Dr. Arthur P. Grollman is Distinguished Professor of Pharmacological Sciences, Evelyn G. Glick Professor of Experimental Medicine, and Director of the Zickler Laboratory of Chemical Biology at Stony Brook University. In 1974, he was appointed (founding) Chairman of the Department of Pharmacological Sciences at Stony Brook. Under his leadership, Pharmacological Sciences ranked consistently among the top Departments of Pharmacology in the United States. In 2000, he relinquished his administrative responsibilities to devote full time to research.
Dr. Grollman has published more than 200 papers in the fields of molecular biology and cancer research. His current research interests focus on the biological consequences of DNA damage as they relate to molecular mechanisms of DNA replication, mutagenesis, and DNA repair. Research in the Grollman laboratory was instrumental in establishing the mechanism of action of the antitumor agent bleomycin and in defining the biochemical pathway that protects cells against mutations produced by oxidative DNA damage. Recently, he and his colleagues established the three-dimensional structures of DNA glycosylases and DNA polymerases bound to site-specifically modified DNA, thereby correlating molecular structure of damaged DNA with biologic function. Currently, he directs a research program focusing on the environmental and genetic causes of endemic nephropathy and its associated urothelial cancer.
Dr Grollman is a recognized expert on the clinical pharmacology of herbal medicines and testified on this subject before the White House Commission on Alternative and Complementary Health Policy, the Senate Subcommittee on Commerce, Science and Transportation (Sen. John McCain, Chair) and Governor George Pataki’s Task Force on Life and Law.
Dr. Grollman received his B.A. in Chemistry from the University of California at Berkeley and his M.D. from the Johns Hopkins School of Medicine. Following internship and residency in Internal Medicine at Johns Hopkins, he conducted research at the National Institutes of Health. He then joined the faculty of the Albert Einstein College of Medicine, Bronx, N.Y., where he became Professor of Medicine, Pharmacology and Molecular Biology. He served concurrently as Associate Dean for Scientific Affairs at Albert Einstein from 1970 to 1972 and held a similar position in the School of Medicine at Stony Brook University from 1994 to 1996.
Dr. Grollman served as Attending Physician in Medicine at hospitals associated with the Albert Einstein College of Medicine and with the Stony Brook University School of Medicine. He has held Visiting Professorships at Stanford University, Johns Hopkins School of Medicine, University of California at San Francisco, the National Cancer Research Center (Japan), and the Weizmann Institute (Israel).
Dr. Grollman has served on numerous scientific advisory committees and editorial boards and is currently a member of the Board of Scientific Counselors of the National Institute of Environmental Health Sciences. He has received an American Cancer Society Scholarship Award, a MERIT award from the National Cancer Institute and was recently elected to the Johns Hopkins Society of Scholars.