PhD candidate in the Department of Molecular & Cellular Pharmacology
'Understanding the Role of Cholesterol Utilization in Mycobacterium tuberculosis'
Synopsis: Tuberculosis is a major world health problem, recently becoming the leading cause of death due to an infectious agent. The global effort to eradicate this disease has been dampened by increases in multi-drug resistant strains. Thus, the need for new therapeutics is imperative. During infection, cholesterol is a major nutrient and influences bacterial survival and pathogenicity. My research aims to characterize enzymes within the cholesterol catabolic pathway and investigate how the bacteria regulates its metabolism. Acquiring a better understanding of how M. tuberculosis utilizes cholesterol will help identify biological targets vulnerable to therapeutic intervention.
Biography: Amber Bonds is a New York native, growing up in Westchester County. She attended the University of New Haven in West Haven, CT; earning bachelors degrees in Forensic Science and Biochemistry. While in college, Amber was active in several on-campus organizations and a mentor in the Women of Power Network. She conducted research as REU summer student at the University of Oregon. Under the mentorship of Dr. Diane Hawley, Amber investigated the interactions between RNA Polymerase II and transcription factors in Saccharomyces cerevisiae. Her research interests include pathogen-host interactions and the development of new therapeutics for treating infectious diseases. Amber’s dissertation research investigates the role of cholesterol utilization in Mycobacterium tuberculosis with the aim to identify new therapeutic targets. She is a Turner Fellow in the Center for Inclusive Education. Apart from research, Amber is an avid sports fan and enjoys yoga, Zumba and traveling (with plans to visit all seven continents).
Thursday, february 15, 2018 at 12:30 PM