Molecular Genetics and Microbiology - Research Sponsors

FALL 2012 SEMESTER


Departmental Sponsors   Course   Sect.   Research Interests

Benach, Jorge   BIO 487   T69   Pathogenesis of spirochetal infections and host responses

Bhaduri-McIntosh, Sumita           Understand Epstein-Barr virus (EBV)-host relationships and the pathogenesis of EBV-mediated disease.  Dissecting the early cellular events critical for susceptibility of B cells to EBV-driven proliferation. Reveal the determinants of resistance or susceptibility of latently-infected B cells to stimuli that trigger a switch from EBV latency to lytic cycle.  Delineating EBV-directed immune responses during health and disease. 

Bliska, James   BIO 487   T98   Molecular and cellular basis of bacterial-host cell interactions; bacterial pathogenesis  

Carpino, Nicholas           Understanding how the immune system protects us from various diseases. Specifically, how the Sts proteins and other key molecules regulate T cell activation. 

Carter, Carol           Role of cellular proteins in retroviral protein assembly. Structure and dynamics of retroviral proteins. Identification of determinants of capsid protein assembly and disassembly. Gag precursor assembly on model membrane systems. Regulation of PR activity in its precursor form. Molecular basis of resistance to drugs that target PR.

Chan, Edward           Investigating the role of cell surface tyrosine kinase receptors as cancer biomarkers and therapeutic targets. Investigation into the mechanisms by which tyrosine kinase receptors affect tumor growth, malignant transformation and cancer cells response to chemotherapy. Translating the findings of these mechanistic studies to personalized target therapy for patients with cancers. Our long term goal is to provide a platform for rapid translation of basic science discoveries to innovative cancer clinical trials. 

             

Delihas, Nicholas   BIO 487   T46    Regulation of gene expression by small RNAs. Annotation of genes. Repetitive sequences in intergenic regions in bacteria

Del Poeta, Maurizio           Sphingolipid metabolism and signaling in fungal and mammalian cells to identify new markers for early diagnosis and specific microbial enzymes/molecules essential to cause infection in the attempt to develop new antifungal targets.

Furie, Martha   BIO 487   T75    Molecular mechanisms controlling the movement of leukocytes across the vessel wall, particularly in the context of bacterial infections. two bacterial illnesses, Lyme disease and tularemia 

Futcher, Bruce           Understanding the basic mechanism that controls cell division 

Hayman, Michael   BIO 487   T81   Signal transduction in cell growth, differentiation and cancer; nuclear and membrane oncoproteins

Hearing, Janet           Development of Antiviral Drugs to Combat Influenza. Replication and maintenance of the Epstein-Barr virus genome in latently infected cells

Hearing, Patrick   BIO 487   T25   Adenovirus-host cell interactions; viral vectors for human gene therapy

Karzai, Wali   BIO 487   T50   Structure and function of RNA-binding proteins and biochemical studies of the SmpB•tmRNA quality control system 

Konopka, James   BIO 487   T86   Signal transduction, morphogenesis and genetics of pathogenic fungi

Krug, Laurie   BIO 487   T02   Virus-host infections during chronic gammaherpesvirus infection

Leatherwood, Janet           Cell Cycle Transcription Circuits. Regulation of DNA Replication Control. Regulation of Gene Expression in the Meiotic Cell Cycle

Li, Ellen           Gastroenterology and Hepatology

Mackow, Erich           Role of hantavirus β3 interactions in regulating endothelial cell permeability, platelet recruitment and the role of altered receptor functions as a mechanism of hantavirus pathogenesis

Marcu, Kenneth   BIO 487   T24   Structure and function of RNA-binding proteins and biochemical studies of the SmpB•tmRNA quality control system 

Paul, Aniko           Viral replication and genetics at the cellular level, and mechanisms of viral pathogenensis in a host organism 

Reich Marshall, Nancy C.   BIO 487   T36   Signaling switches in gene expression by hormones or viral infection  

Spitzer, Eric   BIO 487   T96   Molecular biology of microbial pathogens  

Steigbigel, Roy   BIO 487   T97   Mononuclear and polymorphonuclear phagocyte functions; macrophage function in human immunodeficiency virus (HIV) infection  

Thanassi, David   BIO 487   T44   Secretion of virulence factors by bacterial pathogens; pilus biogenesis by uropathogenic Escherichia coli

van der Velden, Adrianus    BIO 487   T27    Mammalian T cell response to Salmonella enterica serovar Typhimurium

Wimmer, Eckard    BIO 487   T45    Molecular biology of poliovirus replication; picornaviral pathogenesis

Zong, Wei-Xing   BIO 487   T76    Study the molecular regulation of cancer cell death despite their impaired apoptosis machinery

Undergraduate Biology, 107-112 CMM/BLL, Stony Brook University, Stony Brook, NY 11794-5110 - 631 632-8530, 631-632-1680 (fax)