Welcome to the Ojima Research Group Website
 
 
Group News and Announcements

 
Congratulations to Bora Park for receiving her PhD. degree! We wish her good luck at UC-Berkeley!
 
Congratulations to Yao Zong, Yaozhong Zhang, and Su Yan for passing their first meetings and became PhD. candidates!
 
Congratulations to Yang Zang for receiving his PhD. degree! We wish him good luck at Wuxi AppTech in Wuhan, China!
 
Congratulations to Jacob Vineberg for receiving his PhD. degree and the award of Excellence in Doctoral Research! We wish him good luck at Pfizer!
 
Congratulations to Divya Awasthi for receiving her PhD. degree and the Maria Tzamarioudaki Memorial Award for Outstanding Doctoral Student! We wish her good luck at Rutgers University in New Brunswick!
 

 
Synthetic Organic and Medicinal Chemistry at the Biomedical Interface

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Discovery and development of new and potent anticancer agents, antibacterial agents, anti-inflammatory agents, and various enzyme inhibitors are the major research interests in Professor Ojima's laboratory. Integration of all relevant chemistry and biological tools, including computational biology (docking, in silico screening, molecular dynamics), chemical biology (protein expression, enzyme assays, fluorescence labeling), cell biology (cell culture, cytotoxicity assay, fluorescent confocal microscopy, flow cytometry, transmission and scanning electron microscopy), has successfully been realized in this program. Naturally, this research program is promoted in close collaboration with cell biologists, oncologists, microbiologist, pharmacologists, hematologists, toxicologists, etc., as well as the  Division of Laboratory Animals Resources for in vivo efficacy evaluations. The Ojima Laboratory has also been exploring and developing new synthetic methodologies, especially based on catalytic organic transformations, including enantioselective processes, cyclohydrocarbonylations and higher order cycloadditions and carbocyclizations, which provide the basis for the efficient syntheses of biologically active substances of medicinal interest, such as those anticancer and antibacterial agents mentioned above.


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The Ojima Research Laboratory 2014



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Department of Chemistry, Stony Brook University, Stony Brook, New York 11794-3400 Phone: (631) 632-7890
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