A rate that is in effect at the onset of the budget period should be utilized, increasing annually in accordance with the rates below. Effective 7/1/08, the Office of Sponsored Programs will be incorporating the new rate structure into all funded proposals submitted prior to 11/12/07. This will affect the pace at which budgeted F&A costs are drawn down, but will not increase the amount of the Facilities and Administrative Costs charged against these awards nor affect Direct Cost budgets associated with these projects. These budgets are limited by the amounts approved at the time of the sponsored award.

Click Here to access the new F&A Rates.

Please note that the Office of Sponsored Programs will continue to honor special rates that are dictated by sponsor regulations and/or Stony Brook University/Research Foundation policies.  To view a copy of the current rate agreement please access the link at  http://www.stonybrook.edu/research/spo/IDCRateAgreement.pdf

Should you have any questions, please contact Ivar Strand, Assistant Vice-President of Sponsored Programs at 2-4402 or via e-mail at istrand@notes.cc.sunysb.edu.

Office of Sponsored Programs Has Made Changes to the 4 Page Form

The Office of Sponsored Programs has made some modifications to Section V, Proposed Research Activity Information on the Proposal/Award Processing Form (aka "4 page form"). These changes are needed to 1) ensure that the proper approvals are in place when faculty/staff are using the facilities of SB Southampton, 2) identify the use of Veterans Administration's patients, personnel or facilities and 3) alert the Department of Information Technology of any special IT needs.

Kindly utilize this revised form on all submissions effective 11/1/07. Please let me know if you have any questions. The form can be found at:
http://www.sunysb.edu/research/forms/ors/susb299.html

- Contributed by Ivar Strand, Assistant Vice President, Office of Sponsored Programs, Ivar.Strand@stonybrook.edu

November 2007 Update for CORIHS Investigators

Our Human Subject Protection Program (HSPP) has many active participants, including Principal Investigators and their study teams, staff of the Office of Research Compliance (ORC), and the membership of our Institutional Review Boards (IRBs). Our combined efforts continue to help ensure that our HSPP is solid and effective in keeping safe those individuals who volunteer to participate in our research activities at SBU.

The ORC and the IRBs are constantly evaluating the program to assess the need for clarifications of current SBU policies and procedures, promulgation of new policies and procedures, and dissemination of new federal guidance and regulations. The following is a summary of such actions that have been taken, including some clarifications of unchanged policies and procedures, since our last update in June 2007.

It is extremely important that you review this information with all members of your study team.

Research Compliance Reminder: Use of recombinant DNA and/or gene transfer technology requires prior Institutional Biosafety Committee Review/Approval!

You must apply to, and receive, approval (or confirmation of exemption) from SBU’s Institutional Biosafety Committee (IBC) prior to commencing with the following types of research:

Recombinant DNA research involves molecules that:
(a) are constructed outside living cells by joining natural or synthetic DNA segments to DNA molecules that can replicate in a living cell, or
(b) result from the replication of those described in (1).

Human gene transfer research involves the deliberate transfer of recombinant DNA, or DNA or RNA derived from recombinant DNA into the somatic cells of human subjects.

All the information you need regarding this requirement (including policies, procedures and applications) is provided here.

The federal Office of Biotechnology Activities (OBA), within the National Institutes of Health has jurisdiction over recombinant DNA and gene transfer activities conducted at SBU. Their guidelines and IBC requirements are applicable to all faculty, staff, students, and users of the facilities of this University who propose and conduct research involving recombinant DNA, regardless of source of funding. See IBC policy for approval requirements for activities conducted off-site at collaborating Institutions.

Recently, NIH issued a notice reminding the grantee community of the principles and requirements of the NIH Guidelines for Research Involving Recombinant DNA Molecules.
http://grants.nih.gov/grants/guide/notice-files/NOT-OD-07-096.html

Please review this notice for confirmation of the need for compliance in this area. If you have any questions, please contact Judy Matuk at Judy.Matuk@stonybrook.edu, or 632-9036.

NSF's New Proposal and Award Policies and Procedures Guide

The Guide consolidates two previous standalone NSF policy documents: the NSF Grant Proposal Guide (GPG) and the Grant Policy Manual (GPM) and combines them into a single electronic policy framework.   The Proposal & Award Policies & Procedures Guide will be effective for proposals submitted on or after June 1, 2007.  This document supersedes all prior versions of the GPG and GPM and can be accessed at: http://www.nsf.gov/publications/pub_summ.jsp?ods_key=nsf07140

The new guide increases ease of access to the policies and procedures that govern the entire grant lifecycle and eliminates duplicative and sometimes truncated coverage between the GPG and GPM.   

The Guide has two parts:

Part I - NSF's proposal preparation and submission guidelines – the NSF Grant Proposal Guide and the NSF Grants.gov Application Guide (to be incorporated at a later date).
Part II - Documents to guide, manage and monitor the administration of awards The Grant Policy Manual has been renamed the Award & Administration Guide (AAG).

Each Part contains a by-Chapter summary of significant changes to assist the user in navigating through the changes.   

The document is available as a fully Web-linked and searchable PDF version which gives users the ability to print either Parts of the Guide or the document in its entirety and in HTML. If you have any questions regarding the new NSF Proposal & Award Policies & Procedures Guide, please contact the Policy Office on 703-292-8243 or by e-mail to policy@nsf.gov.

NIH Non-Competing Grant Awards Under the Current Continuing Resolution

The Department of Health and Human Services (HHS) continues to operate on a continuing resolution (CR) that currently extends through November 16, 2007. The CR applies the terms of the FY 2007 appropriations for the period covered by the CR. Until the final FY 2008 appropriation is enacted, NIH will issue non-competing research grant awards at a level below that indicated on the most recent Notice of Award (generally up to 80% of the previously committed level). This is consistent with their past practice during the CRs of FY 2006 & 2007. NIH will consider upward adjustments to these levels after the final appropriation is enacted, but expects institutions to monitor their expenditures carefully during this period.

New Online Research Database

The Office of the Vice President for Research and Department of Information Technology are pleased to announce a new web-based database system that is available to all of the University community. The purpose of this system is to identify and record faculty research interests and expertise, and for delivery of available funding opportunities. Specifically, this shared resource is available to everyone at SBU, with easy navigation and one-stop access to the research interests, job history, publications and grants of all faculty and/or researchers. We are asking that every researcher on campus please complete or update their records. In the coming weeks and months, as the percentage of completed profiles increases, we expect that this database will be an extremely useful tool in identifying potential collaborators.

The second important feature of this system is the new Funding Opportunities web site. As our office collects funding opportunities each week from a variety of sources, we add them into the database, assigning to each a selection of disciplines and keywords. If the assigned keywords match those you've indicated in your profile, you will receive an automated weekly email providing you with the critical elements of the opportunity (sponsor, opportunity title, funding amounts, deadlines, synopsis, etc.) that you can click on and explore. Also, as a way of encouraging multidisciplinary collaboration, you'll see the names, email addresses and phone numbers of all other faculty who also matched the specific funding opportunity, and you'll be able to click on their profiles to learn more about them.

Links will take you to the database:
http://www.stonybrook.edu/researchinterests
http://www.stonybrook.edu/fundingopportunities.

To access it, you simply need your SBU NET ID and password (this can be found in SOLAR [click here for instructions]).

Please feel free to explore the features of this database. Remember, it is important that each faculty member and/or researcher complete his/her profile in order to fully benefit from this service.

Finally, we are very interested in visiting your department during a faculty meeting to demonstrate the database and show you some of its features. Please contact Stefanie Massucci at smassucci@notes.cc.sunysb.edu or 632-8589 to schedule a demo.

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Funding Opportunities

AACR Pancreatic Cancer Action Network Pilot Grants

Four Pilot Grants of $100,000 each will be awarded in 2008

Application Deadline: December 17, 2007
Grant Terms Begin: July 1, 2008

These grants are open to both Young Investigators (postdoctoral or clinical fellows; instructors; junior faculty; or the equivalent who are working under the auspices of a scientific mentor) with demonstrated potential for and commitment to pancreatic cancer research and Established Investigators.

Proposals will be accepted for innovative research projects that have a direct application or demonstrate relevance to the early detection or treatment of pancreatic cancer; projects may be in any discipline of basic, translational, clinical, or epidemiological cancer research. 
Proposals that will develop preliminary data necessary to prepare and submit a competitive research grant application to a major federal funding agency will also be accepted.

Special emphasis will be placed on research that is not duplicative of other efforts and has the potential for national application. 

Please visit the AACR Website or our application site proposalCENTRAL for additional details.

2007 Targeted Research Opportunity Awards

Committed funds for these awards totaled $1.13 million dollars in support of 16 highly meritorious projects selected from 60 applications from this and our affiliated institutions; 9 of the 16 newly-created FUSION awards were designed to develop interdisciplinary, cross-departmental translational research initiatives in anticipation of the University’s CTSA application.  This program accounted for 43 applications, attesting to the interactive nature of our biomedical research community and the awards encompassed faculty from 10 departments and 5 Schools/Colleges, fulfilling the highly collaborative spirit of this new award mechanism. 

This year's awardees:


Carol M. Baldwin Breast Cancer Research Awards

Paul R. Fisher, M.D.
Associate Professor, Department of Radiology
"3-D localization of breast lesions using breast tomosynthesis"

Michael Frohman, Ph.D.
Professor, Department of Pharmacological Sciences
"PLD2 therapeutic inhibitor for breast cancer metastasis"

Alexei Petrenko, Ph.D.
Senior Research Scientist, Department of Pathology
"Role of p63 in breast cancer"

Robert Rizzo, Ph.D.
Assistant Professor, Department of Applied Math & Statistics
"Structure-based design of ErbB family inhibitors"

Catacosinos Cancer Scholar Award

Srinivas Pentyala, Ph.D.
Associate Professor, Department of Anesthesiology
"Characterization and validation of prostate cancer markers"

Walk-For-Beauty Foundation Research Award

Christopher S. Lee, M.D.
Assistant Professor, Department of Urology
"Urinary cancer markers to predict prognosis and follow treatment"

Shinya Shibutani, Ph.D.
Senior Research Scientist, Department of Pharmacological Sciences
"Anti-breast cancer potential of soy isoflavones and their analogs"

FUSION Awards

David Brown, MD (PI)
Professor, Department of Medicine - Cardiovascular Medicine
Lisa Benz Scott, PhD (Co-PI)
Associate Professor, Department of Health Care Policy and Management
"African American Cardiac Patient Navigators to Improve Care Transitions"

Richard A. Clark, MD (PI)
Professor, Department of Biomedical Engineering
Adam J. Singer, MD (Co-PI)
Professor, Department of Emergency Medicine
"Fibronectin peptides for wound healing in diabetes"

Dmitri Gnatenko, PhD (PI)
Research Assistant Professor, Department of Medicine - Hematology
Wei Zhu, PhD (Co-PI)
Professor, Department of Applied Math & Statistics
"Class prediction model/tool to evaluate causes of Thrombocytosis"

Stefan Judex, PhD (PI)
Associate Professor, Department of Biomedical Engineering
Irwin Kurland, MD, PhD (Co-PI)
Professor, Department of Medicine
"A non-pharmacological prophylaxis for obesity"

James Konopka, PhD (PI)
Professor, Department of Molecular Genetics & Microbiology
Roger Johnson, PhD (Co-PI)
Professor, Department of Physiology & Biophysics
"Novel anti-fungal drug strategy"

Steffen Mueller PhD (PI)
Assistant Professor, Department of Molecular Genetics & Microbiology
Steven Skiena, PhD - (Co-PI)
Professor, Department of Computer Science
"Synthetic Viral Genome Design for Rapid Vaccine Development"

Iwao Ojima, PhD (PI)
Professor, Department of Chemistry, ICB & DD
Stanley Zucker, MD (Co-PI)
Professor, Department of Medicine, VAMC/Northpor
Maria Ryan, PhD (Co-PI)
Professor, Department of Oral Biology & Pathology
"Preclinical studies on DHA-SBT-1214 for IND filing"

Yingtian Pan, PhD (PI)
Associate Professor, Department of Biomedical Engineering
Wayne Waltzer, MD (Co-PI)
Professor, Department of Urology
Jingxuan Liu, MD (Co-PI)
Assistant Professor, Department of Pathology
"Optical biopsy for epithelial cancer diagnosis & grading"

Peter Tonge, PhD (PI)
Professor, Department of Chemistry
Thomas O'Riordan (Co-PI)
Associate Professor, Department of Medicine
"Aerosol delivery of TB drugs"

- http://www.osa.sunysb.edu/OsaHomepage/Programs/troAwards2007.html

Siemen’s Finalists Named

According to Newsday, ten of the fourteen Long Island high schoolers named regional finalists in the Siemen’s Competition in Math, Science and Technology were mentored by Stony Brook faculty. 

The national event, in its ninth year, carries college scholarship awards of up to $100,000.
Jim Whaley, president of the Siemens Foundation, said Long Island historically has been well represented, thanks to its combination of dedicated students and teachers and a supportive community.

A list of this year’s finalists and the complete article can be viewed here.
-- Newsday.com, November 13, 2007.

Upcoming Funding Opportunities

You can now access our new weekly Funding Opportunities Bulletin at http://www.stonybrook.edu/fundingopportunities. Here, you can search for Funding Opportunities by discipline, deadlines and keywords.

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News and Events

Announcements

Japan Society for the Promotion of Science

The JSPS Summer Program provides opportunities for young pre- and post-doctoral researchers from North America and Europe to receive an orientation on Japanese culture and research systems and to pursue research under the guidance of host researchers at Japanese universities and research institutions over a period of two months during the summer. For more information contact: http://www.nsf.gov/eapsi

New Genomics Server for Stony Brook Faculty

The Genomics Core Facility is pleased to announce the availability of a new genomics server for Stony Brook Faculty. The server can be accessed via the web and has the latest freezes for human, mouse and rat genomes, in the form of a mini-mirror of the Santa Cruz server. The site can be accessed at the following address: http://genomics01.arcan.stonybrook.edu/ For those wishing to perform large volume searches, please contact Jizu Zhi at jizu@osa.sunysb.edu or Eli Hatchwell at eli.hatchwell@stonybrook.edu.

Superbug web page

The Centers for Disease Control and Prevention (CDC) has posted a podcast on key facts about methicillin-resistant Staphylococcus aureus (MRSA) on a special web page dedicated to MRSA-related resources.

http://www.cdc.gov/ncidod/dhqp/ar_mrsa.html

Cancer Care needs to address general well-being

Cancer care that focuses solely on eradicating tumors without addressing the patient's general well-being falls short, says a new report from the Institute of Medicine. The report proposes that all oncology care providers routinely screen patients for distress and other problems; connect patients with psychosocial service providers and coordinate care with these professionals; and periodically re-evaluate patients to determine if any changes in care are needed.

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News

NPR Science Editor Reports on Novel Approach to Fat

NPR Science Editor Joe Palca reported on the air and in Science Times on findings by Professor and Chair, Clint Rubin, BME, that “standing on a gently vibrating platform for 15 minutes a day can build bone mass and reduce fat in mice.

The changes are due to a stem cell in bone marrow that can become muscle, bone or fat. Testing has begun in humans….fat and bone are cellular cousins — the same stem cell that's a precursor to bone cells is also a precursor to fat cells. Rubin said scientists have known for a good long while that bones that get a lot of shaking tend to get larger. Tennis players are a perfect example.

The theory for why vibrations affect bone mass is that somehow the bone-marrow stem cell senses the motion and begins turning itself into bone to better tolerate the jiggling. Rubin and his colleagues set up an experiment in which they gave two groups of mice identical diets, but one group was put on a gently vibrating platform for 15 minutes a day. When he measured the body fat of the group that got the daily jiggling, Rubin said, "Sure enough, they had 30 percent, 27 percent, less fat 15 weeks later."

The mice also had stronger bones, as Rubin reported in the Proceedings of the National Academy of Sciences. Scientists are about to launch a similar study in humans. Douglas Kiel works at the Institute for Aging Research at Hebrew Senior Life in Boston, where subjects will soon get 10 minutes of jiggling a day.

One important thing to note is that the vibrations do not remove fat cells. Rubin said that once fat cells form, they tend to stick around. And vibrating won't get rid of them. "If you have a fat mouse, in order to get rid of the fat, you need to metabolize it, just as we've all learned," Rubin said. "You need to get those mice out running marathons or pumping iron, or whatever it is that mice do to reduce their fat mass. Scientists are pretty clear that the techniques for reducing fat mass will work in humans, too.”

“Vibrations Shown to Build Bone, Reduce Fat.”  New York Times, 30 October, 2007, and
http://www.npr.org/templates/story/story.php?storyId=15721992&ft=1&f=1002

Stony Brook Student Wins Dr. Mow Shiah Lin Scholarship

Yuan Sun, a doctoral candidate in the Department of Materials Science and Engineering, has won the third annual Dr. Mow Shiah Lin Scholarship. The Asian Pacific American Association at Brookhaven National Laboratory initiated the scholarship, which consists of $1,000 and a plaque, to honor the distinguished late Brookhaven Lab scientist for which it is named. In honor of Lin's research, achievements and inventions, the scholarship is granted annually to an Asian immigrant with a student visa who is matriculating toward a graduate degree in environmental science, biology, or chemistry, in remembrance of the manner in which Lin began his career.

Yuan Sun earned a B.S. in chemistry and an M.S. in macromolecular science from Fudan University, Shanghai, in 1998 and 2001, consecutively. She earned another M.S. in materials science and engineering from Stony Brook University in 2005, and she expects to earn her Ph.D. in that field in December 2007.  Currently, Sun's research focuses on the synthesis of metallic nanomaterials and their applications in hydrogen storage and fuel cells. Her earlier research has already yielded practical results. She holds a patent from China for a method to prepare highly oil-absorbent resin, and she has filed for a U.S. patent for a method to synthesize platinum nanoparticles with applications in hydrogen storage and cancer treatment.

 

For More Information

Gail S. Habicht is Vice President for Research. She can be reached at (631) 632-7932. An abundance of specific information for the research community is available on our website, where past issues of this bulletin can also be found.

Office of the Vice President for Research -
http://www.stonybrook.edu/research/

Research News and Monday Memo archive - http://www.stonybrook.edu/research/monmemo/mmarchive.html

All Past issue of Research News and Monday Memo are keyword searchable. The index can be accessed at - http://www.stonybrook.edu/research/sitemap.html.

If you have information you would like to contribute to Research News please email it to the editor, Ann-Marie Scheidt, at amscheidt@notes.cc.sunysb.edu

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