Chemistry (Chemical Biology) Research Sponsors

SPRING 2012
Faculty Sponsor   Course   Sect.   Crs #   Research Interests
Boon, Elizabeth               Fundamentals and applications in biological sensing. Prokaryotic nitric oxide biology. Fundamentals and applications of the H-NOX family. Peptide and protein engineering for novel sensing applications.
Carrico, Isaac               Introduction of small molecules into biological systems for the purpose of tracking or perturbing cellular processes. Metabolic engineering. Protein engineering. Bioorthogonal reaction development.
Druekhammer, Dale               Computer-based design and synthesis of receptors and sensors for biomolecules. Design and synthesis of enzyme inhibitors. Enzyme reaction mechanisms
Ojima, Iwao               Design, synthesis, and structure-activity relationships of medicinally-active compounds, especially for the drug design and discovery of anticancer agents and antimicrobials. Development of new and efficient methods for the synthesis of biologically active compounds of medicinal interests.
Raleigh, Dan               Experimental studies of protein folding and amyloid formation.
Rudick, Jon               Design and synthesis of bioactive oligomers, peptides and bioconjugates. Molecular recognition of biomacromolecules. Nanostructured materials for biotechnology applications (e.g., sensors and diagnostics).
Sampson, Nicole   BIO 487   T94   42716   Bioorganic chemistry and mechanistic enzymology. Investigation of the structure and function of cholesterol oxidase protein-membrane interactions, and its relationship to Mycobacterium tuberculosis pathogenesis. Synthesis of peptides and polymers to probe the role of ADAM proteins in mammalian fertilization.
Simmerling, Carlos   BIO 487   T04    41730    Development of tools for efficient simulation of chemical systems and using them to study the structure and dynamics of molecules involved in biological processes.
Tonge, Peter   BIO 487   T64   42693   Biological chemistry and enzymology. Quantitating substrate strain in enzyme-catalyzed reactions using vibrational and NMR spectroscopies. Rational drug design. Pathogenesis of Mycobacterium tuberculosis. Structure-function studies of fluorescent proteins.
Wang, Jin               Theoretical biophysics and biophysical chemistry; protein folding; molecular recognition; biomolecular reaction dynamics; single molecules.

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