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Daniel Klein, Ph.D.


State University of New York at Buffalo (1983)
Distinguished Professor, Clinical Psychology

Klein

Contact:

daniel.klein@stonybrook.edu
Office: Psychology B-444
Phone: (631) 632-7859

Lab Website

Temperament Study Website

Research Interests:

Dr. Klein is interested in developmental psychopathology and adult psychopathology, particularly mood disorders in children, adolescents, and adults. His research explores the intergenerational transmission of depression; the roles of temperament and emotional reactivity, and early adversity in the development and course of mood disorders; the long-term course and continuity of mood disorders; the classification of mood disorders; comorbidity between depression and other disorders; and the psychotherapeutic and psychopharmacological treatment of depressive disorders.

Current Research: 

Dr. Klein is currently directing a longitudinal study of the role of early temperament and emotional style in the development of later mood and anxiety disorders in a large community sample of children. The children were assessed at ages 3, 6, 9, and 12, and an assessment at age 15 is currently underway. The study uses multiple measurement strategies to assess potential risk, protective, mediating, and moderating factors in multiple domains, including child emotional reactivity and regulation, executive functioning, psychopathology, psychophysiological and behavioral measures of biases in processing emotional information, susceptibility genes, stress and pubertal hormones, parenting, environmental and family stress, and parental personality and psychopathology. In addition, resting state and task-related functional magnetic resonance imaging (fMRI) measures were collected on a subset of the larger sample. 

Dr. Klein is also continuing to work with data sets from several past studies, including several multi-site clinical trials of the treatment of chronically depressed adults; a family and follow-up study of chronically depressed adult outpatients; and a family and follow-up study of a large community sample of adolescents. 

Dr. Klein is planning to take a new student for Fall, 2018 pending approval of funding.

Recent Publications: 

In press

Barrios, C.S., Bufferd, S.J., Klein, D.N., & Dougherty, L.R. (in press). The interaction between parenting and children’s cortisol reactivity at age three predicts increases in children’s internalizing and externalizing symptoms at age six. Development and Psychopathology.

Bufferd, S.J., Dougherty, L.R., Olino, T.M., Dyson, M.W., Carlson, G.A., & Klein, D.N. (in press). Temperament distinguishes persistent from remitted anxiety disorders across early childhood. Journal of Clinical Child and Adolescent Psychology.

Craighead, W.E., Klein, D.N., Gillespie, C.F., Ritschel, L.A., & Phillips, K.E. (in press). Depressive disorders. In W.E. Craighead, D.J. Miklowitz, and L.W. Craighead (Eds.), Psychopathology: History, theory, and diagnosis, 3rd ed. Hoboken, N.J.: John Wiley & Sons.

Dougherty, L.R., Barrios, C.S., Carlson, G.A., & Klein, D.N. (in press). Predictors of later psychopathology in young children with disruptive mood dysregulation disorder (DMDD). Journal of Child and Adolescent Psychopharmacology.

Dougherty, L.R., Klein, D.N., & Olino, T.M. (in press). Depression in children and adolescents.  In J. Hunsley & E. Mash (Eds.), A guide to assessments that work 2nd ed. New York: Oxford University Press.

Ethridge, P., Kujawa, A., Dirks, M.A., Arfer, K.B., Kessel, E.M., Klein, D.N., & Weinberg, A. (in press). Neural responses to social and monetary reward in early adolescence and emerging adulthood. Psychophysiology.

Jin, J., Narayanan, A., Perlman, G., Luking, K., DeLorenzo, C., Hajcak, G., Klein, D.N., Kotov, R., & Mohanty, A. (in press). Orbitofrontal cortex activity and connectivity predict future depression symptoms in adolescence. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

Kann, S.J., O’Rawe, J.F., Huang, A.S., Klein, D.N., & Leung, H.-C. (in press). Preschool negative affect impacts activity and connectivity of the fusiform face area and amygdala in later childhood. Social, Cognitive, and Affective Neuroscience.

Kessel, E.M., Kujawa, A.J., Dougherty, L.R., Hajcak, G., Carlson, G.A., & Klein, D.N. (in press). Neurophysiological processing of emotion in children of mothers with a history of depression: The moderating role of preschool persistent irritability. Journal of Abnormal Child Psychology.

Kessel, E.M., Nelson, B.D., Kujawa, A., Hajcak, G., Bromet, E., Kotov, R., Carlson, G.A. & Klein, D.N. (in press). Hurricane Sandy-related stress exposure alters the development of neural reactivity to negative stimuli in children. Child Development. 

Klein, D.N., & Finsaas, M.C. (in press). The Stony Brook Temperament Study: Early antecedents and pathways to emotional disorders. Child Development Perspectives.

Klein, D.N., Finsaas, M.C., Goldstein, B.L., Kessel, E.M., Kopala-Sibley, D., & Kotov, R. (in press). Personality and depression. In V. Zeigler-Hill & T.K. Shackelford (Eds.), The SAGE Handbook of Personality and Individual Differences. Los Angeles: Sage.

Kopala-Sibley, D.C., Dougherty, L.R., Dyson, M.W., Laptook, R.S., Olino, T.M., Bufferd, S.J., & Klein, D.N. (in press). Early childhood cortisol reactivity moderates the effects of parenting on the development of children’s temperament in early childhood. Developmental Science.

Kopala-Sibley, D.C., Hayden, E.P., Singh, S.M., Sheikh, H.I., Kryski, K.R., & Klein, D.N. (in press). Gene-environment correlations in the cross-generational transmission of parenting: Grandparenting moderates the effect of child 5-HTTLPR genotype on mothers’ parenting. Social Development.

Kopala-Sibley, D.C., Jelinek, C., Allmann, A.E.S., & Klein, D.N. (in press). Parental depressive history, parenting styles, and child psychopathology over six years: The contribution of each parent’s depressive history to the other’s parenting styles. Development and Psychopathology.

Kopala-Sibley, D.C., & Klein, D.N. (in press). Depressive disorders: Presentation, classification, developmental trajectories, and course. In N. Cohen (Ed). Public Health Perspectives on Depressive Disorders. Baltimore: Johns Hopkins University Press.

Kopala-Sibley, D.C., Klein, D.N., Perlman, G., & Kotov, R. (in press). Self-criticism and dependency in female adolescents: Prediction of first onsets and disentangling the relationships between personality, life stress, and internalizing psychopathology. Journal of Abnormal Psychology.

Kotelnikova, Y., Olino, T.M., Klein, D.N., Mackrell, S.V.M., & Hayden, E.P. (in press). Higher- and lower-order factor analyses of the Temperament in Middle Childhood Questionnaire. Assessment.

Kujawa, J., Kessel, E., Carroll, A., Arfer, K., & Klein, D.N. (in press). Social processing in early adolescence: Associations between neurophysiological, self-report, and behavioral measures. Biological Psychology.

Laws, H. B., Constantino, M. J., Sayer, A. G., Klein, D. N., Kocsis, J. H., Manber, R., Markowitz, J.C., Rothbaum, B. O., Steidtmann, D., Thase, M. E., & Arnow, B. A. (in press). Convergence in patient-therapist therapeutic alliance ratings and its relation to outcome in chronic depression treatment. Psychotherapy Research.

Meyer, A., Hajcak, G., Hayden, E., Sheikh, H.I., Singh, S.M., & Klein, D.N. (in press). A genetic variant BDNF polymorphism interacts with hostile parenting to predict error-related brain activity in children and thereby risk for internalizing disorders. Development and Psychopathology.

Nelson, B.D., Infantolino, Z.P., Klein, D.N., Perlman, G., Kotov, R., & Hajcak, G.   (in press). Time-frequency activity to rewards provides incremental value in the prediction of adolescent-onset depression. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

Nelson, B.D., Kessel, E.M., Klein, D.N., & Shankman, SA. (in press). Depression symptom dimensions and asymmetrical cortical activity while anticipating reward. Psychophysiology.

Olino, T.M., Benini, L., Icenogle, G., Wilson, S., Klein, D.N., Seeley, J.R., & Lewinsohn, P.M. (in press). Is the assessment of personality comparable in persons who have and have not experienced depressive, anxiety, and substance use disorders? An examination of measurement invariance. Assessment.

Parisette, A., Bufferd, S.J., & Klein, D.N. (in press). Parental predictors of children’s shame and guilt at age 6 in a multi-method, longitudinal study. Journal of Clinical Child and Adolescent Psychology.

Qiu, T., Klonsky, E.D., & Klein, D.N. (in press). Hopelessness predicts suicidal ideation but not attempts: A 10-year longitudinal study. Suicide and Life Threatening Behavior.

Schuler, K. L., Ruggero, C. J., Goldstein, B., Perlman, G., Klein, D., & Kotov, R. (in press). Diurnal cortisol interacts with stressful events to prospectively predict depressive symptoms in adolescent girls. Journal of Adolescent Health

Schweizer, T., Olino, T.M., Dyson, M.W., Laptook, R.S., & Klein, D.N. (in press). Developmental origins of rumination in middle childhood: The roles of early temperament and positive parenting. Journal of Clinical Child and Adolescent Psychology

2017

Beauchaine, T.P., & Klein, D.N. (2017). Developmental psychopathology and the Diagnostic and Statistical Manual of Mental Disorders. In T.P. Beauchaine and S.P. Hinshaw (Eds.), Child and adolescent psychopathology, 3rd ed (pp. 33-67). Hoboken, New Jersey: John Wiley & Sons. 

Delaparte. L., Yeh, F.C., Adams, P., Malchow, A., Trivedi, M., Oquendo, M., Deckersbach, T., Ogden, T., Pizzagalli, D., Fava, M., Cooper, C., McInnis, M., Kurian, B., Weissman, M., McGrath, P., Klein, D., Parsey, R., & DeLorenzo, C. (2017). A comparison of structural connectivity in anxious depression versus non-anxious depression. Journal of Psychiatric Research, 89, 38-47.

Goldstein, B.L., Perlman, G., Kotov, R., Broderick, J.E., Liud, K., Ruggero, C., & Klein, D.N. (2017). Etiologic specificity of waking cortisol: Links with maternal history of depression and anxiety in adolescent girls. Journal of Affective Disorders, 208, 103-109.

Gromatsky, M., Waszczuk, M., Perlman, G., Salis, K., Klein, D. N., & Kotov, R. (2017). The role of parental psychopathology and personality in adolescent non-suicidal self-injury. Journal of Psychiatric Research, 85, 15-23.

Kessel, E.M., Allmann, A.E.S., Goldstein, B., Finsaas, M., Dougherty, L.R., Bufferd, S., Carlson, G.A., & Klein, D.N. (2017). Predictors, correlates, and outcomes of childhood primary enuresis. Journal of the American Academy of Child and Adolescent Psychiatry, 56, 250-257.

Kessel, E.M., Kujawa, A.G., Goldstein, B.L., Hajcak, G., Bufferd, S.J., Dyson, M.D., & Klein, D.N. (2017). Behavioral observations of positive and negative valence systems in early childhood predict physiological measures of emotional processing three years later. Journal of Affective Disorders, 216, 70-77.

Klein, D.N., & Black, S. R. (2017). Persistent depressive disorder.  In R.J. DeRubeis & D.R. Strunk (Eds.), Oxford Handbook of Mood Disorders (pp. 227-237). New York: Oxford University Press.

Klein, D.N., Goldstein, B.L., & Finsaas, M. (2017).  Depressive disorders.  In T.P. Beauchaine and S.P. Hinshaw (Eds.), Child and Adolescent Psychopathology, 3rd ed. (pp. 610-641). Hoboken, New Jersey: John Wiley & Sons. 

Kopala-Sibley, D.C., & Klein, D.N. (2017). Distinguishing types of social withdrawal in children: Internalizing and externalizing outcomes of conflicted shyness versus social disinterest across childhood. Journal of Research in Personality, 67, 27-35.

Le, T.M., Borghi, J.A., Kujawa, A.J., Klein, D.N., & Leung, H.-C. (2017). Alterations in visual cortical activation and connectivity with prefrontal cortex during working memory updating in major depressive disorder. Neuroimage Clinical, 14, 43-53.

Mackin, D. M., Perlman, G., Davila, J., Kotov, R., & Klein, D. N. (2017). Social support buffers the effect of interpersonal life stress on suicidal ideation and self-injury during adolescence. Psychological Medicine, 47, 1149-1161. 

Meyer, A., Danielson, C., Danzig, A.P., Bhatia, V., Black, S.R., Bromet, E., Carlson, G.A., Hajcak, G., Kotov, R., & Klein, D.N. (2017). Neural reactivity to mistakes and temperamental fearfulness prospectively predict the impact of Hurricane Sandy stressors on internalizing symptoms in children. Journal of the American Academy of Child and Adolescent Psychiatry, 56, 410–416.

Meyer, A., Hajcak, G., Glenn, C.R., Kujawa, A.J., & Klein, D.N. (2017). Error-related brain activity is related to aversive potentiation of the startle response in children. Emotion, 17, 487-496.

Shankman, S.A., Gorka, S.M., Katz, A.C., Klein, D.N., Markowitz, J.C., Arnow, B.A., Manber, R., Rothbaum, B.O., Thase, M.E., Schatzberg, A.F., Keller, M.B., Trivedi, M.H., & Kocsis, J.H. (2017). Side effects to antidepressant treatment in patients with depression and comorbid panic disorder. Journal of Clinical Psychiatry, 78, 433-440.

Stumper, A., Danzig, A.P., Dyson, M.W., Olino, T.M., Carlson, G.A., & Klein, D.N. (2017). Parents’ behavioral inhibition moderates association of preschoolers’ BI with risk for age 9 anxiety disorders. Journal of Affective Disorders, 210, 35-42.

2016

   Allmann, A., Kopala-Sibley, D.C., Klein, D.N. (2016). Preschoolers’ psychopathology and temperament predict mothers’ later mood disorders. Journal of Abnormal Child Psychology, 44, 421-432. 

Carlson, G.A., Danzig, A.P., Dougherty, L.R., Bufferd, S.J., & Klein, D.N. (2016). Loss of temper and irritability: The relationship to tantrums in a community and clinical sample. Journal of Child and Adolescent Psychopharmacology, 26, 114-122. 

Constantino, M. J., Laws, H. B., Coyne, A. E., Greenberg, R. P., Klein, D. N., Manber, R., ... & Arnow, B. A. (2016). Change in patients’ interpersonal impacts as a mediator of the alliance-outcome association in treatment for chronic depression. Journal of Consulting and Clinical Psychology, 84, 1135-1144. 

Dougherty, L. R., Smith, V. C., Bufferd, S. J., Kessel, E. M. Carlson, G. A., & Klein, D. N. (2016). Disruptive mood dysregulation disorder at the age of 6 years and clinical and functional outcomes 3 years later. Psychological Medicine, 46, 1103-1114. 

Furukawa, T.A., Schramm, E., Weitz, E.S., Salanti, G., Efthimiou, O., Michalak, J., Watanabe, N., Cipriani, A., Keller, M.B., Kocsis, J.H., Klein, D,N., & Cuijpers, P. (2016). Cognitive-Behavioral Analysis System of Psychotherapy (CBASP), drug or their combination: Differential therapeutics for persistent depressive disorder: A study protocol of an individual participant data network meta-analysis. BMJ Open, 6, e011769. 

Goldstein, B.L., Shankman, S.A., Kujawa, A.J., & Klein, D.N. (2016). Developmental changes in electroencephalographic frontal asymmetry in young children at risk for depression. Journal of Child Psychology and Psychiatry, 57, 1075-1082. 

Huang, A., Klein, D.N., & Leung, H.-C. (2016). Load-related brain activity predicts spatial working memory performance in children aged 9-12. Developmental Cognitive Neuroscience, 17, 1-9. 

Johnson, V. C., Olino, T. M., Klein, D. N., Dyson, M. W., Bufferd, S. J., Durbin, C. E., Dougherty, L.R., & Hayden, E. P. (2016). A longitudinal investigation of predictors of the stability of behavioural inhibition in early childhood. Journal of Research in Personality, 63, 51-61. 

Kessel, E.M., Dougherty, L.R., Kujawa, A.J., Hajcak, G., Carlson, G.R., & Klein, D.N. (2016). Longitudinal associations between preschool Disruptive Mood Dysregulation Disorder symptoms and neural reactivity to monetary reward during preadolescence. Journal of Child and Adolescent Psychopharmacology, 26, 131-137. 

Kessel, E.M., & Klein, D.N. (2016). Depressivity and anhedonia. In V. Zeigler-Hill & D. K. Marcus (Eds.), The dark side of personality (pp.307-324). Washington, DC: American Psychological Association. 

Kessel, E. M., Meyer, A., Hajcak, G., Dougherty, L. R., Torpey-Newman, D. C., Carlson, G. A., & Klein, D. N. (2016). Transdiagnostic factors and pathways to multifinality: The error-related negativity predicts whether preschool irritability is associated with internalizing versus externalizing symptoms at age 9. Development and Psychopathology, 28, 913-926. 

Klein, D.N., & Kotov, R. (2016). Persistence of depression in a 10-year prospective study: Evidence for a qualitatively distinct subtype. Journal of Abnormal Psychology, 125, 337-348. 

Kopala-Sibley, D.C., Danzig, A.P., Kotov, R., Bromet, E.J., Carlson, G.A., Olino, T.M., Bhatia, V., Black, S.R., & Klein, D.N. (2016). Negative emotionality and its facets moderate the effects of exposure to Hurricane Sandy on children's post-disaster depression and anxiety symptoms. Journal of Abnormal Psychology, 125, 471-481.

Kopala-Sibley, D.C., Kotov, R., Bromet, E.J., Carlson, G.A., Danzig, A.P., Black, S.R., & Klein, D.N. (2016). Personality diatheses and Hurricane Sandy: Effects on post-disaster depression. Psychological Medicine, 4, 865-875. 

Kotelnikova, Y., Olino, T.M., Klein, D.N., Kryski, K.R., & Hayden, E.P. (2016). Higher- and lower-order factor analyses of the Children’s Behavior Questionnaire in early and middle childhood. Psychological Assessment, 28, 92-108. 

Kujawa, A., Hajcak, G., Danzig, A.P., Black, S.R., Bromet, E.J., Carlson, G.A., Kotov, R., & Klein. D. N. (2016). Neural reactivity to emotional stimuli prospectively predicts the impact of a natural disaster on psychiatric symptoms in children. Biological Psychiatry, 80, 381–389. 

Liu, K., Ruggero, C.J., Goldstein, B., Klein, D.N., Perlman, G., Broderick, J., & Kotov, R. (2016). Elevated cortisol in adolescent offspring of parents with posttraumatic stress disorder. Journal of Anxiety Disorders, 40, 37-43. 

McCullough, Jr., J.P., Clark, S.W., Klein, D.N., & First, M.B. (2016). A procedure to graph the quality of psychosocial functioning affected by symptom severity. American Journal of Psychotherapy, 70, 222-231. 

McCullough, Jr., J.P., Clark, S.W., Klein, D.N., & First, M.B. (2016). Introducing a clinical course graphing scale for DSM-5 disorders. American Journal of Psychotherapy, 70, 383-392 

Nelson, B. D., Perlman, G., Klein, D. N., Kotov, R., & Hajcak, G. (2016). Blunted neural response to rewards as a prospective predictor of the development of depression in adolescent girls. American Journal of Psychiatry, 173, 1223-1230. 

Salis, K. L., Bernard, K., Black, S. R., Dougherty, L. R., & Klein, D. (2016). Examining the concurrent and longitudinal relationship between diurnal cortisol rhythms and conduct problems during childhood. Psychoneuroendocrinology, 71, 147-154. 

Speed, B.C., Nelson, B.D., Auerbach, R.P., Klein, D.N., & Hajcak, G. (2016). Depression risk and electrocortical reactivity during self-referential emotional processing in 8-14 year old girls. Journal of Abnormal Psychology, 125, 607-619. 

Weinberg, A., Meyer, A., Hale-Rude, E., Perlman, G., Kotov, R., Klein, D.N., & Proudfit, G. (2016). Error-related negativity and sustained threat: Conceptual framework and empirical evaluation in an adolescent sample. Psychophysiology, 53, 372-385.

2015

 Brière, F.N., Rohde, P., Seeley, J.R., Klein, D.N., & Lewinsohn, P.M. (2015). Adolescent suicide attempts and adult adjustment.  Depression and Anxiety, 32, 270-276.  

Danzig, A.P., Dyson, M.W., Olino, T.M., Laptook, R.S., Klein, D.N. (2015). Child temperament moderates the association between parents’ positive affect expressed with the child and children’s subsequent social skills. Journal of Social and Clinical Psychology, 34, 411-435.  

Dougherty, L.R., Smith, V.C., Bufferd, S.J., Kessel, E., Carlson, G.A., & Klein, D.N. (2015). Preschool irritability predicts child psychopathology, functional impairment, and service use at age nine years.  Journal of Child Psychology and Psychiatry, 56, 999-1007.  

Dunlop, B.W., Hill, E., Johnson, B., Klein, D.N., Gelenberg, A.J., Rothbaum, B.O., Thase, M.E., & Kocsis, J.H. (2015). The effects of childhood sexual abuse on sexual functioning and relationship quality in chronically depressed adults. Journal of Sexual Medicine, 12, 813-823.  

Dyson, M.W., Olino, T.M., Durbin, C.E., Goldsmith, H.H., Bufferd, S.J., Miller, A.R., & Klein, D.N. (2015). The structural and rank-order stability of temperament in young children based on a laboratory-observational measure. Psychological Assessment, 27, 1388-1401.  

Goldstein, B.L., Hayden, E.P., & Klein, D.N. (2015). Stability of self-referent encoding task performance and associations with change in depressive symptoms from early to middle childhood. Cognition and Emotion, 29, 1445-1455.  

Gorka, S.M., Liu, H., Daughters, S.B., Klein, D.N., & Shankman, S.A. (2015). Is risk-taking propensity a familial vulnerability factor for alcohol use problems? An examination in two independent samples. Journal of Psychiatric Research, 68, 54-60.  

Kessel, E.M., Kujawa, A.J., Proudfit, G.H., & Klein, D.N. (2015). Neural sensitivity to reward differentiates social from generalized anxiety in children. Journal of Child Psychology and Psychiatry, 56, 792-800.  

Klein, D.N. (2015). Can course help reduce the heterogeneity of depressive disorders? In E. Bromet (Ed.), Long Term Outcomes in Psychopathology Research (pp. 32-52). New York: Oxford University Press.  

Klein, D.N., & Hajcak, G. (2015). Heterogeneity of depression:  Clinical considerations and psychophysiological measures. Psychological Inquiry, 26, 247-252.  

Kujawa, A.J., Glenn, C.R., Proudfit, G.H., & Klein, D.N. (2015). Affective modulation of the startle response among children at high and low risk for anxiety disorders. Psychological Medicine, 45, 2647-2656.  

Kujawa, A.J., Proudfit, G.H., Laptook, R., & Klein, D.N. (2015).  Early parenting moderates the association between parental depression and neural reactivity to rewards and losses in offspring. Clinical Psychological Science, 3, 503-515.  

Meyer, A., Proudfit, G.H., Bufferd, S.J., Kujawa, A.J., Laptook, R.S., Torpey, D.C., & Klein, D.N. (2015). Self-reported and observed punitive parenting prospectively predicts increased error-related negativity in six-year-old children. Journal of Abnormal Child Psychology, 43, 821-829.  

Meyer, A., Proudfit, G.H., Torpey-Newman, D.C., Kujawa, A., & Klein D.N. (2015). Increased error-related brain activity in children predicts the onset of anxiety disorders three years later. Journal of Abnormal Psychology, 124, 266-274. 

Nelson, B. D., Perlman, G., Hajcak, G., Klein, D. N., & Kotov, R. (2015). Familial risk for distress and fear disorders and emotional reactivity in adolescence: An event-related potential investigation. Psychological Medicine, 45, 2545–2556. 

Olino, T.M., & Klein, D.N. (2015). Self- and informant-reports of personality: Are the (psychometric) constructs the same? Assessment, 22, 655-664.  

Proudfit, G.H., Bress, J., Foti, D., Kujawa, A., & Klein, D.N. (2015). Depression and event related potentials: Emotional disengagement and reward insensitivity. Current Opinion in Psychology, 4, 110-113.  

Speed, B.C., Nelson, B.D., Perlman, G., Klein, D.N., Kotov, R., & Proudfit, G.H. (2015). Personality and emotional processing:  A relationship between extraversion and the late positive potential in adolescence. Psychophysiology, 52, 1039-1047.


2014

 Olino, T.M., Dougherty, L.R., Bufferd, S.J., Carlson, G.A., & Klein, D.N. (2014). Testing models of psychopathology in preschool-aged children using a structured interview-based assessment. Journal of Abnormal Child Psychology, 42, 1201-1211. 

Kujawa, A.J., Proudfit, G.H., & Klein, D.N. (2014). Neural reactivity to reward in offspring of mothers and fathers with histories of depressive and anxiety disorders. Journal of Abnormal Psychology, 123, 287-297. 

Kujawa, A.J., Dougherty, L.R., Durbin, C.E., Laptook, R.S., Torpey, D.C., & Klein, D.N. (2014). Emotion recognition in preschool
children: Associations with maternal depression and early parenting. Development and Psychopathology, 26, 159-170. 

Klein, D.N., Bufferd, S.J., Ro, E., & Clark, L.A. (2014). Depression and comorbidity: Personality disorders. In C. S. Richards and M.W. O’Hara (Eds.) The Oxford Handbook of Depression and Comorbidity (pp. 200-217). New York: Oxford University Press.


Klein, D.N., Bufferd, S.J., Dyson, M.W., & Danzig, A.P. (2014). Personality pathology. In In M. Lewis and K.D. Rudolph (Eds.), Handbook of Developmental Psychopathology, 3rd edition (pp. 703-719). New York: Springer.

Klein, D.N., & Allmann, A.E.S. (2014). Course of depression: Persistence and recurrence. In In I.H. Gotlib & C.L. Hammen (Eds.), Handbook of Depression and Its Treatment, 3rd edition (pp. 64-83). New York: Guilford Press.

Hill, R.M., Pettit, J.W., Lewinsohn, P.M., Seeley, J.R., & Klein, D.N. (2014). Escalation to Major Depressive Disorder among adolescents with subthreshold depressive symptoms: Evidence of multiple risk pathways. Journal of Affective Disorders, 158, 133-138.

Goldstein, B. & Klein, D.N. (2014). A review of selected candidate endophenotypes for depression. Clinical Psychology Review, 34, 417-427.

Dougherty, L.R., Smith, V.C., Bufferd, S.J., Carlson, G.A., Stringaris, A., Leibenluft, E., & Klein, D.N.(2014). DSM-5 Disruptive Mood Dysregulation Disorder: Correlates and predictors in young children. Psychological Medicine, 44, 2339–2350. 

Carlson, G.A., & Klein, D.N. (2014). How to understand divergent views on bipolar disorder in youth. Annual Review ofClinical Psychology, 10, 529-551. 

Bufferd, S. J., Dougherty, L. R., Olino, T. M., Dyson, M.W., Laptook, R. S., Carlson, G. A., & Klein, D. N. (2014). Predictors of the onset of depression diagnoses in young children: A multi-method, multi-informant longitudinal study from ages 3 to 6. Journal of Child Psychology and Psychiatry, 55, 1279-1287. 

Brière, F.N., Rohde, P., Seeley, J.R., Klein, D., & Lewinsohn, P.M. (2014). Comorbidity between Major Depression and Alcohol Use Disorder from adolescence to adulthood. Comprehensive Psychiatry, 55, 526-533.


2013

 Torpey, D.C., Hajcak, G., Kim, J., Kujawa, A.J., Dyson, M.W., Olino, T.M., & Klein, D.N. (2013).  Error-related brain activity in young children: Associations with parental anxiety and child temperamental negative emotionality. Journal of Child Psychology and Psychiatry, 54, 854-862. 

Steidtmann, D., Manber, R., Blasey, C., Markowitz, J.C., Klein, D.N., Rothbaum, B.O., Thase, M.E., Kocsis, J.H., & Arnow, B.A. (2013). Detecting critical decision points in psychotherapy and psychotherapy + medication for chronic depression. Journal of Consulting and Clinical Psychology, 81, 783-792. 

Stepp, S.D., Olino, T.M., Klein, D.N., Seeley, J.R., & Lewinsohn, P.M. (2013). Unique influences of adolescent antecedents on adult borderline personality disorder features. Personality Disorders: Theory, Research, Treatment, 4, 222-229. 

Sheikh, H.I., Kryski, K.R., Smith, H.J., Dougherty, L.R., Klein, D.N., Bufferd, S.J., Singh, S.M., & Hayden, E.P. (2013). Catechol-O-Methyltransferase gene val158met polymorphism and depressive symptoms during early childhood. American Journal of Medical Genetics Part B, B164, 245-252. 

Shankman S.A., Campbell, M.L., Klein, D.N., Leon, A.C., Arnow, B.A., Manber, R., Keller, M.B., Markowitz, J.C., Rothbaum, B.O., Thase, M.E., & Kocsis, J.H. (2013). Dysfunctional attitudes as a moderator of pharmacotherapy and psychotherapy for chronic depression. Journal of Psychiatric Research, 47, 113-121. 

Rohde, P., Lewinsohn, P.M., Klein, D.N., Seeley, J.R., & Gau, J.M. (2013). Key characteristics of major depressive disorder occurring in childhood, adolescence, emerging adulthood, and adulthood.  Clinical Psychological Science, 1, 41-53. 

Pettit, J.W., Hartley, C., Lewinsohn, P.M., Seeley, J.R., & Klein, D.N. (2013). Is liability to recurrent major depressive disorder present before first episode onset in adolescence or acquired after the initial episode? Journal of Abnormal Psychology 122, 353-358. 

Olino, T.M., Durbin, E.C., Klein, D.N., Hayden, E.P. & Dyson, M.W. (2013). Gender differences in young children’s temperament traits: An observational study. Journal of Personality, 81, 119-129. 

Meyer, A., Hajcak, G., Torpey, D.C., Kujawa, A., Kim, J., Bufferd, S., Carlson, G., & Klein, D.N. (2013). Increased error-related brain activity in six-year- old children with clinical anxiety. Journal of Abnormal Child Psychology, 41, 1257-1266. 

Kujawa. A.T., Weinberg, A., Hajcak, G., & Klein, D.N. (2013). Differentiating event-related potential components sensitive to emotion in middle childhood: Evidence from temporal-spatial PCA. Developmental Psychobiology, 55, 539-550. 

Kujawa, A.J., Klein, D.N., & Hajcak, G. (2013). Two-year stability of the late positive potential across middle childhood and adolescence. Biological Psychology, 94, 290-296. 

Kryski, K.R., Dougherty, L.R., Sheikh, H.I., Dyson, M.W., Olino, T.M., Laptook, R.S., Singh, S.M., Klein, D.N., & Hayden, E.P. (2013). Effortful control and parenting: Associations with HPA axis reactivity in early childhood. Developmental Science, 16, 531-541. 

Klein, D.N., Kujawa, A.J., Black, S.R., & Pennock, A.T. (2013).  Depressive disorders.  In T.P. Beauchaine and S.P. Hinshaw (Eds.), Child and adolescent psychopathology, 2nd ed. (pp. 543-576). Hoboken, New Jersey: John Wiley & Sons.   

Klein, D.K., Glenn, C.R., Kosty, D.B., Seeley, J.R., Rohde, P., Lewinsohn, P.M. (2013). Predictors of first lifetime onset of major depressive disorder in young adulthood. Journal of Abnormal Psychology, 122, 1-6. 

Klein, D.N., & Black, S. R. (2013). Persistent depressive disorder: Dysthymia and chronic depression.  In W.E. Craighead, D.J. Miklowitz, and L.W. Craighead (Eds.), Psychopathology: History, theory, and diagnosis, 2nd ed. (pp. 334-363). Hoboken, N.J.: John Wiley & Sons. 

Hayden, E.P., Olino, T.M., Bufferd, S.J., Miller, A., Dougherty, L.R., Sheikh, H.I., Singh, S.M., & Klein, D.N. (2013). The serotonin transporter linked polymorphic region and brain-derived neurotrophic factor valine to methionine at position 66 polymorphisms and maternal history of depression: Associations with cognitive vulnerability to depression in childhood. Development and Psychopathology, 25, 587-598. 

Hayden, E.P., Hanna, B., Sheikh, H.I., Laptook, R.S., Kim, J., Singh, S.M., & Klein, D.N. (2013). Child dopamine active transporter I genotype and parenting: Evidence for evocative gene-environment correlations. Development and Psychopathology, 25, 163-173. 

Dougherty, L.R., Tolep, M.R., Bufferd, S.J., Olino, T.M., Dyson, M.W., Traditi, J., Rose, S., Carlson, G.A., & Klein, D.N. (2013). Preschool anxiety disorders: Comprehensive assessment of clinical, demographic, temperamental, familial, and life stress correlates. Journal of Clinical Child and Adolescent Psychology, 42, 577-589. 

Dougherty, L.R., Smith, V., Olino, T.M., Dyson, M., Bufferd, S., Rose, S., & Klein, D.N. (2013).  Maternal depression and early child temperament predict young children’s salivary cortisol three years later. Journal of Abnormal Child Psychology, 41, 531-542. 

Dougherty, L.R., Smith, V.C., Bufferd, S.J., Stringaris, A., Leibenluft, E., Carlson, G.A., & Klein, D.N.(2013). Preschool irritability: Associations with psychiatric disorders at age six and parental psychopathology. Journal of the American Academy of Child and Adolescent Psychiatry, 52, 1303-1313. 

Danzig, A.P., Bufferd, S.J., Dougherty, L.R., Carlson, G.A., & Klein, D.N. (2013). Longitudinal associations between preschool psychopathology and school-age peer functioning. Child Psychiatry and Human Development, 44, 621-632. 

Bress, J.N., Foti, D., Kotov, R., Klein, D.N., & Hajcak, G. (2013). Blunted neural response to rewards prospectively predicts depression in adolescent girls. Psychophysiology, 50, 74-81. 

Beauchaine, T.P., Klein, D.N., Erickson, N.L., & Norris, A. (2013). Developmental psychopathology and the Diagnostic and Statistical Manual of Mental Disorders. In T.P. Beauchaine and S.P. Hinshaw (Eds.), Child and adolescent psychopathology, 2nd ed. (pp. 29-110). Hoboken, New Jersey: John Wiley & Sons.   

Arnow, B.A., Blasey, C., Steidtmann, D., Manber, R., Constantino, M.J., Klein, D.N., Markowitz, J.C., Rothbaum, B.O., Thase, M.E., & Kocsis, J.H. (2013). The relationship between the therapeutic alliance and treatment outcome in two distinct psychotherapies for chronic depression.  Journal of Consulting and Clinical Psychology, 81, 627-638.

 

Current Research Support:

National Institute of Mental Health (RO1 MH 069942), "Temperamental emotionality in preschoolers and depression risk."

2004 - 2019. $6,789,330 (direct costs)

Principal Investigator (Co-Is: Gabrielle Carlson, Greg Hajcak, Joanne Davila, Thomas Olino) 

 

National Institute of Occupational Safety and Health (U02 OH011321), “Personality-informed care model for 9/11-related comorbid conditions.”

2016-2021. $2,283,267 (direct costs)

Co-Investigator (PI: Roman Kotov) 

 

National Institute of Mental Health (R21 MH108766) “Targeting biomarkers of risk for depression and anxiety through a parenting intervention”

2016-2018.  $275,000 (direct costs).

Co-Investigator (PIs: Kristin Bernard and Greg Hajcak). 

 

National Institute of Mental Health (RO1 MH 097767), “Trajectories of reward sensitivity and depression across adolescence”.

2012-2017. $1,250,000 (direct costs).

Co-Investigator (PI: Greg Hajcak) 

 

National Institute of Mental Health (RO1 MH 093479) “Personality development and vulnerability to first-episode depression”.

2012-2017. $1,789,347 (direct costs).

Co-Investigator (PI: Roman Kotov)

 

Primary Mentor on Graduate Fellowship Awards:

National Institute of Mental Health Predoctoral National Research Service Award to Ellen M. Kessel

National Science Foundation Graduate Research Fellowship to Megan Finsaas

 

 

 

 

 

 

 

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