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Daniel Klein, Ph.D.


State University of New York at Buffalo (1983)
Distinguished Professor, Clinical Psychology

Klein

Contact:

daniel.klein@stonybrook.edu
Office: Psychology B-444

Phone: (631) 632-7859

Lab Website

Temperament Study Website

Research Interests:

Dr. Klein is interested in developmental psychopathology and adult psychopathology, particularly mood disorders in children, adolescents, and adults. His research explores the intergenerational transmission of depression; the roles of temperament and emotional reactivity, and early adversity in the development and course of mood disorders; the long-term course and continuity of mood disorders; the classification of mood disorders; comorbidity between depression and other disorders; and the psychotherapeutic and psychopharmacological treatment of depressive disorders.

Current Research:

Dr. Klein is currently directing a longitudinal study of the role of early temperament and emotional style in the development of later mood and anxiety disorders in a large community sample of children. The children were assessed at ages 3, 6, and 9; assessments at age 12 and 15 are currently being planned. The study uses multiple measurement strategies to assess potential risk, protective, mediating, and moderating factors in multiple domains, including child emotional reactivity and regulation, executive functioning, psychopathology, psychophysiological and behavioral measures of biases in processing emotional information, susceptibility genes, stress and pubertal hormones, parenting, environmental and family stress, and parental personality and psychopathology. In addition, resting state and task-related functional magnetic resonance imaging (fMRI) measures are being collected on a subset of the larger sample 

Dr. Klein is also continuing to work with data sets from several past studies, including several multi-site clinical trials of the treatment of chronically depressed adults; a family and follow-up study of chronically depressed adult outpatients; and a family and follow-up study of a large community sample of adolescents. 

Dr. Klein is planning to take a student for Fall, 2016.

Recent Publications: 

In press

Beauchaine, T.P., & Klein, D.N. (in press). Developmental psychopathology and the Diagnostic and Statistical Manual of Mental Disorders. In T.P. Beauchaine and S.P. Hinshaw (Eds.), Child and adolescent psychopathology, 3rd ed. Hoboken, New Jersey: John Wiley & Sons. 

Dougherty, L. R., Smith, V. C., Bufferd, S. J., Kessel, E. M. Carlson, G. A., & Klein, D. N. (in press). Disruptive mood dysregulation disorder at age six and clinical and functional outcomes three years later. Psychological Medicine.

Goldstein, B.L., Shankman, S.A., Kujawa, A.J., & Klein, D.N. (in press). Developmental changes in electroencephalographic frontal asymmetry in young children at risk for depression. Journal of Child Psychology and Psychiatry.

Johnson, V. C., Olino, T. M., Klein, D. N., Dyson, M. W., Bufferd, S. J., Durbin, C. E., Dougherty, L.R., & Hayden, E. P. (in press). A longitudinal investigation of predictors of the stability of behavioural inhibition in early childhood. Journal of Research in Personality 

Kessel, E.M., & Klein, D.N. (in press). Depressivity and anhedonia. In V. Zeigler-Hill & D. K. Marcus (Eds.), The dark side of personality. Washington, DC: American Psychological Association.

Kessel, E.M., Meyer, A., Hajcak, G., Dougherty, L.R., Torpey-Newman, D.C., Carlson, G.A., & Klein, D.N. (in press). Transdiagnostic factors and pathways to multifinality: The error-related negativity distinguishes developmental trajectories from preschool persistent irritability to internalizing and externalizing symptoms at age 9. Development and Psychopathology

Klein, D.N., & Black, S. R. (in press). Persistent depressive disorder.  In R.J. DeRubeis & D.R. Strunk (Eds.), Oxford Handbook of Mood Disorders. New York: Oxford University Press. 

Klein, D.N., Goldstein, B.L., & Finsaas, M. (in press).  Depressive disorders.  In T.P. Beauchaine and S.P. Hinshaw (Eds.), Child and adolescent psychopathology, 3rd ed. Hoboken, New Jersey: John Wiley & Sons.  

Kopala-Sibley, D.C., Dougherty, L.R., Dyson, M.W., Laptook, R.S., Olino, T.M., Bufferd, S.J., & Klein, D.N. (in press). Early childhood cortisol reactivity moderates the effects of parenting on the development of children’s temperament in early childhood. Developmental Science.

Kopala-Sibley, D.C., & Klein, D.N. (in press). Depressive disorders: Presentation, classification, developmental trajectories, and course. In N. Cohen (Ed). Public Health Perspectives on Depressive Disorders. Baltimore: Johns Hopkins University Press.

Kopala-Sibley, D.C., & Klein, D.N. (in press). Distinguishing types of social withdrawal in children: Internalizing and externalizing outcomes of conflicted shyness versus social disinterest across childhood. Journal of Research in Personality

Kopala-Sibley, D.C., Danzig, A.P., Kotov, R., Bromet, E.J., Carlson, G.A., Olino, T.M., Bhatia, V., Black, S.R., & Klein, D.N. (in press). Negative emotionality and its facets moderate the effects of exposure to Hurricane Sandy on children's post-disaster depression and anxiety symptoms. Journal of Abnormal Psychology.

Kotelnikova, Y., Olino, T.M., Klein, D.N., Mackrell, S.V.M., & Hayden, E.P. (in press). Higher- and lower-order factor analyses of the Temperament in Middle Childhood Questionnaire. Assessment. 

Kujawa, A., Hajcak, G., Danzig, A.P., Black, S.R., Bromet, E.J., Carlson, G.A., Kotov, R., & Klein, D.N. (in press). Children’s neural reactivity to emotional stimuli prospectively predicts the impact of a natural disaster on psychiatric symptoms. Biological Psychiatry

Laws, H. B., Constantino, M. J., Sayer, A. G., Klein, D. N., Kocsis, J. H., Manber, R., Markowitz, J.C., Rothbaum, B. O., Steidtmann, D., Thase, M. E., & Arnow, B. A. (in press). Convergence in patient-therapist therapeutic alliance ratings and its relation to outcome in chronic depression treatment. Psychotherapy Research. 

Nelson, B. D., Perlman, G., Klein, D. N., Kotov, R., & Hajcak, G. (in press). Blunted neural response to rewards prospectively predicts the development of depression in adolescent girls. American Journal of Psychiatry

Parisette, A., Bufferd, S.J., & Klein, D.N. (in press). Parental predictors of children’s shame and guilt at age 6 in a multi-method, longitudinal study. Journal of Clinical Child and Adolescent Psychology

Shankman, S,A., Gorka, S.M., Katz, A.C., Klein, D.N., Markowitz, J.C., Arnow, B.A., Manber, R., Rothbaum, B.O., Thase, M.E., Schatzberg, A.F., Keller, M.B., Trivedi, M.H., & Kocsis, J.H. (in press). Side effects to antidepressant treatment in patients with depression and comorbid panic disorder. Journal of Clinical Psychiatry

Speed, B.C., Nelson, B.D., Auerbach, R.P., Klein, D.N., & Hajcak, G. (in press). Depression risk and electrocortical reactivity during self-referential emotional processing in 8-14 year old girls. Journal of Abnormal Psychology

2016

Allmann, A., Kopala-Sibley, D.C., Klein, D.N. (2016). Preschoolers’ psychopathology and temperament predict mothers’ later mood disorders. Journal of Abnormal Child Psychology, 44, 421-432.  

Carlson, G.A., Danzig, A.P., Dougherty, L.R., Bufferd, S.J., & Klein, D.N. (2016). Loss of temper and irritability: The relationship to tantrums in a community and clinical sample. Journal of Child and Adolescent Psychopharmacology, 26, 114-122. 

Huang, A., Klein, D.N., & Leung, H.-C. (2016). Load-related brain activity predicts spatial working memory performance in children aged 9-12. Developmental Cognitive Neuroscience, 17, 1-9. 

Kessel, E.M., Dougherty, L.R., Kujawa, A.J., Hajcak, G., Carlson, G.R., & Klein, D.N. (2016). Longitudinal associations between preschool Disruptive Mood Dysregulation Disorder symptoms and neural reactivity to monetary reward during preadolescence. Journal of Child and Adolescent Psychopharmacology, 26, 131-137. 

Klein, D.N., & Kotov, R. (2016). Persistence of depression in a 10-year prospective study: Evidence for a qualitatively distinct subtype. Journal of Abnormal Psychology, 125, 337-348. 

Kopala-Sibley, D.C., Kotov, R., Bromet, E.J., Carlson, G.A., Danzig, A.P., Black, S.R., & Klein, D.N. (2016). Personality diatheses and Hurricane Sandy: Effects on post-disaster depression. Psychological Medicine, 4, 865-875. 

Kotelnikova, Y., Olino, T.M., Klein, D.N., Kryski, K.R., & Hayden, E.P. (2016). Higher- and lower-order factor analyses of the Children’s Behavior Questionnaire in early and middle childhood. Psychological Assessment, 28, 92-108. 

Liu, K., Ruggero, C.J., Goldstein, B., Klein, D.N., Perlman, G., Broderick, J., & Kotov, R. (2016). Elevated cortisol in adolescent offspring of parents with posttraumatic stress disorder. Journal of Anxiety Disorders, 40, 37-43. 

Weinberg, A., Meyer, A., Hale-Rude, E., Perlman, G., Kotov, R., Klein, D.N., & Proudfit, G. (2016). Error-related negativity and sustained threat: Conceptual framework and empirical evaluation in an adolescent sample. Psychophysiology, 53, 372-385. 

2015

Brière, F.N., Rohde, P., Seeley, J.R., Klein, D.N., & Lewinsohn, P.M. (2015). Adolescent suicide attempts and adult adjustment.  Depression and Anxiety, 32, 270-276. 

Danzig, A.P., Dyson, M.W., Olino, T.M., Laptook, R.S., Klein, D.N. (2015). Child temperament moderates the association between parents’ positive affect expressed with the child and children’s subsequent social skills. Journal of Social and Clinical Psychology, 34, 411-435. 

Dougherty, L.R., Smith, V.C., Bufferd, S.J., Kessel, E., Carlson, G.A., & Klein, D.N. (2015). Preschool irritability predicts child psychopathology, functional impairment, and service use at age nine years.  Journal of Child Psychology and Psychiatry, 56, 999-1007. 

Dunlop, B.W., Hill, E., Johnson, B., Klein, D.N., Gelenberg, A.J., Rothbaum, B.O., Thase, M.E., & Kocsis, J.H. (2015). The effects of childhood sexual abuse on sexual functioning and relationship quality in chronically depressed adults. Journal of Sexual Medicine, 12, 813-823. 

Dyson, M.W., Olino, T.M., Durbin, C.E., Goldsmith, H.H., Bufferd, S.J., Miller, A.R., & Klein, D.N. (2015). The structural and rank-order stability of temperament in young children based on a laboratory-observational measure. Psychological Assessment, 27, 1388-1401. 

Goldstein, B.L., Hayden, E.P., & Klein, D.N. (2015). Stability of self-referent encoding task performance and associations with change in depressive symptoms from early to middle childhood. Cognition and Emotion, 29, 1445-1455. 

Gorka, S.M., Liu, H., Daughters, S.B., Klein, D.N., & Shankman, S.A. (2015). Is risk-taking propensity a familial vulnerability factor for alcohol use problems? An examination in two independent samples. Journal of Psychiatric Research, 68, 54-60. 

Kessel, E.M., Kujawa, A.J., Proudfit, G.H., & Klein, D.N. (2015). Neural sensitivity to reward differentiates social from generalized anxiety in children. Journal of Child Psychology and Psychiatry, 56, 792-800. 

Klein, D.N. (2015). Can course help reduce the heterogeneity of depressive disorders? In E. Bromet (Ed.), Long Term Outcomes in Psychopathology Research (pp. 32-52). New York: Oxford University Press. 

Klein, D.N., & Hajcak, G. (2015). Heterogeneity of depression:  Clinical considerations and psychophysiological measures. Psychological Inquiry, 26, 247-252. 

Kujawa, A.J., Glenn, C.R., Proudfit, G.H., & Klein, D.N. (2015). Affective modulation of the startle response among children at high and low risk for anxiety disorders. Psychological Medicine,45, 2647-2656. 

Kujawa, A.J., Proudfit, G.H., Laptook, R., & Klein, D.N. (2015).  Early parenting moderates the association between parental depression and neural reactivity to rewards and losses in offspring. Clinical Psychological Science, 3, 503-515. 

Meyer, A., Proudfit, G.H., Bufferd, S.J., Kujawa, A.J., Laptook, R.S., Torpey, D.C., & Klein, D.N. (2015). Self-reported and observed punitive parenting prospectively predicts increased error-related negativity in six-year-old children. Journal of Abnormal Child Psychology, 43, 821-829. 

Meyer, A., Proudfit, G.H., Torpey-Newman, D.C., Kujawa, A., & Klein D.N. (2015). Increased error-related brain activity in children predicts the onset of anxiety disorders three years later. Journal of Abnormal Psychology, 124, 266-274.

Nelson, B. D., Perlman, G., Hajcak, G., Klein, D. N., & Kotov, R. (2015). Familial risk for distress and fear disorders and emotional reactivity in adolescence: An event-related potential investigation. Psychological Medicine, 45, 2545–2556. 

Olino, T.M., & Klein, D.N. (2015). Self- and informant-reports of personality: Are the (psychometric) constructs the same? Assessment, 22, 655-664. 

Proudfit, G.H., Bress, J., Foti, D., Kujawa, A., & Klein, D.N. (2015). Depression and event related potentials: Emotional disengagement and reward insensitivity. Current Opinion in Psychology, 4, 110-113. 

Speed, B.C., Nelson, B.D., Perlman, G., Klein, D.N., Kotov, R., & Proudfit, G.H. (2015). Personality and emotional processing:  A relationship between extraversion and the late positive potential in adolescence. Psychophysiology, 52, 1039-1047.


2014

Olino, T.M., Dougherty, L.R., Bufferd, S.J., Carlson, G.A., & Klein, D.N. (2014). Testing models of psychopathology in preschool-aged children using a structured interview-based assessment. Journal of Abnormal Child Psychology, 42, 1201-1211. 
Kujawa, A.J., Proudfit, G.H., & Klein, D.N. (2014). Neural reactivity to reward in offspring of mothers and fathers with histories of depressive and anxiety disorders. Journal of Abnormal Psychology, 123, 287-297.
Kujawa, A.J., Dougherty, L.R., Durbin, C.E., Laptook, R.S., Torpey, D.C., & Klein, D.N. (2014). Emotion recognition in preschool 
children: Associations with maternal depression and early parenting.
Development and Psychopathology, 26, 159-170.
Klein, D.N., Bufferd, S.J., Ro, E., & Clark, L.A. (2014). Depression and comorbidity: Personality disorders. In C. S. Richards and M.W. O’Hara (Eds.) The Oxford Handbook of Depression and Comorbidity (pp. 200-217). New York: Oxford University Press.

Klein, D.N., Bufferd, S.J., Dyson, M.W., & Danzig, A.P. (2014). Personality pathology. In In M. Lewis and K.D. Rudolph (Eds.),
Handbook of Developmental Psychopathology, 3rd edition (pp. 703-719). New York: Springer.

Klein, D.N., & Allmann, A.E.S. (2014). Course of depression: Persistence and recurrence. In In I.H. Gotlib & C.L. Hammen (Eds.), Handbook of Depression and Its Treatment, 3rd edition (pp. 64-83). New York: Guilford Press.

Hill, R.M., Pettit, J.W., Lewinsohn, P.M., Seeley, J.R., & Klein, D.N. (2014). Escalation to Major Depressive Disorder among adolescents with subthreshold depressive symptoms: Evidence of multiple risk pathways. Journal of Affective Disorders, 158, 133-138.

Goldstein, B. & Klein, D.N. (2014). A review of selected candidate endophenotypes for depression.
Clinical Psychology Review, 34, 417-427.

Dougherty, L.R., Smith, V.C., Bufferd, S.J., Carlson, G.A., Stringaris, A., Leibenluft, E., & Klein, D.N.
(2014). DSM-5 Disruptive Mood Dysregulation Disorder: Correlates and predictors in young children. Psychological Medicine, 44, 2339–2350.
Carlson, G.A., & Klein, D.N. (2014). How to understand divergent views on bipolar disorder in youth. Annual Review ofClinical Psychology, 10, 529-551.
Bufferd, S. J., Dougherty, L. R., Olino, T. M., Dyson, M.W., Laptook, R. S., Carlson, G. A., & Klein, D. N. (2014). Predictors of the onset of depression diagnoses in young children: A multi-method, multi-informant longitudinal study from ages 3 to 6. Journal of Child Psychology and Psychiatry, 55, 1279-1287.
Brière, F.N., Rohde, P., Seeley, J.R., Klein, D., & Lewinsohn, P.M. (2014). Comorbidity between Major Depression and Alcohol Use Disorder from adolescence to adulthood. Comprehensive Psychiatry, 55, 526-533.


2013

Torpey, D.C., Hajcak, G., Kim, J., Kujawa, A.J., Dyson, M.W., Olino, T.M., & Klein, D.N. (2013).  Error-related brain activity in young children: Associations with parental anxiety and child temperamental negative emotionality. Journal of Child Psychology and Psychiatry, 54, 854-862.
Steidtmann, D., Manber, R., Blasey, C., Markowitz, J.C., Klein, D.N., Rothbaum, B.O., Thase, M.E., Kocsis, J.H., & Arnow, B.A. (2013). Detecting critical decision points in psychotherapy and psychotherapy + medication for chronic depression. Journal of Consulting and Clinical Psychology, 81, 783-792.
Stepp, S.D., Olino, T.M., Klein, D.N., Seeley, J.R., & Lewinsohn, P.M. (2013). Unique influences of adolescent antecedents on adult borderline personality disorder features. Personality Disorders: Theory, Research, Treatment, 4, 222-229. 
Sheikh, H.I., Kryski, K.R., Smith, H.J., Dougherty, L.R., Klein, D.N., Bufferd, S.J., Singh, S.M., & Hayden, E.P. (2013). Catechol-O-Methyltransferase gene val158met polymorphism and depressive symptoms during early childhood. American Journal of Medical Genetics Part B, B164, 245-252.
Shankman S.A., Campbell, M.L., Klein, D.N., Leon, A.C., Arnow, B.A., Manber, R., Keller, M.B., Markowitz, J.C., Rothbaum, B.O., Thase, M.E., & Kocsis, J.H. (2013). Dysfunctional attitudes as a moderator of pharmacotherapy and psychotherapy for chronic depression. Journal of Psychiatric Research, 47, 113-121.
Rohde, P., Lewinsohn, P.M., Klein, D.N., Seeley, J.R., & Gau, J.M. (2013). Key characteristics of major depressive disorder occurring in childhood, adolescence, emerging adulthood, and adulthood.  Clinical Psychological Science, 1, 41-53.
Pettit, J.W., Hartley, C., Lewinsohn, P.M., Seeley, J.R., & Klein, D.N. (2013). Is liability to recurrent major depressive disorder present before first episode onset in adolescence or acquired after the initial episode? Journal of Abnormal Psychology 122, 353-358.
Olino, T.M., Durbin, E.C., Klein, D.N., Hayden, E.P. & Dyson, M.W. (2013). Gender differences in young children’s temperament traits: An observational study. Journal of Personality, 81, 119-129.
Meyer, A., Hajcak, G., Torpey, D.C., Kujawa, A., Kim, J., Bufferd, S., Carlson, G., & Klein, D.N. (2013). Increased error-related brain activity in six-year- old children with clinical anxiety. Journal of Abnormal Child Psychology, 41, 1257-1266.
Kujawa. A.T., Weinberg, A., Hajcak, G., & Klein, D.N. (2013). Differentiating event-related potential components sensitive to emotion in middle childhood: Evidence from temporal-spatial PCA. Developmental Psychobiology, 55, 539-550. 
Kujawa, A.J., Klein, D.N., & Hajcak, G. (2013). Two-year stability of the late positive potential across middle childhood and adolescence. Biological Psychology, 94, 290-296.
Kryski, K.R., Dougherty, L.R., Sheikh, H.I., Dyson, M.W., Olino, T.M., Laptook, R.S., Singh, S.M., Klein, D.N., & Hayden, E.P. (2013). Effortful control and parenting: Associations with HPA axis reactivity in early childhood. Developmental Science, 16, 531-541.
Klein, D.N., Kujawa, A.J., Black, S.R., & Pennock, A.T. (2013).  Depressive disorders.  In T.P. Beauchaine and S.P. Hinshaw (Eds.), Child and adolescent psychopathology, 2nd ed. (pp. 543-576). Hoboken, New Jersey: John Wiley & Sons.  
Klein, D.K., Glenn, C.R., Kosty, D.B., Seeley, J.R., Rohde, P., Lewinsohn, P.M. (2013). Predictors of first lifetime onset of major depressive disorder in young adulthood. Journal of Abnormal Psychology, 122, 1-6.
Klein, D.N., & Black, S. R. (2013). Persistent depressive disorder: Dysthymia and chronic depression.  In W.E. Craighead, D.J. Miklowitz, and L.W. Craighead (Eds.), Psychopathology: History, theory, and diagnosis, 2nd ed. (pp. 334-363). Hoboken, N.J.: John Wiley & Sons. 
Hayden, E.P., Olino, T.M., Bufferd, S.J., Miller, A., Dougherty, L.R., Sheikh, H.I., Singh, S.M., & Klein, D.N. (2013). The serotonin transporter linked polymorphic region and brain-derived neurotrophic factor valine to methionine at position 66 polymorphisms and maternal history of depression: Associations with cognitive vulnerability to depression in childhood. Development and Psychopathology, 25, 587-598.
Hayden, E.P., Hanna, B., Sheikh, H.I., Laptook, R.S., Kim, J., Singh, S.M., & Klein, D.N. (2013). Child dopamine active transporter I genotype and parenting: Evidence for evocative gene-environment correlations. Development and Psychopathology, 25, 163-173.
Dougherty, L.R., Tolep, M.R., Bufferd, S.J., Olino, T.M., Dyson, M.W., Traditi, J., Rose, S., Carlson, G.A., & Klein, D.N. (2013). Preschool anxiety disorders: Comprehensive assessment of clinical, demographic, temperamental, familial, and life stress correlates. Journal of Clinical Child and Adolescent Psychology, 42, 577-589.
Dougherty, L.R., Smith, V., Olino, T.M., Dyson, M., Bufferd, S., Rose, S., & Klein, D.N. (2013).  Maternal depression and early child temperament predict young children’s salivary cortisol three years later. Journal of Abnormal Child Psychology, 41, 531-542.
Dougherty, L.R., Smith, V.C., Bufferd, S.J., Stringaris, A., Leibenluft, E., Carlson, G.A., & Klein, D.N.(2013). Preschool irritability: Associations with psychiatric disorders at age six and parental psychopathology. Journal of the American Academy of Child and Adolescent Psychiatry, 52, 1303-1313.
Danzig, A.P., Bufferd, S.J., Dougherty, L.R., Carlson, G.A., & Klein, D.N. (2013). Longitudinal associations between preschool psychopathology and school-age peer functioning. Child Psychiatry and Human Development, 44, 621-632.
Bress, J.N., Foti, D., Kotov, R., Klein, D.N., & Hajcak, G. (2013). Blunted neural response to rewards prospectively predicts depression in adolescent girls. Psychophysiology, 50, 74-81.
Beauchaine, T.P., Klein, D.N., Erickson, N.L., & Norris, A. (2013). Developmental psychopathology and the Diagnostic and Statistical Manual of Mental Disorders. In T.P. Beauchaine and S.P. Hinshaw (Eds.), Child and adolescent psychopathology, 2nd ed. (pp. 29-110). Hoboken, New Jersey: John Wiley & Sons.  
Arnow, B.A., Blasey, C., Steidtmann, D., Manber, R., Constantino, M.J., Klein, D.N., Markowitz, J.C., Rothbaum, B.O., Thase, M.E., & Kocsis, J.H. (2013). The relationship between the therapeutic alliance and treatment outcome in two distinct psychotherapies for chronic depression.  Journal of Consulting and Clinical Psychology, 81, 627-638.


2012

Weinberg, A., Klein, D.N., & Hajcak, G. (2012). Increased error-related brain activity distinguishes generalized anxiety disorder with and without comorbid major depressive disorder.Journal of Abnormal Psychology, 121, 885-896.
Torpey, D.C., Hajcak, G., Kim, J., Kujawa, A., & Klein, D.N. (2012). Electrocortical and behavioral measures of response monitoring in young children during a go/no-go task. Developmental Psychobiology, 54, 139-150.

Steidtmann, D., Manber, R., Arnow, B.A., Klein, D.N., Markowitz, J.C., Rothbaum, B.O., Vivian, D., Thase, M.E., & Kocsis, J.H. (2012). Patient treatment preference as a predictor of response and attrition in treatment for chronic depression.
Depression and Anxiety, 29, 896-905.

Smith, H.J., Sheikh, H.I., Dyson, M.W., Olino, T.M., Laptook, R.S., Hayden, E.P., Singh, S.M., & Klein, D.N. (2012). Parenting and child DRD4 genotype interact to predict children’s early emerging effortful control.
Child Development, 83, 1932-1944.
 
Olino, T.M., Yu, L., Klein, D.N., Rohde, P., Seeley, J.R., Pilkonis, P.A. & Lewinsohn, P.M.  (2012). Measuring depression using item response theory: An examination of three measures of depressive symptomatology. International Journal of Methods in Psychiatric Research, 21, 76-85.
 
Olino, T.M., Shankman, S.A., Klein, D.N., Seeley, J.R., Pettit, J.W., Farmer, R.F., & Lewinsohn, P.M. (2012). Lifetime rates of psychopathology in single versus multiple diagnostic assessments: Comparison in a community sample of probands and siblings. Journal of Psychiatric Research, 46, 1217-1222.
Olino, T.M., Klein, D.N., Farmer, R.F., Seeley, J.R., & Lewinsohn, P.M. (2012). Examination of the structure of psychopathology using latent class analysis. Comprehensive Psychiatry, 53, 323-332.
Meyer, A., Weinberg, A., Klein, D.N., & Hajcak, G. (2012).  The development of the error-related negativity (ERN) and its relationship with anxiety:  Evidence from 8 to 13 year-olds Developmental Cognitive Neuroscience, 2, 152-161.
Meyer, A., Klein, D.N., Torpey, D.C., Kujawa, A.J., Hayden, E.P., Sheikh, H.I., Singh, S.M., &  Hajcak, G. (2012). Additive effects of the dopamine D2 receptor (DRD2) and dopamine transporter (DAT1) genes on the error-related negativity (ERN) in young children. Genes, Brain, and Behavior, 11, 695-703.
 
May, A., Klonsky, E.D., & Klein, D.N. (2012). Predicting future suicide attempts among depressed suicide ideators: A 10-year longitudinal study. Journal of Psychiatric Research, 46, 946-952.
 
Kujawa, A.J., Klein, D.N., & Hajcak, G. (2012). Electrocortical reactivity to emotional images and faces in middle childhood to early adolescence. Developmental Cognitive Neuroscience, 2, 458-467.
 
Kujawa, A., Hajcak, G., Torpey, D., Kim, J., & Klein, D. N. (2012). Electrocortical reactivity to emotional faces in young children and associations with maternal and paternal depression. Journal of Child Psychology and Psychiatry, 53, 207-215.
 
Klein, D.N., Dyson, M.W., Kujawa, A.J., & Kotov, R. (2012). Temperament and internalizing disorders.  In M. Zentner and R. Shiner (Eds.), Handbook of Temperament (pp. 541-561). New York: Guilford Press.
 
Kim, J., Carlson, G.A., Meyer, S.E., Bufferd, S.J., Dougherty, L.R., Dyson, M.W., Laptook, R.S., Olino, T.M., & Klein, D.N. (2012). Correlates of the CBCL-Dysregulation Profile in preschool-aged children. Journal of Child Psychology and Psychiatry, 53, 918-926.
 
Glenn, C. R., Klein, D. N., Lissek, S., Britton, J. C., Pine, D. S., & Hajcak, G. (2012). The development of fear learning and generalization in 8 to 13 year-olds. Developmental Psychobiology, 54, 675-684. 
 
Foran, H.M., Vivian, D., O’Leary, K.D., Rothbaum, B.O., Keller, M.B., Kocsis, J.H., Nemeroff, C., Trivedi, M.H., & Klein, D.N. (2012) Risk for partner victimization and marital dissatisfaction among chronically depressed patients. Journal of Family Violence, 27, 75-85. 
 
Dyson, M.W., Olino. T.M., Durbin, C.E., Goldsmith, H.H., & Klein, D.N. (2012). The structure of temperament in preschoolers: A two-stage factor analytic approach. Emotion, 12, 44-57.
 
Constantino, M.J., Laws, H.B., Arnow, B.A., Klein, D.N., Rothbaum, B.O., Thase, M.E., & Manber, R., (2012). The relation between changes in patients’ interpersonal impact messages and outcome in treatment for chronic depression. Journal of Consulting and Clinical Psychology, 80, 354-364.
 
Bufferd, S.J., Dougherty, L.R., Carlson, G.A., Rose, S., & Klein, D.N. (2012). Psychiatric disorders in preschoolers: Continuity from ages 3 to 6. American Journal of Psychiatry, 169, 1157-1164.
 
Bress, J., Smith, E., Foti, D., Klein, D.N., & Hajcak, G. (2012). Neural response to reward and depressive symptoms from late childhood to early adolescence. Biological Psychology, 89, 156-162.
 
Black, S.R., & Klein, D.N. (2012). Early pubertal timing and risk for depressive symptoms in adolescent girls: The role of childhooddepression. Journal of Youth and Adolescence, 41, 1142-1150.


2011

 
Shankman, S.A., Sarapas, C., & Klein, D.N. (2011). The effect of pre vs. post-reward attainment on EEG asymmetry in melancholic depression. International Journal of Psychophysiology, 79, 287-295.
 
Shankman, S.A. Klein, D.N., Torpey, D.C., Olino, T.M., Dyson, M.W., Kim, J., Durbin, C.E., Nelson, B.D., & Tenke, C.E. (2011). Do positive and negative temperament traits interact in predicting risk for depression? A resting EEG study of 329 preschoolers. Development and Psychopathology, 23, 551-562.
 
Nelson. B.D., Shankman, S.A., Olino, T.M., & Klein, D.N. (2011). Defining reactivity: How several methodological decisions can affect conclusions about emotional reactivity in psychopathology. Cognition and Emotion, 25, 1439-1459.
 
McCullough, J.P., Jr., Lord, B.D., Martin, A.M., Conley, K.A., Schramm, E., & Klein, D.N. (2011). The Significant Other History: An interpersonal-emotional history procedure used with the early-onset chronically depressed patient. American Journal of Psychotherapy, 65, 225-248.
 
Kujawa, A.J., Torpey, D., Kim, J., Hajcak, G., Rose, S., Gotlib, I.H., & Klein, D.N. (2011). Attentional biases for emotional faces in young children of mothers with chronic or recurrent depression. Journal of Abnormal Child Psychology, 39, 125-135.
 
Klein, D.N., Leon, A.C., Li, C., D’Zurilla, T.J., Black, S.R., Vivian, D., Dowling, F., Arnow, B.A., Manber, R., Markowitz, J.C., & Kocsis, J.H. (2011). Social problem solving and depressive symptoms over time: A randomized clinical trial comparing Cognitive Behavioral Analysis System of Psychotherapy, Brief Supportive Psychotherapy, and pharmacotherapy. Journal of Consulting and Clinical Psychology, 79, 342-352.
 
Klein, D.N., Kotov, R., & Bufferd, S.J. (2011). Personality and depression: Explanatory models and review of the evidence. Annual Review of Clinical Psychology, 7, 269-295.
Kim, J., Klein, D.N., Olino, T.M., Dyson, M.W., Dougherty, L.R., & Durbin, E.C. (2011). Psychometric properties of the Behavioral Inhibition Questionnaire in preschool children. Journal of Personality Assessment, 93, 545-555.
Foti, D., Hajcak. G., Kotov, R., & Klein, D.N. (2011). Abnormal neural sensitivity to non-rewards versus rewards among adolescents at risk for depression. Journal of Abnormal Child Psychology, 39, 913-924.
Dyson, M.W., Olino, T.M., Dougherty, L.R., Durbin, C.E., & Klein, D.N. (2011).  Social and non-social behavioral inhibition in preschool-age children: Differential associations with parent-reports of temperament and anxiety. Child Psychiatry and Human Development, 42, 390-405.
Dougherty, L.R., Klein, D.N., Rose, S., & Laptook, R.S. (2011). Hypothalamic-pituitary-adrenal axis reactivity in the preschool-aged offspring of depressed parents: Moderation by early parenting. Psychological Science, 22, 650-658.
Dougherty, L.R., Bufferd, S.J., Carlson, G.A., Dyson, M.W., Olino, T.M., & Klein, D.N. (2011). Preschoolers’ observed temperament and DSM-IV psychiatric disorders assessed with a parent diagnostic interview. Journal of Clinical Child and Adolescent Psychology, 40, 295-306.
Bufferd, S.J., Dougherty, L.R., Carlson, G.A., & Klein, D.N. (2011).  Parent-reported DSM-IV disorders in a community sample of preschoolers. Comprehensive Psychiatry, 52, 359-369.
Angst, J., Gamma, A., Rössler, W., Ajdacic, V., & Klein, D.N. (2011). Childhood adversity and chronicity of mood disorders. European Archives of Psychiatry and Clinical Neuroscience, 261,21-27. 
 

Current Research Support:

National Institute of Mental Health (RO1 MH 069942), "Temperamental emotionality in preschoolers and depression risk." 
2004 - 2019. $6,789,330 (direct costs)
Principal Investigator

National Institute of Mental Health (RO1 MH 097767), “Trajectories of reward sensitivity and depression across adolescence”. 
2012-2017. $1,250,000 (direct costs).
Co-Investigator (PI: Greg Hajcak Proudfit)

National Institute of Mental Health (RO1 MH 093479) “Personality development and vulnerability to first-episode depression”. 
2012-2017. $1,789,347 (direct costs). 
Co-Investigator (PI: Roman Kotov)

National Institute of Mental Health (RO3 MH 094518), “Reward-related brain activity: 
Biomarker for risk of depression in childhood” 
2011-2013. $100,000 (direct costs). 
Co-Investigator (PI: Greg Hajcak)

National Institute of Mental Health (RO1 MH098093), “Family study of reward and threat sensitivity in internalizing psychopathology”
2012-2016 $1,970,349 (direct costs)
Co-Investigator (PI: Stewart Shankman)

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