Faculty

Name

Department

Areas of Interest

     
Allaire, Mark Brookhaven National Lab application of synchrotron-based techniques for chemical genetics and to study the structure and function of proteins
     
Boon, Elizabeth Chemistry Nitric oxide signaling in bacteria.
     
Bowen, Mark Physiology & Biophysics Single molecule spectroscopy; Coordination of post-synaptic glutamate receptor signaling by the MAGUK family of scaffolds
     
Brown, Deborah Biochemistry The Brown lab studies caveolin-1 and other caveolar proteins, to understand how their interactions with each other and with the membrane and cytoskeleton are important in function in normal and cancer cells.
     
Czaplinski, Kevin Biochemistry Post-transcriptional control of gene expression in the nervous system
     
de los Santos, Carlos Pharmacology Research in our laboratory focuses on the determination of the solution structure DNA molecules damaged by endogenous and exogenous agents, and to establish structure-function relationships relating to mutagenesis and DNA repair.
     
Carrico, Isaac Chemistry The research in our group centers around the concept of chemical biology. In paticular, we introduce unnatural monomers into the biopolymers of life (proteins, oligosaccharides, oligonucleotides) for the purpose of tracking or perturbing biological processes.
     
Deutsch, Dale Biochemistry Marijuana; molecular neurobiology of anandamide
     
Fu, Dax Brookhaven National Lab We seek to understand chemical principles governing selective binding and energized movement of zinc ions in membrane transporters.
     
Garcia-Diaz, Miguel Pharmacology Deficiencies in mitochondrial gene expression cause multiple human pathologies. Our lab combines structural, genetic and biochemical studies to understand the mechanism and function of proteins that are key for mitochondrial protein production, and investigate how the alteration of different gene expression processes can result in mitochondrial disfuction and disease.
     
Gergen, Peter Biochemistry Regulation of gene expression during Drosophila development
     
Green, David Applied Math & Statistics How can macromolecular interactions be engineered in a rational manner to have the desired effects in a complex environment, such as a living organism?
     
Grollman, Arthur Pharmacology Molecular Carcinogenesis: Mechanisms of DNA Repair and Mutagenesis in Mammalian Cells
     
Glynn, Steven Biochemistry Structure and mechanism of protein-unfolding machines in mitochondria
     
Haltiwanger, Robert Biochemistry Role of protein glycosylation in signal transduction and quality control
     
Holdener, Bernadette Biochemistry Role of mesd in embryonic development and trafficking the low-density lipoprotein receptor family
     
Karzai, Wali Biochemistry SmpB-tmRNA quality control system
     
Li, Huilin Biochemistry Structure and function of large protein machines
     
Liu, Chang-Jun Brookhaven National Lab Flavinoid/isoflavinoid & Plant cell wall pathways, Protein engineering
     
London, Erwin Biochemistry determining membrane protein structure and the origin of specific lipid-protein and protein-protein interactions
     
Luk, Ed Biochemistry & Cell Biology Chromosome biology and genome regulation
     
Martin, Benjamin Biochemistry & Cell Biology

Our laboratory uses zebrafish to understand the molecular basis of stem cell development and cancer pathogenesis.

     
McLaughlin, Stuart Physiology & Biophysics how physical factors (e.g. electrostatics, reduction of dimensionality) choreograph the diffusional dance of information through the calcium/phospholipid second messenger system
     
Miller, W. Todd Physiology & Biophysics Signal Transduction by Tyrosine Kinases
     
Neiman, Aaron Biochemistry The cell biology of sporulation in yeast
     
Raleigh, Daniel Chemistry protein folding, protein structure and the mechanism of amyloid formation
     
Reinitz, John Applied Math & Statistics  
     
Rizzo, Robert Applied Math & Statistics Structure-based drug design using computational methods; docking, molecular dynamics, virtual screening
     
Sampson, Nicole Chemistry protein structure and protein function and synthesizing chemical tools to probe and control biological function
     
Scarlata, Suzanne Physiology & Biophysics the ability of certain hormones and neurotransmitters to activate a family of proteins called "G Proteins"
     
Schwender, Jörg Brookhaven National Lab Metabolic flux analysis, Central carbon metabolism pathways
     
Schärer, Orlando Pharmacology/Chem Chemical Biology of Mammalian DNA Repair
     
Jessica C. Seeliger Pharmacology infectious disease, tuberculosis, lipid biosynthesis, membrane biology, enzymology
     
Seeliger, Markus Pharmacology Mechanism of Protein kinases and Ubiquitin Ligases in Cancer and Aging
     
Shanklin, John Brookhaven National Lab Lipid modifying enzymes, Protein engineering, Plant oils
     
Simmerling, Carlos Chemistry Computational structural biology: to accurately simulate known properties of molecules, assist in the refinement and interpretation of experimental data and predict the results of future experiments
     
Simon, Sanford Biochemistry mechanisms of action of serine proteases and metalloproteases from activated neutrophils
     
Smith, Steven Biochemistry Structure and function of membrane proteins
     
Sternglanz, Rolf Biochemistry Chromatin function in gene regulation
     
Swaminathan, Subramanyam Brookhaven National Lab Toxins, Rational drug design, Databases, Structural genomics
     
Thomsen, Gerald Biochemistry Mechanisms of cell fate determination and embryonic development
     
Tonge, Peter Chemistry how proteins control and modulate the properties of small molecule ligands
     
Wang, Jin Chemistry biomolecular folding and recognition, especially protein folding and protein-protein/protein-DNA interactions
     
Miller, Lisa Brookhaven National Lab  
     

 

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